An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models.

Ontoria JM, Torrente E, Missineo A, Alli C, Graziani R, Conti S, Bisbocci M, Quotadamo A, Ferrigno F, Corio A, Ievoli G, Bencheva L, Amaudrut J, Vasile S, Beghetto E, Paolini C, Alaimo N, Veneziano M, Nibbio M, Orsale MV, Proto G, Colaceci F, Orsatti L, Pucci V, Di Fabio R, Tomei L, Montalbetti C, Bresciani A, Toniatti C, Paonessa G

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DOI: 10.1038/s41467-026-68943-x
Published: 2026 Feb 10
Container: Nature communications
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1038/s41467-026-68943-x,
  title = {An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models.},
  author = {Ontoria JM and Torrente E and Missineo A and Alli C and Graziani R and Conti S and Bisbocci M and Quotadamo A and Ferrigno F and Corio A and Ievoli G and Bencheva L and Amaudrut J and Vasile S and Beghetto E and Paolini C and Alaimo N and Veneziano M and Nibbio M and Orsale MV and Proto G and Colaceci F and Orsatti L and Pucci V and Di Fabio R and Tomei L and Montalbetti C and Bresciani A and Toniatti C and Paonessa G},
  year = {2026},
  journal = {Nature communications},
  doi = {10.1038/s41467-026-68943-x},
  url = {https://doi.org/10.1038/s41467-026-68943-x}
}

RIS

TY  - JOUR
TI  - An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models.
AU  - Ontoria JM
AU  - Torrente E
AU  - Missineo A
AU  - Alli C
AU  - Graziani R
AU  - Conti S
AU  - Bisbocci M
AU  - Quotadamo A
AU  - Ferrigno F
AU  - Corio A
AU  - Ievoli G
AU  - Bencheva L
AU  - Amaudrut J
AU  - Vasile S
AU  - Beghetto E
AU  - Paolini C
AU  - Alaimo N
AU  - Veneziano M
AU  - Nibbio M
AU  - Orsale MV
AU  - Proto G
AU  - Colaceci F
AU  - Orsatti L
AU  - Pucci V
AU  - Di Fabio R
AU  - Tomei L
AU  - Montalbetti C
AU  - Bresciani A
AU  - Toniatti C
AU  - Paonessa G
PY  - 2026
JO  - Nature communications
DO  - 10.1038/s41467-026-68943-x
UR  - https://doi.org/10.1038/s41467-026-68943-x
ER  -

APA

JM, O., E, T., A, M., C, A., R, G., S, C., M, B., A, Q., F, F., A, C., G, I., L, B., J, A., S, V., E, B., C, P., N, A., M, V., M, N., MV, O., G, P., F, C., L, O., V, P., R, D. F., L, T., C, M., A, B., C, T., & G, P. (2026). An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models.. Nature communications. https://doi.org/10.1038/s41467-026-68943-x

Source records

pubmed · retrieved 2026-09-26T01:57:34.868Z