Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer

Ignaty Leshchiner, Arielle J. Medford, Justin Cha, Lesli A. Kiedrowski, Andrzej Niemierko, Jennifer C. Keenan, Charles S. Dai, Laura M. Spring, Beverly Moy, Seth A. Wander, Neelima Vidula, Steven J. Isakoff, Dejan Juric, Mendy Miller, Andrew A. Davis, Lorenzo Gerratana, Ami Shah, Ben H. Park, Adam Brufsky, Joyce O’Shaughnessy, Rebecca J. Nagy, Leif W. Ellisen, Massimo Cristofanilli, Aditya Bardia, Gad Getz

Open source

DOI: 10.1038/s41467-026-75976-9
Published: 2026-09-22
Container: Nature Communications
Publisher: Springer Science and Business Media LLC
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41467-026-75976-9,
  title = {Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer},
  author = {Ignaty Leshchiner and Arielle J. Medford and Justin Cha and Lesli A. Kiedrowski and Andrzej Niemierko and Jennifer C. Keenan and Charles S. Dai and Laura M. Spring and Beverly Moy and Seth A. Wander and Neelima Vidula and Steven J. Isakoff and Dejan Juric and Mendy Miller and Andrew A. Davis and Lorenzo Gerratana and Ami Shah and Ben H. Park and Adam Brufsky and Joyce O’Shaughnessy and Rebecca J. Nagy and Leif W. Ellisen and Massimo Cristofanilli and Aditya Bardia and Gad Getz},
  year = {2026},
  journal = {Nature Communications},
  doi = {10.1038/s41467-026-75976-9},
  url = {https://doi.org/10.1038/s41467-026-75976-9}
}

RIS

TY  - JOUR
TI  - Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer
AU  - Ignaty Leshchiner
AU  - Arielle J. Medford
AU  - Justin Cha
AU  - Lesli A. Kiedrowski
AU  - Andrzej Niemierko
AU  - Jennifer C. Keenan
AU  - Charles S. Dai
AU  - Laura M. Spring
AU  - Beverly Moy
AU  - Seth A. Wander
AU  - Neelima Vidula
AU  - Steven J. Isakoff
AU  - Dejan Juric
AU  - Mendy Miller
AU  - Andrew A. Davis
AU  - Lorenzo Gerratana
AU  - Ami Shah
AU  - Ben H. Park
AU  - Adam Brufsky
AU  - Joyce O’Shaughnessy
AU  - Rebecca J. Nagy
AU  - Leif W. Ellisen
AU  - Massimo Cristofanilli
AU  - Aditya Bardia
AU  - Gad Getz
PY  - 2026
JO  - Nature Communications
DO  - 10.1038/s41467-026-75976-9
UR  - https://doi.org/10.1038/s41467-026-75976-9
ER  -

APA

Leshchiner, I., Medford, A. J., Cha, J., Kiedrowski, L. A., Niemierko, A., Keenan, J. C., Dai, C. S., Spring, L. M., Moy, B., Wander, S. A., Vidula, N., Isakoff, S. J., Juric, D., Miller, M., Davis, A. A., Gerratana, L., Shah, A., Park, B. H., Brufsky, A., O’Shaughnessy, J., Nagy, R. J., Ellisen, L. W., Cristofanilli, M., Bardia, A., & Getz, G. (2026). Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer. Nature Communications. https://doi.org/10.1038/s41467-026-75976-9

Source records

crossref · retrieved 2026-11-09T18:20:29.326Z