A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen.

Ma Q, Huang J, Mak E, Martinez Pomier K, Zhou P, Akimoto M, Ivetic N, Nazy I, Melacini G

Open source

DOI
10.1038/s41467-026-76387-6
Published
2026 Sep 11
Container
Nature communications
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41467-026-76387-6,
  title = {A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen.},
  author = {Ma Q and Huang J and Mak E and Martinez Pomier K and Zhou P and Akimoto M and Ivetic N and Nazy I and Melacini G},
  year = {2026},
  journal = {Nature communications},
  doi = {10.1038/s41467-026-76387-6},
  url = {https://doi.org/10.1038/s41467-026-76387-6}
}

RIS

TY  - JOUR
TI  - A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen.
AU  - Ma Q
AU  - Huang J
AU  - Mak E
AU  - Martinez Pomier K
AU  - Zhou P
AU  - Akimoto M
AU  - Ivetic N
AU  - Nazy I
AU  - Melacini G
PY  - 2026
JO  - Nature communications
DO  - 10.1038/s41467-026-76387-6
UR  - https://doi.org/10.1038/s41467-026-76387-6
ER  - 

APA

Q, M., J, H., E, M., K, M. P., P, Z., M, A., N, I., I, N., & G, M. (2026). A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen.. Nature communications. https://doi.org/10.1038/s41467-026-76387-6

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