CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials

Wallace Bourgeois, Hannah E. Rice, Daniela V. Wenge, Florian Perner, Hong Yue, Brandon D. Regalado, George Wan, Jan C. Schroeder, Alba Sommerschield, Charlie Hatton, Shivendra Singh, Sweta Singh, Shipra Bijpuria, Brian M. McKeever, William H. Miller, Jordan F. Safer, Sumaiya Iqbal, Jennifer A. Perry, Eric S. Fischer, John G. Doench, Gerard M. McGeehan, Jevon A. Cutler, Scott A. Armstrong

Open source

DOI: 10.1038/s41467-026-72685-1
Published: 2026-05-09
Container: Nature Communications
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41467-026-72685-1,
  title = {CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials},
  author = {Wallace Bourgeois and Hannah E. Rice and Daniela V. Wenge and Florian Perner and Hong Yue and Brandon D. Regalado and George Wan and Jan C. Schroeder and Alba Sommerschield and Charlie Hatton and Shivendra Singh and Sweta Singh and Shipra Bijpuria and Brian M. McKeever and William H. Miller and Jordan F. Safer and Sumaiya Iqbal and Jennifer A. Perry and Eric S. Fischer and John G. Doench and Gerard M. McGeehan and Jevon A. Cutler and Scott A. Armstrong},
  year = {2026},
  journal = {Nature Communications},
  doi = {10.1038/s41467-026-72685-1},
  url = {https://doi.org/10.1038/s41467-026-72685-1}
}

RIS

TY  - JOUR
TI  - CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials
AU  - Wallace Bourgeois
AU  - Hannah E. Rice
AU  - Daniela V. Wenge
AU  - Florian Perner
AU  - Hong Yue
AU  - Brandon D. Regalado
AU  - George Wan
AU  - Jan C. Schroeder
AU  - Alba Sommerschield
AU  - Charlie Hatton
AU  - Shivendra Singh
AU  - Sweta Singh
AU  - Shipra Bijpuria
AU  - Brian M. McKeever
AU  - William H. Miller
AU  - Jordan F. Safer
AU  - Sumaiya Iqbal
AU  - Jennifer A. Perry
AU  - Eric S. Fischer
AU  - John G. Doench
AU  - Gerard M. McGeehan
AU  - Jevon A. Cutler
AU  - Scott A. Armstrong
PY  - 2026
JO  - Nature Communications
DO  - 10.1038/s41467-026-72685-1
UR  - https://doi.org/10.1038/s41467-026-72685-1
ER  -

APA

Bourgeois, W., Rice, H. E., Wenge, D. V., Perner, F., Yue, H., Regalado, B. D., Wan, G., Schroeder, J. C., Sommerschield, A., Hatton, C., Singh, S., Singh, S., Bijpuria, S., McKeever, B. M., Miller, W. H., Safer, J. F., Iqbal, S., Perry, J. A., Fischer, E. S., Doench, J. G., McGeehan, G. M., Cutler, J. A., & Armstrong, S. A. (2026). CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials. Nature Communications. https://doi.org/10.1038/s41467-026-72685-1

Source records

crossref · retrieved 2026-09-27T14:04:12.063Z