Data-driven construction of an imine reductase library capable of broad-scope reductive amination at equimolar substrate concentrations

Sarah A. Berger, Christopher Grimm, Marco Cespugli, Andreas Krassnigg, Tobias Schopper, Irene Marzuoli, Isabel Oroz-Guinea, Stephan Vrabl, Lukas Roemer, Melanie A. Weber, Fabian M. Kulier, Yuliya Orel, Bettina M. Nestl, Christian C. Gruber, Georg Steinkellner, Serena Bisagni, Francis Gosselin, Hans Iding, Kurt Puentener, Dennis Wetzl, Wolfgang Kroutil, Joerg H. Schrittwieser

Open source

DOI
10.1038/s41467-026-76869-7
Published
2026-08-22
Container
Nature Communications
Publisher
Springer Science and Business Media LLC
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1038/s41467-026-76869-7,
  title = {Data-driven construction of an imine reductase library capable of broad-scope reductive amination at equimolar substrate concentrations},
  author = {Sarah A. Berger and Christopher Grimm and Marco Cespugli and Andreas Krassnigg and Tobias Schopper and Irene Marzuoli and Isabel Oroz-Guinea and Stephan Vrabl and Lukas Roemer and Melanie A. Weber and Fabian M. Kulier and Yuliya Orel and Bettina M. Nestl and Christian C. Gruber and Georg Steinkellner and Serena Bisagni and Francis Gosselin and Hans Iding and Kurt Puentener and Dennis Wetzl and Wolfgang Kroutil and Joerg H. Schrittwieser},
  year = {2026},
  journal = {Nature Communications},
  doi = {10.1038/s41467-026-76869-7},
  url = {https://doi.org/10.1038/s41467-026-76869-7}
}

RIS

TY  - JOUR
TI  - Data-driven construction of an imine reductase library capable of broad-scope reductive amination at equimolar substrate concentrations
AU  - Sarah A. Berger
AU  - Christopher Grimm
AU  - Marco Cespugli
AU  - Andreas Krassnigg
AU  - Tobias Schopper
AU  - Irene Marzuoli
AU  - Isabel Oroz-Guinea
AU  - Stephan Vrabl
AU  - Lukas Roemer
AU  - Melanie A. Weber
AU  - Fabian M. Kulier
AU  - Yuliya Orel
AU  - Bettina M. Nestl
AU  - Christian C. Gruber
AU  - Georg Steinkellner
AU  - Serena Bisagni
AU  - Francis Gosselin
AU  - Hans Iding
AU  - Kurt Puentener
AU  - Dennis Wetzl
AU  - Wolfgang Kroutil
AU  - Joerg H. Schrittwieser
PY  - 2026
JO  - Nature Communications
DO  - 10.1038/s41467-026-76869-7
UR  - https://doi.org/10.1038/s41467-026-76869-7
ER  - 

APA

Berger, S. A., Grimm, C., Cespugli, M., Krassnigg, A., Schopper, T., Marzuoli, I., Oroz-Guinea, I., Vrabl, S., Roemer, L., Weber, M. A., Kulier, F. M., Orel, Y., Nestl, B. M., Gruber, C. C., Steinkellner, G., Bisagni, S., Gosselin, F., Iding, H., Puentener, K., Wetzl, D., Kroutil, W., & Schrittwieser, J. H. (2026). Data-driven construction of an imine reductase library capable of broad-scope reductive amination at equimolar substrate concentrations. Nature Communications. https://doi.org/10.1038/s41467-026-76869-7

Source records