A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands

Shihong Zhang, Tzu-Hao Tang, Sinéad Kinsella, Francesco Mazziotta, Michael T. Schweizer, Megan S. McAfee, Ariunaa Munkhbat, Yapeng Su, Valentin Voillet, Lauren E. Martin, Colton W. Smith, Yuta Asano, Menna Hailemariam, Jakob Bakhtiari, Bo Lee, Cecilia Yeung, Hung Chen, Alessandro M. Rizzi, Daniel G. Chen, Kelsey Furiya, Nick Horst, Tianzi Zhang, Phung Le, Kelly McKenna, Shannon K. Oda, Anthony Rongvaux, Phillip D. Greenberg, Thomas M. Schmitt, Aude G. Chapuis

Open source

DOI: 10.1038/s41467-025-67446-5
Published: 2026-01-03
Container: Nature Communications
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41467-025-67446-5,
  title = {A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands},
  author = {Shihong Zhang and Tzu-Hao Tang and Sinéad Kinsella and Francesco Mazziotta and Michael T. Schweizer and Megan S. McAfee and Ariunaa Munkhbat and Yapeng Su and Valentin Voillet and Lauren E. Martin and Colton W. Smith and Yuta Asano and Menna Hailemariam and Jakob Bakhtiari and Bo Lee and Cecilia Yeung and Hung Chen and Alessandro M. Rizzi and Daniel G. Chen and Kelsey Furiya and Nick Horst and Tianzi Zhang and Phung Le and Kelly McKenna and Shannon K. Oda and Anthony Rongvaux and Phillip D. Greenberg and Thomas M. Schmitt and Aude G. Chapuis},
  year = {2026},
  journal = {Nature Communications},
  doi = {10.1038/s41467-025-67446-5},
  url = {https://doi.org/10.1038/s41467-025-67446-5}
}

RIS

TY  - JOUR
TI  - A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands
AU  - Shihong Zhang
AU  - Tzu-Hao Tang
AU  - Sinéad Kinsella
AU  - Francesco Mazziotta
AU  - Michael T. Schweizer
AU  - Megan S. McAfee
AU  - Ariunaa Munkhbat
AU  - Yapeng Su
AU  - Valentin Voillet
AU  - Lauren E. Martin
AU  - Colton W. Smith
AU  - Yuta Asano
AU  - Menna Hailemariam
AU  - Jakob Bakhtiari
AU  - Bo Lee
AU  - Cecilia Yeung
AU  - Hung Chen
AU  - Alessandro M. Rizzi
AU  - Daniel G. Chen
AU  - Kelsey Furiya
AU  - Nick Horst
AU  - Tianzi Zhang
AU  - Phung Le
AU  - Kelly McKenna
AU  - Shannon K. Oda
AU  - Anthony Rongvaux
AU  - Phillip D. Greenberg
AU  - Thomas M. Schmitt
AU  - Aude G. Chapuis
PY  - 2026
JO  - Nature Communications
DO  - 10.1038/s41467-025-67446-5
UR  - https://doi.org/10.1038/s41467-025-67446-5
ER  -

APA

Zhang, S., Tang, T., Kinsella, S., Mazziotta, F., Schweizer, M. T., McAfee, M. S., Munkhbat, A., Su, Y., Voillet, V., Martin, L. E., Smith, C. W., Asano, Y., Hailemariam, M., Bakhtiari, J., Lee, B., Yeung, C., Chen, H., Rizzi, A. M., Chen, D. G., Furiya, K., Horst, N., Zhang, T., Le, P., McKenna, K., Oda, S. K., Rongvaux, A., Greenberg, P. D., Schmitt, T. M., & Chapuis, A. G. (2026). A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands. Nature Communications. https://doi.org/10.1038/s41467-025-67446-5

Source records

crossref · retrieved 2026-09-27T16:47:51.919Z