Safety and immunogenicity of a BPL-inactivated, whole-virus, universal influenza vaccine: a randomized, double-blinded, double-dummy, placebo-controlled, phase 1 clinical trial

Luca T. Giurgea, Alison Han, Lindsay M. Czajkowski, Holly Ann Baus, Gregory Mak, Matthias Lingemann, Ian Bellayr, Adriana Cervantes-Medina, Monica Gouzoulis, Kimberly Adao, Jenna Sherry, Rani Athota, Jackqueline Ardo, Robert Daniels, Viviane Callier, Jaekeun Park, Sally Hunsberger, Mattia Bonsignori, John H. Powers, John C. Kash, Jeffery K. Taubenberger, Matthew J. Memoli

Open source

DOI: 10.1038/s41467-026-78583-w
Published: 2026-10-12
Container: Nature Communications
Publisher: Springer Science and Business Media LLC
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41467-026-78583-w,
  title = {Safety and immunogenicity of a BPL-inactivated, whole-virus, universal influenza vaccine: a randomized, double-blinded, double-dummy, placebo-controlled, phase 1 clinical trial},
  author = {Luca T. Giurgea and Alison Han and Lindsay M. Czajkowski and Holly Ann Baus and Gregory Mak and Matthias Lingemann and Ian Bellayr and Adriana Cervantes-Medina and Monica Gouzoulis and Kimberly Adao and Jenna Sherry and Rani Athota and Jackqueline Ardo and Robert Daniels and Viviane Callier and Jaekeun Park and Sally Hunsberger and Mattia Bonsignori and John H. Powers and John C. Kash and Jeffery K. Taubenberger and Matthew J. Memoli},
  year = {2026},
  journal = {Nature Communications},
  doi = {10.1038/s41467-026-78583-w},
  url = {https://doi.org/10.1038/s41467-026-78583-w}
}

RIS

TY  - JOUR
TI  - Safety and immunogenicity of a BPL-inactivated, whole-virus, universal influenza vaccine: a randomized, double-blinded, double-dummy, placebo-controlled, phase 1 clinical trial
AU  - Luca T. Giurgea
AU  - Alison Han
AU  - Lindsay M. Czajkowski
AU  - Holly Ann Baus
AU  - Gregory Mak
AU  - Matthias Lingemann
AU  - Ian Bellayr
AU  - Adriana Cervantes-Medina
AU  - Monica Gouzoulis
AU  - Kimberly Adao
AU  - Jenna Sherry
AU  - Rani Athota
AU  - Jackqueline Ardo
AU  - Robert Daniels
AU  - Viviane Callier
AU  - Jaekeun Park
AU  - Sally Hunsberger
AU  - Mattia Bonsignori
AU  - John H. Powers
AU  - John C. Kash
AU  - Jeffery K. Taubenberger
AU  - Matthew J. Memoli
PY  - 2026
JO  - Nature Communications
DO  - 10.1038/s41467-026-78583-w
UR  - https://doi.org/10.1038/s41467-026-78583-w
ER  -

APA

Giurgea, L. T., Han, A., Czajkowski, L. M., Baus, H. A., Mak, G., Lingemann, M., Bellayr, I., Cervantes-Medina, A., Gouzoulis, M., Adao, K., Sherry, J., Athota, R., Ardo, J., Daniels, R., Callier, V., Park, J., Hunsberger, S., Bonsignori, M., Powers, J. H., Kash, J. C., Taubenberger, J. K., & Memoli, M. J. (2026). Safety and immunogenicity of a BPL-inactivated, whole-virus, universal influenza vaccine: a randomized, double-blinded, double-dummy, placebo-controlled, phase 1 clinical trial. Nature Communications. https://doi.org/10.1038/s41467-026-78583-w

Source records

crossref · retrieved 2026-11-10T16:52:57.281Z