PD-1 antibody-bound progenitor-exhausted CD8+ T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer

Yohei Nose, Yoshiaki Yasumizu, Takuro Saito, Yamami Nakamura, Koichi Jinushi, Kaoru Fujikawa, Kota Momose, Kotaro Yamashita, Koji Tanaka, Kazuyoshi Yamamoto, Tomoki Makino, Tsuyoshi Takahashi, Azumi Ueyama, Yukinori Kurokawa, Eiichi Sato, Naganari Ohkura, Shimon Sakaguchi, Hisashi Wada, Hidetoshi Eguchi, Yuichiro Doki

Open source

DOI: 10.1038/s41467-026-70751-2
Published: 2026-04-08
Container: Nature Communications
Publisher: Springer Science and Business Media LLC
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41467-026-70751-2,
  title = {PD-1 antibody-bound progenitor-exhausted CD8+ T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer},
  author = {Yohei Nose and Yoshiaki Yasumizu and Takuro Saito and Yamami Nakamura and Koichi Jinushi and Kaoru Fujikawa and Kota Momose and Kotaro Yamashita and Koji Tanaka and Kazuyoshi Yamamoto and Tomoki Makino and Tsuyoshi Takahashi and Azumi Ueyama and Yukinori Kurokawa and Eiichi Sato and Naganari Ohkura and Shimon Sakaguchi and Hisashi Wada and Hidetoshi Eguchi and Yuichiro Doki},
  year = {2026},
  journal = {Nature Communications},
  doi = {10.1038/s41467-026-70751-2},
  url = {https://doi.org/10.1038/s41467-026-70751-2}
}

RIS

TY  - JOUR
TI  - PD-1 antibody-bound progenitor-exhausted CD8+ T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer
AU  - Yohei Nose
AU  - Yoshiaki Yasumizu
AU  - Takuro Saito
AU  - Yamami Nakamura
AU  - Koichi Jinushi
AU  - Kaoru Fujikawa
AU  - Kota Momose
AU  - Kotaro Yamashita
AU  - Koji Tanaka
AU  - Kazuyoshi Yamamoto
AU  - Tomoki Makino
AU  - Tsuyoshi Takahashi
AU  - Azumi Ueyama
AU  - Yukinori Kurokawa
AU  - Eiichi Sato
AU  - Naganari Ohkura
AU  - Shimon Sakaguchi
AU  - Hisashi Wada
AU  - Hidetoshi Eguchi
AU  - Yuichiro Doki
PY  - 2026
JO  - Nature Communications
DO  - 10.1038/s41467-026-70751-2
UR  - https://doi.org/10.1038/s41467-026-70751-2
ER  -

APA

Nose, Y., Yasumizu, Y., Saito, T., Nakamura, Y., Jinushi, K., Fujikawa, K., Momose, K., Yamashita, K., Tanaka, K., Yamamoto, K., Makino, T., Takahashi, T., Ueyama, A., Kurokawa, Y., Sato, E., Ohkura, N., Sakaguchi, S., Wada, H., Eguchi, H., & Doki, Y. (2026). PD-1 antibody-bound progenitor-exhausted CD8+ T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer. Nature Communications. https://doi.org/10.1038/s41467-026-70751-2

Source records

crossref · retrieved 2026-09-25T21:00:07.662Z