Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.

Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NS, Meyer M, Gupta S, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Le Marchand L, McDonald MN, McHugh CP, Morrison AC, Naseri T, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Ida Chen YD, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Benjamin Shoemaker M, Smith NL, Taylor KD, Telen MJ, Weiss ST, Zhang Y, Heard-Costa N, Sun YV, Lin X, Cupples LA, Lange LA, Liu CT, Loos RJF, North KE, Justice AE

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DOI: 10.1038/s41467-025-58420-2
Published: 2025 Apr 11
Container: Nature communications
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1038/s41467-025-58420-2,
  title = {Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.},
  author = {Zhang X and Brody JA and Graff M and Highland HM and Chami N and Xu H and Wang Z and Ferrier KR and Chittoor G and Josyula NS and Meyer M and Gupta S and Li X and Li Z and Allison MA and Becker DM and Bielak LF and Bis JC and Boorgula MP and Bowden DW and Broome JG and Buth EJ and Carlson CS and Chang KM and Chavan S and Chiu YF and Chuang LM and Conomos MP and DeMeo DL and Du M and Duggirala R and Eng C and Fohner AE and Freedman BI and Garrett ME and Guo X and Haiman C and Heavner BD and Hidalgo B and Hixson JE and Ho YL and Hobbs BD and Hu D and Hui Q and Hwu CM and Jackson RD and Jain D and Kalyani RR and Kardia SLR and Kelly TN and Lange EM and LeNoir M and Li C and Le Marchand L and McDonald MN and McHugh CP and Morrison AC and Naseri T and NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium and O'Connell J and O'Donnell CJ and Palmer ND and Pankow JS and Perry JA and Peters U and Preuss MH and Rao DC and Regan EA and Reupena SM and Roden DM and Rodriguez-Santana J and Sitlani CM and Smith JA and Tiwari HK and Vasan RS and Wang Z and Weeks DE and Wessel J and Wiggins KL and Wilkens LR and Wilson PWF and Yanek LR and Yoneda ZT and Zhao W and Zöllner S and Arnett DK and Ashley-Koch AE and Barnes KC and Blangero J and Boerwinkle E and Burchard EG and Carson AP and Chasman DI and Ida Chen YD and Curran JE and Fornage M and Gordeuk VR and He J and Heckbert SR and Hou L and Irvin MR and Kooperberg C and Minster RL and Mitchell BD and Nouraie M and Psaty BM and Raffield LM and Reiner AP and Rich SS and Rotter JI and Benjamin Shoemaker M and Smith NL and Taylor KD and Telen MJ and Weiss ST and Zhang Y and Heard-Costa N and Sun YV and Lin X and Cupples LA and Lange LA and Liu CT and Loos RJF and North KE and Justice AE},
  year = {2025},
  journal = {Nature communications},
  doi = {10.1038/s41467-025-58420-2},
  url = {https://doi.org/10.1038/s41467-025-58420-2}
}

RIS

TY  - JOUR
TI  - Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
AU  - Zhang X
AU  - Brody JA
AU  - Graff M
AU  - Highland HM
AU  - Chami N
AU  - Xu H
AU  - Wang Z
AU  - Ferrier KR
AU  - Chittoor G
AU  - Josyula NS
AU  - Meyer M
AU  - Gupta S
AU  - Li X
AU  - Li Z
AU  - Allison MA
AU  - Becker DM
AU  - Bielak LF
AU  - Bis JC
AU  - Boorgula MP
AU  - Bowden DW
AU  - Broome JG
AU  - Buth EJ
AU  - Carlson CS
AU  - Chang KM
AU  - Chavan S
AU  - Chiu YF
AU  - Chuang LM
AU  - Conomos MP
AU  - DeMeo DL
AU  - Du M
AU  - Duggirala R
AU  - Eng C
AU  - Fohner AE
AU  - Freedman BI
AU  - Garrett ME
AU  - Guo X
AU  - Haiman C
AU  - Heavner BD
AU  - Hidalgo B
AU  - Hixson JE
AU  - Ho YL
AU  - Hobbs BD
AU  - Hu D
AU  - Hui Q
AU  - Hwu CM
AU  - Jackson RD
AU  - Jain D
AU  - Kalyani RR
AU  - Kardia SLR
AU  - Kelly TN
AU  - Lange EM
AU  - LeNoir M
AU  - Li C
AU  - Le Marchand L
AU  - McDonald MN
AU  - McHugh CP
AU  - Morrison AC
AU  - Naseri T
AU  - NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
AU  - O'Connell J
AU  - O'Donnell CJ
AU  - Palmer ND
AU  - Pankow JS
AU  - Perry JA
AU  - Peters U
AU  - Preuss MH
AU  - Rao DC
AU  - Regan EA
AU  - Reupena SM
AU  - Roden DM
AU  - Rodriguez-Santana J
AU  - Sitlani CM
AU  - Smith JA
AU  - Tiwari HK
AU  - Vasan RS
AU  - Wang Z
AU  - Weeks DE
AU  - Wessel J
AU  - Wiggins KL
AU  - Wilkens LR
AU  - Wilson PWF
AU  - Yanek LR
AU  - Yoneda ZT
AU  - Zhao W
AU  - Zöllner S
AU  - Arnett DK
AU  - Ashley-Koch AE
AU  - Barnes KC
AU  - Blangero J
AU  - Boerwinkle E
AU  - Burchard EG
AU  - Carson AP
AU  - Chasman DI
AU  - Ida Chen YD
AU  - Curran JE
AU  - Fornage M
AU  - Gordeuk VR
AU  - He J
AU  - Heckbert SR
AU  - Hou L
AU  - Irvin MR
AU  - Kooperberg C
AU  - Minster RL
AU  - Mitchell BD
AU  - Nouraie M
AU  - Psaty BM
AU  - Raffield LM
AU  - Reiner AP
AU  - Rich SS
AU  - Rotter JI
AU  - Benjamin Shoemaker M
AU  - Smith NL
AU  - Taylor KD
AU  - Telen MJ
AU  - Weiss ST
AU  - Zhang Y
AU  - Heard-Costa N
AU  - Sun YV
AU  - Lin X
AU  - Cupples LA
AU  - Lange LA
AU  - Liu CT
AU  - Loos RJF
AU  - North KE
AU  - Justice AE
PY  - 2025
JO  - Nature communications
DO  - 10.1038/s41467-025-58420-2
UR  - https://doi.org/10.1038/s41467-025-58420-2
ER  -

APA

X, Z., JA, B., M, G., HM, H., N, C., H, X., Z, W., KR, F., G, C., NS, J., M, M., S, G., X, L., Z, L., MA, A., DM, B., LF, B., JC, B., MP, B., DW, B., JG, B., EJ, B., CS, C., KM, C., S, C., YF, C., LM, C., MP, C., DL, D., M, D., R, D., C, E., AE, F., BI, F., ME, G., X, G., C, H., BD, H., B, H., JE, H., YL, H., BD, H., D, H., Q, H., CM, H., RD, J., D, J., RR, K., SLR, K., TN, K., EM, L., M, L., C, L., L, L. M., MN, M., CP, M., AC, M., T, N., Consortium, N. T. F. P. M. (., J, O., CJ, O., ND, P., JS, P., JA, P., U, P., MH, P., DC, R., EA, R., SM, R., DM, R., J, R., CM, S., JA, S., HK, T., RS, V., Z, W., DE, W., J, W., KL, W., LR, W., PWF, W., LR, Y., ZT, Y., W, Z., S, Z., DK, A., AE, A., KC, B., J, B., E, B., EG, B., AP, C., DI, C., YD, I. C., JE, C., M, F., VR, G., J, H., SR, H., L, H., MR, I., C, K., RL, M., BD, M., M, N., BM, P., LM, R., AP, R., SS, R., JI, R., M, B. S., NL, S., KD, T., MJ, T., ST, W., Y, Z., N, H., YV, S., X, L., LA, C., LA, L., CT, L., RJF, L., KE, N., & AE, J. (2025). Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.. Nature communications. https://doi.org/10.1038/s41467-025-58420-2

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pubmed · retrieved 2026-11-11T01:48:08.989Z