Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation.

Omura SN, Nakagawa R, Kajimoto S, Okazaki S, Ishiguro S, Mori H, Onishi K, Kashiwakura Y, Hiramoto T, Horinaka K, Tanaka M, Hirano H, Jividen K, Yamashita K, Tsai SQ, Yachie N, Ohmori T, Nishimasu H, Nureki O

Open source

DOI
10.1038/s41467-026-71626-2
Published
2026 Apr 16
Container
Nature communications
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41467-026-71626-2,
  title = {Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation.},
  author = {Omura SN and Nakagawa R and Kajimoto S and Okazaki S and Ishiguro S and Mori H and Onishi K and Kashiwakura Y and Hiramoto T and Horinaka K and Tanaka M and Hirano H and Jividen K and Yamashita K and Tsai SQ and Yachie N and Ohmori T and Nishimasu H and Nureki O},
  year = {2026},
  journal = {Nature communications},
  doi = {10.1038/s41467-026-71626-2},
  url = {https://doi.org/10.1038/s41467-026-71626-2}
}

RIS

TY  - JOUR
TI  - Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation.
AU  - Omura SN
AU  - Nakagawa R
AU  - Kajimoto S
AU  - Okazaki S
AU  - Ishiguro S
AU  - Mori H
AU  - Onishi K
AU  - Kashiwakura Y
AU  - Hiramoto T
AU  - Horinaka K
AU  - Tanaka M
AU  - Hirano H
AU  - Jividen K
AU  - Yamashita K
AU  - Tsai SQ
AU  - Yachie N
AU  - Ohmori T
AU  - Nishimasu H
AU  - Nureki O
PY  - 2026
JO  - Nature communications
DO  - 10.1038/s41467-026-71626-2
UR  - https://doi.org/10.1038/s41467-026-71626-2
ER  - 

APA

SN, O., R, N., S, K., S, O., S, I., H, M., K, O., Y, K., T, H., K, H., M, T., H, H., K, J., K, Y., SQ, T., N, Y., T, O., H, N., & O, N. (2026). Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation.. Nature communications. https://doi.org/10.1038/s41467-026-71626-2

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