Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

BibTeX

@article{allodium:10.1038/s41467-024-47606-9,
  title = {Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling},
  author = {Sebastijan Hobor and Maise Al Bakir and Crispin T. Hiley and Marcin Skrzypski and Alexander M. Frankell and Bjorn Bakker and Thomas B. K. Watkins and Aleksandra Markovets and Jonathan R. Dry and Andrew P. Brown and Jasper van der Aart and Hilda van den Bos and Diana Spierings and Dahmane Oukrif and Marco Novelli and Turja Chakrabarti and Adam H. Rabinowitz and Laila Ait Hassou and Saskia Litière and D. Lucas Kerr and Lisa Tan and Gavin Kelly and David A. Moore and Matthew J. Renshaw and Subramanian Venkatesan and William Hill and Ariana Huebner and Carlos Martínez-Ruiz and James R. M. Black and Wei Wu and Mihaela Angelova and Nicholas McGranahan and Julian Downward and Juliann Chmielecki and Carl Barrett and Kevin Litchfield and Su Kit Chew and Collin M. Blakely and Elza C. de Bruin and Floris Foijer and Karen H. Vousden and Trever G. Bivona and Unknown and Jason F. Lester and Amrita Bajaj and Apostolos Nakas and Azmina Sodha-Ramdeen and Mohamad Tufail and Molly Scotland and Rebecca Boyles and Sridhar Rathinam and Claire Wilson and Domenic Marrone and Sean Dulloo and Dean A. Fennell and Gurdeep Matharu and Jacqui A. Shaw and Ekaterini Boleti and Heather Cheyne and Mohammed Khalil and Shirley Richardson and Tracey Cruickshank and Gillian Price and Keith M. Kerr and Sarah Benafif and Jack French and Kayleigh Gilbert and Babu Naidu and Akshay J. Patel and Aya Osman and Carol Enstone and Gerald Langman and Helen Shackleford and Madava Djearaman and Salma Kadiri and Gary Middleton and Angela Leek and Jack Davies Hodgkinson and Nicola Totton and Angeles Montero and Elaine Smith and Eustace Fontaine and Felice Granato and Antonio Paiva-Correia and Juliette Novasio and Kendadai Rammohan and Leena Joseph and Paul Bishop and Rajesh Shah and Stuart Moss and Vijay Joshi and Philip A. J. Crosbie and Katherine D. Brown and Mathew Carter and Anshuman Chaturvedi and Pedro Oliveira and Colin R. Lindsay and Fiona H. Blackhall and Matthew G. Krebs and Yvonne Summers and Alexandra Clipson and Jonathan Tugwood and Alastair Kerr and Dominic G. Rothwell and Caroline Dive and Hugo J. W. L. Aerts and Roland F. Schwarz and Tom L. Kaufmann and Gareth A. Wilson and Rachel Rosenthal and Peter Van Loo and Nicolai J. Birkbak and Zoltan Szallasi and Judit Kisistok and Mateo Sokac and Roberto Salgado and Miklos Diossy and Jonas Demeulemeester and Abigail Bunkum and Angela Dwornik and Alastair Magness and Andrew J. Rowan and Angeliki Karamani and Antonia Toncheva and Benny Chain and Carla Castignani and Chris Bailey and Christopher Abbosh and Clare Puttick and Clare E. Weeden and Claudia Lee and Corentin Richard and Cristina Naceur-Lombardelli and David R. Pearce and Despoina Karagianni and Dhruva Biswas and Dina Levi and Elizabeth Larose Cadieux and Emilia L. Lim and Emma Colliver and Emma Nye and Felip Gálvez-Cancino and Francisco Gimeno-Valiente and George Kassiotis and Georgia Stavrou and Gerasimos-Theodoros Mastrokalos and Helen L. Lowe and Ignacio Garcia Matos and Imran Noorani and Jacki Goldman and James L. Reading and Jayant K. Rane and Jerome Nicod and John A. Hartley and Karl S. Peggs and Katey S. S. Enfield and Kayalvizhi Selvaraju and Kerstin Thol and Kevin W. Ng and Kezhong Chen and Krijn Dijkstra and Kristiana Grigoriadis and Krupa Thakkar and Leah Ensell and Mansi Shah and Maria Litovchenko and Mariam Jamal-Hanjani and Mariana Werner Sunderland and Matthew R. Huska and Mark S. Hill and Michelle Dietzen and Michelle M. Leung and Mickael Escudero and Miljana Tanić and Monica Sivakumar and Olga Chervova and Olivia Lucas and Oriol Pich and Othman Al-Sawaf and Paulina Prymas and Philip Hobson and Piotr Pawlik and Richard Kevin Stone and Robert Bentham and Roberto Vendramin and Sadegh Saghafinia and Samuel Gamble and Selvaraju Veeriah and Seng Kuong Anakin Ung and Sergio A. Quezada and Sharon Vanloo and Sonya Hessey and Sophia Ward and Sian Harries and Stefan Boeing and Stephan Beck and Supreet Kaur Bola and Takahiro Karasaki and Tamara Denner and Teresa Marafioti and Thomas Patrick Jones and Victoria Spanswick and Vittorio Barbè and Wei-Ting Lu and Wing Kin Liu and Yin Wu and Yutaka Naito and Zoe Ramsden and Catarina Veiga and Gary Royle and Charles-Antoine Collins-Fekete and Francesco Fraioli and Paul Ashford and Martin D. Forster and Siow Ming Lee and Elaine Borg and Mary Falzon and Dionysis Papadatos-Pastos and James Wilson and Tanya Ahmad and Alexander James Procter and Asia Ahmed and Magali N. Taylor and Arjun Nair and David Lawrence and Davide Patrini and Neal Navani and Ricky M. Thakrar and Sam M. Janes and Emilie Martinoni Hoogenboom and Fleur Monk and James W. Holding and Junaid Choudhary and Kunal Bhakhri and Marco Scarci and Pat Gorman and Reena Khiroya and Robert C. M. Stephens and Yien Ning Sophia Wong and Zoltan Kaplar and Steve Bandula and Allan Hackshaw and Anne-Marie Hacker and Abigail Sharp and Sean Smith and Harjot Kaur Dhanda and Camilla Pilotti and Rachel Leslie and Anca Grapa and Hanyun Zhang and Khalid AbdulJabbar and Xiaoxi Pan and Yinyin Yuan and David Chuter and Mairead MacKenzie and Serena Chee and Aiman Alzetani and Judith Cave and Jennifer Richards and Eric Lim and Paulo De Sousa and Simon Jordan and Alexandra Rice and Hilgardt Raubenheimer and Harshil Bhayani and Lyn Ambrose and Anand Devaraj and Hema Chavan and Sofina Begum and Silviu I. Buderi and Daniel Kaniu and Mpho Malima and Sarah Booth and Andrew G. Nicholson and Nadia Fernandes and Pratibha Shah and Chiara Proli and Madeleine Hewish and Sarah Danson and Michael J. Shackcloth and Lily Robinson and Peter Russell and Kevin G. Blyth and Andrew Kidd and Craig Dick and John Le Quesne and Alan Kirk and Mo Asif and Rocco Bilancia and Nikos Kostoulas and Mathew Thomas and Robert E. Hynds and Nnennaya Kanu and Simone Zaccaria and Eva Grönroos and Charles Swanton},
  year = {2024},
  journal = {Nature Communications},
  doi = {10.1038/s41467-024-47606-9},
  url = {https://doi.org/10.1038/s41467-024-47606-9}
}

RIS

TY  - JOUR
TI  - Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling
AU  - Sebastijan Hobor
AU  - Maise Al Bakir
AU  - Crispin T. Hiley
AU  - Marcin Skrzypski
AU  - Alexander M. Frankell
AU  - Bjorn Bakker
AU  - Thomas B. K. Watkins
AU  - Aleksandra Markovets
AU  - Jonathan R. Dry
AU  - Andrew P. Brown
AU  - Jasper van der Aart
AU  - Hilda van den Bos
AU  - Diana Spierings
AU  - Dahmane Oukrif
AU  - Marco Novelli
AU  - Turja Chakrabarti
AU  - Adam H. Rabinowitz
AU  - Laila Ait Hassou
AU  - Saskia Litière
AU  - D. Lucas Kerr
AU  - Lisa Tan
AU  - Gavin Kelly
AU  - David A. Moore
AU  - Matthew J. Renshaw
AU  - Subramanian Venkatesan
AU  - William Hill
AU  - Ariana Huebner
AU  - Carlos Martínez-Ruiz
AU  - James R. M. Black
AU  - Wei Wu
AU  - Mihaela Angelova
AU  - Nicholas McGranahan
AU  - Julian Downward
AU  - Juliann Chmielecki
AU  - Carl Barrett
AU  - Kevin Litchfield
AU  - Su Kit Chew
AU  - Collin M. Blakely
AU  - Elza C. de Bruin
AU  - Floris Foijer
AU  - Karen H. Vousden
AU  - Trever G. Bivona
AU  - Unknown
AU  - Jason F. Lester
AU  - Amrita Bajaj
AU  - Apostolos Nakas
AU  - Azmina Sodha-Ramdeen
AU  - Mohamad Tufail
AU  - Molly Scotland
AU  - Rebecca Boyles
AU  - Sridhar Rathinam
AU  - Claire Wilson
AU  - Domenic Marrone
AU  - Sean Dulloo
AU  - Dean A. Fennell
AU  - Gurdeep Matharu
AU  - Jacqui A. Shaw
AU  - Ekaterini Boleti
AU  - Heather Cheyne
AU  - Mohammed Khalil
AU  - Shirley Richardson
AU  - Tracey Cruickshank
AU  - Gillian Price
AU  - Keith M. Kerr
AU  - Sarah Benafif
AU  - Jack French
AU  - Kayleigh Gilbert
AU  - Babu Naidu
AU  - Akshay J. Patel
AU  - Aya Osman
AU  - Carol Enstone
AU  - Gerald Langman
AU  - Helen Shackleford
AU  - Madava Djearaman
AU  - Salma Kadiri
AU  - Gary Middleton
AU  - Angela Leek
AU  - Jack Davies Hodgkinson
AU  - Nicola Totton
AU  - Angeles Montero
AU  - Elaine Smith
AU  - Eustace Fontaine
AU  - Felice Granato
AU  - Antonio Paiva-Correia
AU  - Juliette Novasio
AU  - Kendadai Rammohan
AU  - Leena Joseph
AU  - Paul Bishop
AU  - Rajesh Shah
AU  - Stuart Moss
AU  - Vijay Joshi
AU  - Philip A. J. Crosbie
AU  - Katherine D. Brown
AU  - Mathew Carter
AU  - Anshuman Chaturvedi
AU  - Pedro Oliveira
AU  - Colin R. Lindsay
AU  - Fiona H. Blackhall
AU  - Matthew G. Krebs
AU  - Yvonne Summers
AU  - Alexandra Clipson
AU  - Jonathan Tugwood
AU  - Alastair Kerr
AU  - Dominic G. Rothwell
AU  - Caroline Dive
AU  - Hugo J. W. L. Aerts
AU  - Roland F. Schwarz
AU  - Tom L. Kaufmann
AU  - Gareth A. Wilson
AU  - Rachel Rosenthal
AU  - Peter Van Loo
AU  - Nicolai J. Birkbak
AU  - Zoltan Szallasi
AU  - Judit Kisistok
AU  - Mateo Sokac
AU  - Roberto Salgado
AU  - Miklos Diossy
AU  - Jonas Demeulemeester
AU  - Abigail Bunkum
AU  - Angela Dwornik
AU  - Alastair Magness
AU  - Andrew J. Rowan
AU  - Angeliki Karamani
AU  - Antonia Toncheva
AU  - Benny Chain
AU  - Carla Castignani
AU  - Chris Bailey
AU  - Christopher Abbosh
AU  - Clare Puttick
AU  - Clare E. Weeden
AU  - Claudia Lee
AU  - Corentin Richard
AU  - Cristina Naceur-Lombardelli
AU  - David R. Pearce
AU  - Despoina Karagianni
AU  - Dhruva Biswas
AU  - Dina Levi
AU  - Elizabeth Larose Cadieux
AU  - Emilia L. Lim
AU  - Emma Colliver
AU  - Emma Nye
AU  - Felip Gálvez-Cancino
AU  - Francisco Gimeno-Valiente
AU  - George Kassiotis
AU  - Georgia Stavrou
AU  - Gerasimos-Theodoros Mastrokalos
AU  - Helen L. Lowe
AU  - Ignacio Garcia Matos
AU  - Imran Noorani
AU  - Jacki Goldman
AU  - James L. Reading
AU  - Jayant K. Rane
AU  - Jerome Nicod
AU  - John A. Hartley
AU  - Karl S. Peggs
AU  - Katey S. S. Enfield
AU  - Kayalvizhi Selvaraju
AU  - Kerstin Thol
AU  - Kevin W. Ng
AU  - Kezhong Chen
AU  - Krijn Dijkstra
AU  - Kristiana Grigoriadis
AU  - Krupa Thakkar
AU  - Leah Ensell
AU  - Mansi Shah
AU  - Maria Litovchenko
AU  - Mariam Jamal-Hanjani
AU  - Mariana Werner Sunderland
AU  - Matthew R. Huska
AU  - Mark S. Hill
AU  - Michelle Dietzen
AU  - Michelle M. Leung
AU  - Mickael Escudero
AU  - Miljana Tanić
AU  - Monica Sivakumar
AU  - Olga Chervova
AU  - Olivia Lucas
AU  - Oriol Pich
AU  - Othman Al-Sawaf
AU  - Paulina Prymas
AU  - Philip Hobson
AU  - Piotr Pawlik
AU  - Richard Kevin Stone
AU  - Robert Bentham
AU  - Roberto Vendramin
AU  - Sadegh Saghafinia
AU  - Samuel Gamble
AU  - Selvaraju Veeriah
AU  - Seng Kuong Anakin Ung
AU  - Sergio A. Quezada
AU  - Sharon Vanloo
AU  - Sonya Hessey
AU  - Sophia Ward
AU  - Sian Harries
AU  - Stefan Boeing
AU  - Stephan Beck
AU  - Supreet Kaur Bola
AU  - Takahiro Karasaki
AU  - Tamara Denner
AU  - Teresa Marafioti
AU  - Thomas Patrick Jones
AU  - Victoria Spanswick
AU  - Vittorio Barbè
AU  - Wei-Ting Lu
AU  - Wing Kin Liu
AU  - Yin Wu
AU  - Yutaka Naito
AU  - Zoe Ramsden
AU  - Catarina Veiga
AU  - Gary Royle
AU  - Charles-Antoine Collins-Fekete
AU  - Francesco Fraioli
AU  - Paul Ashford
AU  - Martin D. Forster
AU  - Siow Ming Lee
AU  - Elaine Borg
AU  - Mary Falzon
AU  - Dionysis Papadatos-Pastos
AU  - James Wilson
AU  - Tanya Ahmad
AU  - Alexander James Procter
AU  - Asia Ahmed
AU  - Magali N. Taylor
AU  - Arjun Nair
AU  - David Lawrence
AU  - Davide Patrini
AU  - Neal Navani
AU  - Ricky M. Thakrar
AU  - Sam M. Janes
AU  - Emilie Martinoni Hoogenboom
AU  - Fleur Monk
AU  - James W. Holding
AU  - Junaid Choudhary
AU  - Kunal Bhakhri
AU  - Marco Scarci
AU  - Pat Gorman
AU  - Reena Khiroya
AU  - Robert C. M. Stephens
AU  - Yien Ning Sophia Wong
AU  - Zoltan Kaplar
AU  - Steve Bandula
AU  - Allan Hackshaw
AU  - Anne-Marie Hacker
AU  - Abigail Sharp
AU  - Sean Smith
AU  - Harjot Kaur Dhanda
AU  - Camilla Pilotti
AU  - Rachel Leslie
AU  - Anca Grapa
AU  - Hanyun Zhang
AU  - Khalid AbdulJabbar
AU  - Xiaoxi Pan
AU  - Yinyin Yuan
AU  - David Chuter
AU  - Mairead MacKenzie
AU  - Serena Chee
AU  - Aiman Alzetani
AU  - Judith Cave
AU  - Jennifer Richards
AU  - Eric Lim
AU  - Paulo De Sousa
AU  - Simon Jordan
AU  - Alexandra Rice
AU  - Hilgardt Raubenheimer
AU  - Harshil Bhayani
AU  - Lyn Ambrose
AU  - Anand Devaraj
AU  - Hema Chavan
AU  - Sofina Begum
AU  - Silviu I. Buderi
AU  - Daniel Kaniu
AU  - Mpho Malima
AU  - Sarah Booth
AU  - Andrew G. Nicholson
AU  - Nadia Fernandes
AU  - Pratibha Shah
AU  - Chiara Proli
AU  - Madeleine Hewish
AU  - Sarah Danson
AU  - Michael J. Shackcloth
AU  - Lily Robinson
AU  - Peter Russell
AU  - Kevin G. Blyth
AU  - Andrew Kidd
AU  - Craig Dick
AU  - John Le Quesne
AU  - Alan Kirk
AU  - Mo Asif
AU  - Rocco Bilancia
AU  - Nikos Kostoulas
AU  - Mathew Thomas
AU  - Robert E. Hynds
AU  - Nnennaya Kanu
AU  - Simone Zaccaria
AU  - Eva Grönroos
AU  - Charles Swanton
PY  - 2024
JO  - Nature Communications
DO  - 10.1038/s41467-024-47606-9
UR  - https://doi.org/10.1038/s41467-024-47606-9
ER  - 

APA

Hobor, S., Bakir, M. A., Hiley, C. T., Skrzypski, M., Frankell, A. M., Bakker, B., Watkins, T. B. K., Markovets, A., Dry, J. R., Brown, A. P., Aart, J. V. D., Bos, H. V. D., Spierings, D., Oukrif, D., Novelli, M., Chakrabarti, T., Rabinowitz, A. H., Hassou, L. A., Litière, S., Kerr, D. L., Tan, L., Kelly, G., Moore, D. A., Renshaw, M. J., Venkatesan, S., Hill, W., Huebner, A., Martínez-Ruiz, C., Black, J. R. M., Wu, W., Angelova, M., McGranahan, N., Downward, J., Chmielecki, J., Barrett, C., Litchfield, K., Chew, S. K., Blakely, C. M., Bruin, E. C. D., Foijer, F., Vousden, K. H., Bivona, T. G., Unknown, Lester, J. F., Bajaj, A., Nakas, A., Sodha-Ramdeen, A., Tufail, M., Scotland, M., Boyles, R., Rathinam, S., Wilson, C., Marrone, D., Dulloo, S., Fennell, D. A., Matharu, G., Shaw, J. A., Boleti, E., Cheyne, H., Khalil, M., Richardson, S., Cruickshank, T., Price, G., Kerr, K. M., Benafif, S., French, J., Gilbert, K., Naidu, B., Patel, A. J., Osman, A., Enstone, C., Langman, G., Shackleford, H., Djearaman, M., Kadiri, S., Middleton, G., Leek, A., Hodgkinson, J. D., Totton, N., Montero, A., Smith, E., Fontaine, E., Granato, F., Paiva-Correia, A., Novasio, J., Rammohan, K., Joseph, L., Bishop, P., Shah, R., Moss, S., Joshi, V., Crosbie, P. A. J., Brown, K. D., Carter, M., Chaturvedi, A., Oliveira, P., Lindsay, C. R., Blackhall, F. H., Krebs, M. G., Summers, Y., Clipson, A., Tugwood, J., Kerr, A., Rothwell, D. G., Dive, C., Aerts, H. J. W. L., Schwarz, R. F., Kaufmann, T. L., Wilson, G. A., Rosenthal, R., Loo, P. V., Birkbak, N. J., Szallasi, Z., Kisistok, J., Sokac, M., Salgado, R., Diossy, M., Demeulemeester, J., Bunkum, A., Dwornik, A., Magness, A., Rowan, A. J., Karamani, A., Toncheva, A., Chain, B., Castignani, C., Bailey, C., Abbosh, C., Puttick, C., Weeden, C. E., Lee, C., Richard, C., Naceur-Lombardelli, C., Pearce, D. R., Karagianni, D., Biswas, D., Levi, D., Cadieux, E. L., Lim, E. L., Colliver, E., Nye, E., Gálvez-Cancino, F., Gimeno-Valiente, F., Kassiotis, G., Stavrou, G., Mastrokalos, G., Lowe, H. L., Matos, I. G., Noorani, I., Goldman, J., Reading, J. L., Rane, J. K., Nicod, J., Hartley, J. A., Peggs, K. S., Enfield, K. S. S., Selvaraju, K., Thol, K., Ng, K. W., Chen, K., Dijkstra, K., Grigoriadis, K., Thakkar, K., Ensell, L., Shah, M., Litovchenko, M., Jamal-Hanjani, M., Sunderland, M. W., Huska, M. R., Hill, M. S., Dietzen, M., Leung, M. M., Escudero, M., Tanić, M., Sivakumar, M., Chervova, O., Lucas, O., Pich, O., Al-Sawaf, O., Prymas, P., Hobson, P., Pawlik, P., Stone, R. K., Bentham, R., Vendramin, R., Saghafinia, S., Gamble, S., Veeriah, S., Ung, S. K. A., Quezada, S. A., Vanloo, S., Hessey, S., Ward, S., Harries, S., Boeing, S., Beck, S., Bola, S. K., Karasaki, T., Denner, T., Marafioti, T., Jones, T. P., Spanswick, V., Barbè, V., Lu, W., Liu, W. K., Wu, Y., Naito, Y., Ramsden, Z., Veiga, C., Royle, G., Collins-Fekete, C., Fraioli, F., Ashford, P., Forster, M. D., Lee, S. M., Borg, E., Falzon, M., Papadatos-Pastos, D., Wilson, J., Ahmad, T., Procter, A. J., Ahmed, A., Taylor, M. N., Nair, A., Lawrence, D., Patrini, D., Navani, N., Thakrar, R. M., Janes, S. M., Hoogenboom, E. M., Monk, F., Holding, J. W., Choudhary, J., Bhakhri, K., Scarci, M., Gorman, P., Khiroya, R., Stephens, R. C. M., Wong, Y. N. S., Kaplar, Z., Bandula, S., Hackshaw, A., Hacker, A., Sharp, A., Smith, S., Dhanda, H. K., Pilotti, C., Leslie, R., Grapa, A., Zhang, H., AbdulJabbar, K., Pan, X., Yuan, Y., Chuter, D., MacKenzie, M., Chee, S., Alzetani, A., Cave, J., Richards, J., Lim, E., Sousa, P. D., Jordan, S., Rice, A., Raubenheimer, H., Bhayani, H., Ambrose, L., Devaraj, A., Chavan, H., Begum, S., Buderi, S. I., Kaniu, D., Malima, M., Booth, S., Nicholson, A. G., Fernandes, N., Shah, P., Proli, C., Hewish, M., Danson, S., Shackcloth, M. J., Robinson, L., Russell, P., Blyth, K. G., Kidd, A., Dick, C., Quesne, J. L., Kirk, A., Asif, M., Bilancia, R., Kostoulas, N., Thomas, M., Hynds, R. E., Kanu, N., Zaccaria, S., Grönroos, E., & Swanton, C. (2024). Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature Communications. https://doi.org/10.1038/s41467-024-47606-9