Local, but not circulating, complement C3 shapes immune checkpoint blockade efficacy by controlling myeloid cell infiltration.

Miyai Y, Shiraki Y, Ando R, Sugiyama D, Sato Y, Kato K, Asai N, Cao F, Nagao N, Tanabe K, Nakatochi M, Hase T, Chen-Yoshikawa TF, Kobayashi T, Iwama S, Esaki N, Mii S, Arima H, Kimura H, Takahashi M, Ando Y, Enomoto A

Open source

DOI: 10.1038/s41467-026-75542-3
Published: 2026 Jul 15
Container: Nature communications
Publisher: Not recorded
Open access: yes

Credibility signals

uncertain Score 53/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
supportingDirectory of Open Access Journals: A matching record was returned by DOAJ. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41467-026-75542-3,
  title = {Local, but not circulating, complement C3 shapes immune checkpoint blockade efficacy by controlling myeloid cell infiltration.},
  author = {Miyai Y and Shiraki Y and Ando R and Sugiyama D and Sato Y and Kato K and Asai N and Cao F and Nagao N and Tanabe K and Nakatochi M and Hase T and Chen-Yoshikawa TF and Kobayashi T and Iwama S and Esaki N and Mii S and Arima H and Kimura H and Takahashi M and Ando Y and Enomoto A},
  year = {2026},
  journal = {Nature communications},
  doi = {10.1038/s41467-026-75542-3},
  url = {https://doi.org/10.1038/s41467-026-75542-3}
}

RIS

TY  - JOUR
TI  - Local, but not circulating, complement C3 shapes immune checkpoint blockade efficacy by controlling myeloid cell infiltration.
AU  - Miyai Y
AU  - Shiraki Y
AU  - Ando R
AU  - Sugiyama D
AU  - Sato Y
AU  - Kato K
AU  - Asai N
AU  - Cao F
AU  - Nagao N
AU  - Tanabe K
AU  - Nakatochi M
AU  - Hase T
AU  - Chen-Yoshikawa TF
AU  - Kobayashi T
AU  - Iwama S
AU  - Esaki N
AU  - Mii S
AU  - Arima H
AU  - Kimura H
AU  - Takahashi M
AU  - Ando Y
AU  - Enomoto A
PY  - 2026
JO  - Nature communications
DO  - 10.1038/s41467-026-75542-3
UR  - https://doi.org/10.1038/s41467-026-75542-3
ER  -

APA

Y, M., Y, S., R, A., D, S., Y, S., K, K., N, A., F, C., N, N., K, T., M, N., T, H., TF, C., T, K., S, I., N, E., S, M., H, A., H, K., M, T., Y, A., & A, E. (2026). Local, but not circulating, complement C3 shapes immune checkpoint blockade efficacy by controlling myeloid cell infiltration.. Nature communications. https://doi.org/10.1038/s41467-026-75542-3

Source records

pubmed · retrieved 2026-09-26T04:04:40.184Z
europe-pmc · retrieved 2026-09-26T04:04:40.205Z
doaj · retrieved 2026-09-26T04:04:40.177Z