Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer.

Barnes DR, Tyrer JP, Dennis J, Leslie G, Bolla MK, Lush M, Aeilts AM, Aittomäki K, Andrieu N, Andrulis IL, Anton-Culver H, Arason A, Arun BK, Balmaña J, Bandera EV, Barkardottir RB, Berger LPV, Berrington de Gonzalez A, Berthet P, Białkowska K, Bjørge L, Blanco AM, Blok MJ, Bobolis KA, Bogdanova NV, Brenton JD, Butz H, Buys SS, Caligo MA, Campbell I, Castillo C, Claes KBM, Colonna SV, Cook LS, Daly MB, Dansonka-Mieszkowska A, de la Hoya M, deFazio A, DePersia A, Ding YC, Doherty JA, Domchek SM, Dörk T, Einbeigi Z, Engel C, Evans DG, Foretova L, Fortner RT, Fostira F, Foti MC, Friedman E, Frone MN, Ganz PA, Gentry-Maharaj A, Glendon G, Godwin AK, González-Neira A, Greene MH, Gronwald J, Guerrieri-Gonzaga A, Hamann U, Hansen TVO, Harris HR, Hauke J, Heitz F, Hogervorst FBL, Hooning MJ, Hopper JL, Huff CD, Huntsman DG, Imyanitov EN, Izatt L, Jakubowska A, James PA, Janavicius R, John EM, Kar S, Karlan BY, Kennedy CJ, Kiemeney LALM, Konstantopoulou I, Kupryjanczyk J, Laitman Y, Lavie O, Lawrenson K, Lester J, Lesueur F, Lopez-Pleguezuelos C, Mai PL, Manoukian S, May T, McNeish IA, Menon U, Milne RL, Modugno F, Mongiovi JM, Montagna M, Moysich KB, Neuhausen SL, Nielsen FC, Noguès C, Oláh E, Olopade OI, Osorio A, Papi L, Pathak H, Pearce CL, Pedersen IS, Peixoto A, Pejovic T, Peng PC, Peshkin BN, Peterlongo P, Powell CB, Prokofyeva D, Pujana MA, Radice P, Rashid MU, Rennert G, Richenberg G, Sandler DP, Sasamoto N, Setiawan VW, Sharma P, Sieh W, Singer CF, Snape K, Sokolenko AP, Soucy P, Southey MC, Stoppa-Lyonnet D, Sutphen R, Sutter C, Tan YY, Teixeira MR, Terry KL, Thomsen LCV, Tischkowitz M, Toland AE, Van Gorp T, Vega A, Velez Edwards DR, Webb PM, Weitzel JN, Wentzensen N, Whittemore AS, Winham SJ, Wu AH, Yadav S, Yu Y, Ziogas A, Berchuck A, Couch FJ, Goode EL, Goodman MT, Monteiro AN, Offit K, Ramus SJ, Risch HA, Schildkraut JM, Thomassen M, Simard J, Easton DF, Jones MR, Chenevix-Trench G, Gayther SA, Antoniou AC, Pharoah PDP

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DOI
10.1038/s41525-025-00529-w
Published
2025 Nov 20
Container
NPJ genomic medicine
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41525-025-00529-w,
  title = {Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer.},
  author = {Barnes DR and Tyrer JP and Dennis J and Leslie G and Bolla MK and Lush M and Aeilts AM and Aittomäki K and Andrieu N and Andrulis IL and Anton-Culver H and Arason A and Arun BK and Balmaña J and Bandera EV and Barkardottir RB and Berger LPV and Berrington de Gonzalez A and Berthet P and Białkowska K and Bjørge L and Blanco AM and Blok MJ and Bobolis KA and Bogdanova NV and Brenton JD and Butz H and Buys SS and Caligo MA and Campbell I and Castillo C and Claes KBM and Colonna SV and Cook LS and Daly MB and Dansonka-Mieszkowska A and de la Hoya M and deFazio A and DePersia A and Ding YC and Doherty JA and Domchek SM and Dörk T and Einbeigi Z and Engel C and Evans DG and Foretova L and Fortner RT and Fostira F and Foti MC and Friedman E and Frone MN and Ganz PA and Gentry-Maharaj A and Glendon G and Godwin AK and González-Neira A and Greene MH and Gronwald J and Guerrieri-Gonzaga A and Hamann U and Hansen TVO and Harris HR and Hauke J and Heitz F and Hogervorst FBL and Hooning MJ and Hopper JL and Huff CD and Huntsman DG and Imyanitov EN and Izatt L and Jakubowska A and James PA and Janavicius R and John EM and Kar S and Karlan BY and Kennedy CJ and Kiemeney LALM and Konstantopoulou I and Kupryjanczyk J and Laitman Y and Lavie O and Lawrenson K and Lester J and Lesueur F and Lopez-Pleguezuelos C and Mai PL and Manoukian S and May T and McNeish IA and Menon U and Milne RL and Modugno F and Mongiovi JM and Montagna M and Moysich KB and Neuhausen SL and Nielsen FC and Noguès C and Oláh E and Olopade OI and Osorio A and Papi L and Pathak H and Pearce CL and Pedersen IS and Peixoto A and Pejovic T and Peng PC and Peshkin BN and Peterlongo P and Powell CB and Prokofyeva D and Pujana MA and Radice P and Rashid MU and Rennert G and Richenberg G and Sandler DP and Sasamoto N and Setiawan VW and Sharma P and Sieh W and Singer CF and Snape K and Sokolenko AP and Soucy P and Southey MC and Stoppa-Lyonnet D and Sutphen R and Sutter C and Tan YY and Teixeira MR and Terry KL and Thomsen LCV and Tischkowitz M and Toland AE and Van Gorp T and Vega A and Velez Edwards DR and Webb PM and Weitzel JN and Wentzensen N and Whittemore AS and Winham SJ and Wu AH and Yadav S and Yu Y and Ziogas A and Berchuck A and Couch FJ and Goode EL and Goodman MT and Monteiro AN and Offit K and Ramus SJ and Risch HA and Schildkraut JM and Thomassen M and Simard J and Easton DF and Jones MR and Chenevix-Trench G and Gayther SA and Antoniou AC and Pharoah PDP},
  year = {2025},
  journal = {NPJ genomic medicine},
  doi = {10.1038/s41525-025-00529-w},
  url = {https://doi.org/10.1038/s41525-025-00529-w}
}

RIS

TY  - JOUR
TI  - Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer.
AU  - Barnes DR
AU  - Tyrer JP
AU  - Dennis J
AU  - Leslie G
AU  - Bolla MK
AU  - Lush M
AU  - Aeilts AM
AU  - Aittomäki K
AU  - Andrieu N
AU  - Andrulis IL
AU  - Anton-Culver H
AU  - Arason A
AU  - Arun BK
AU  - Balmaña J
AU  - Bandera EV
AU  - Barkardottir RB
AU  - Berger LPV
AU  - Berrington de Gonzalez A
AU  - Berthet P
AU  - Białkowska K
AU  - Bjørge L
AU  - Blanco AM
AU  - Blok MJ
AU  - Bobolis KA
AU  - Bogdanova NV
AU  - Brenton JD
AU  - Butz H
AU  - Buys SS
AU  - Caligo MA
AU  - Campbell I
AU  - Castillo C
AU  - Claes KBM
AU  - Colonna SV
AU  - Cook LS
AU  - Daly MB
AU  - Dansonka-Mieszkowska A
AU  - de la Hoya M
AU  - deFazio A
AU  - DePersia A
AU  - Ding YC
AU  - Doherty JA
AU  - Domchek SM
AU  - Dörk T
AU  - Einbeigi Z
AU  - Engel C
AU  - Evans DG
AU  - Foretova L
AU  - Fortner RT
AU  - Fostira F
AU  - Foti MC
AU  - Friedman E
AU  - Frone MN
AU  - Ganz PA
AU  - Gentry-Maharaj A
AU  - Glendon G
AU  - Godwin AK
AU  - González-Neira A
AU  - Greene MH
AU  - Gronwald J
AU  - Guerrieri-Gonzaga A
AU  - Hamann U
AU  - Hansen TVO
AU  - Harris HR
AU  - Hauke J
AU  - Heitz F
AU  - Hogervorst FBL
AU  - Hooning MJ
AU  - Hopper JL
AU  - Huff CD
AU  - Huntsman DG
AU  - Imyanitov EN
AU  - Izatt L
AU  - Jakubowska A
AU  - James PA
AU  - Janavicius R
AU  - John EM
AU  - Kar S
AU  - Karlan BY
AU  - Kennedy CJ
AU  - Kiemeney LALM
AU  - Konstantopoulou I
AU  - Kupryjanczyk J
AU  - Laitman Y
AU  - Lavie O
AU  - Lawrenson K
AU  - Lester J
AU  - Lesueur F
AU  - Lopez-Pleguezuelos C
AU  - Mai PL
AU  - Manoukian S
AU  - May T
AU  - McNeish IA
AU  - Menon U
AU  - Milne RL
AU  - Modugno F
AU  - Mongiovi JM
AU  - Montagna M
AU  - Moysich KB
AU  - Neuhausen SL
AU  - Nielsen FC
AU  - Noguès C
AU  - Oláh E
AU  - Olopade OI
AU  - Osorio A
AU  - Papi L
AU  - Pathak H
AU  - Pearce CL
AU  - Pedersen IS
AU  - Peixoto A
AU  - Pejovic T
AU  - Peng PC
AU  - Peshkin BN
AU  - Peterlongo P
AU  - Powell CB
AU  - Prokofyeva D
AU  - Pujana MA
AU  - Radice P
AU  - Rashid MU
AU  - Rennert G
AU  - Richenberg G
AU  - Sandler DP
AU  - Sasamoto N
AU  - Setiawan VW
AU  - Sharma P
AU  - Sieh W
AU  - Singer CF
AU  - Snape K
AU  - Sokolenko AP
AU  - Soucy P
AU  - Southey MC
AU  - Stoppa-Lyonnet D
AU  - Sutphen R
AU  - Sutter C
AU  - Tan YY
AU  - Teixeira MR
AU  - Terry KL
AU  - Thomsen LCV
AU  - Tischkowitz M
AU  - Toland AE
AU  - Van Gorp T
AU  - Vega A
AU  - Velez Edwards DR
AU  - Webb PM
AU  - Weitzel JN
AU  - Wentzensen N
AU  - Whittemore AS
AU  - Winham SJ
AU  - Wu AH
AU  - Yadav S
AU  - Yu Y
AU  - Ziogas A
AU  - Berchuck A
AU  - Couch FJ
AU  - Goode EL
AU  - Goodman MT
AU  - Monteiro AN
AU  - Offit K
AU  - Ramus SJ
AU  - Risch HA
AU  - Schildkraut JM
AU  - Thomassen M
AU  - Simard J
AU  - Easton DF
AU  - Jones MR
AU  - Chenevix-Trench G
AU  - Gayther SA
AU  - Antoniou AC
AU  - Pharoah PDP
PY  - 2025
JO  - NPJ genomic medicine
DO  - 10.1038/s41525-025-00529-w
UR  - https://doi.org/10.1038/s41525-025-00529-w
ER  - 

APA

DR, B., JP, T., J, D., G, L., MK, B., M, L., AM, A., K, A., N, A., IL, A., H, A., A, A., BK, A., J, B., EV, B., RB, B., LPV, B., A, B. D. G., P, B., K, B., L, B., AM, B., MJ, B., KA, B., NV, B., JD, B., H, B., SS, B., MA, C., I, C., C, C., KBM, C., SV, C., LS, C., MB, D., A, D., M, D. L. H., A, D., A, D., YC, D., JA, D., SM, D., T, D., Z, E., C, E., DG, E., L, F., RT, F., F, F., MC, F., E, F., MN, F., PA, G., A, G., G, G., AK, G., A, G., MH, G., J, G., A, G., U, H., TVO, H., HR, H., J, H., F, H., FBL, H., MJ, H., JL, H., CD, H., DG, H., EN, I., L, I., A, J., PA, J., R, J., EM, J., S, K., BY, K., CJ, K., LALM, K., I, K., J, K., Y, L., O, L., K, L., J, L., F, L., C, L., PL, M., S, M., T, M., IA, M., U, M., RL, M., F, M., JM, M., M, M., KB, M., SL, N., FC, N., C, N., E, O., OI, O., A, O., L, P., H, P., CL, P., IS, P., A, P., T, P., PC, P., BN, P., P, P., CB, P., D, P., MA, P., P, R., MU, R., G, R., G, R., DP, S., N, S., VW, S., P, S., W, S., CF, S., K, S., AP, S., P, S., MC, S., D, S., R, S., C, S., YY, T., MR, T., KL, T., LCV, T., M, T., AE, T., T, V. G., A, V., DR, V. E., PM, W., JN, W., N, W., AS, W., SJ, W., AH, W., S, Y., Y, Y., A, Z., A, B., FJ, C., EL, G., MT, G., AN, M., K, O., SJ, R., HA, R., JM, S., M, T., J, S., DF, E., MR, J., G, C., SA, G., AC, A., & PDP, P. (2025). Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer.. NPJ genomic medicine. https://doi.org/10.1038/s41525-025-00529-w

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