Multi-locus genetic dosage shapes cognitive disease progression in Parkinson’s patients: 15-year meta-analysis of 24 cohorts

Xiaoying Kang, Zechuan Lin, Fatma Zehra Calikusu, Lauren A. Miller, Sofia Soriano, Joseph J. Locascio, Jean-Christophe Corvol, Jodi Maple-Grødem, Yangyi Fan, Kara Mead, Meghan C. Campbell, Alexis Elbaz, Suzanne Lesage, Alexis Brice, Albert Y. Hung, Michael A. Schwarzschild, Michael T. Hayes, Anne-Marie Wills, Todd M. Herrington, Ganqiang Liu, Bernard Ravina, Pille Taba, Sulev Kõks, Tanya Simuni, Lars Forsgren, Carl Counsell, Angus D. Macleod, Thomas G. Beach, Guido Alves, Ole-Bjørn Tysnes, Joel S. Perlmutter, Peter Heutink, Meike Kasten, Brit Mollenhauer, Claudia Trenkwalder, Christine Klein, Dagmar H. Hepp, David Backstrom, Per Svenningsson, Michele T. Hu, Caroline H. Williams-Gray, Roger A. Barker, Unknown, Clemens R. Scherzer

Open source

DOI
10.1038/s41531-026-01367-y
Published
2026-05-14
Container
npj Parkinson's Disease
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s41531-026-01367-y,
  title = {Multi-locus genetic dosage shapes cognitive disease progression in Parkinson’s patients: 15-year meta-analysis of 24 cohorts},
  author = {Xiaoying Kang and Zechuan Lin and Fatma Zehra Calikusu and Lauren A. Miller and Sofia Soriano and Joseph J. Locascio and Jean-Christophe Corvol and Jodi Maple-Grødem and Yangyi Fan and Kara Mead and Meghan C. Campbell and Alexis Elbaz and Suzanne Lesage and Alexis Brice and Albert Y. Hung and Michael A. Schwarzschild and Michael T. Hayes and Anne-Marie Wills and Todd M. Herrington and Ganqiang Liu and Bernard Ravina and Pille Taba and Sulev Kõks and Tanya Simuni and Lars Forsgren and Carl Counsell and Angus D. Macleod and Thomas G. Beach and Guido Alves and Ole-Bjørn Tysnes and Joel S. Perlmutter and Peter Heutink and Meike Kasten and Brit Mollenhauer and Claudia Trenkwalder and Christine Klein and Dagmar H. Hepp and David Backstrom and Per Svenningsson and Michele T. Hu and Caroline H. Williams-Gray and Roger A. Barker and Unknown and Clemens R. Scherzer},
  year = {2026},
  journal = {npj Parkinson's Disease},
  doi = {10.1038/s41531-026-01367-y},
  url = {https://doi.org/10.1038/s41531-026-01367-y}
}

RIS

TY  - JOUR
TI  - Multi-locus genetic dosage shapes cognitive disease progression in Parkinson’s patients: 15-year meta-analysis of 24 cohorts
AU  - Xiaoying Kang
AU  - Zechuan Lin
AU  - Fatma Zehra Calikusu
AU  - Lauren A. Miller
AU  - Sofia Soriano
AU  - Joseph J. Locascio
AU  - Jean-Christophe Corvol
AU  - Jodi Maple-Grødem
AU  - Yangyi Fan
AU  - Kara Mead
AU  - Meghan C. Campbell
AU  - Alexis Elbaz
AU  - Suzanne Lesage
AU  - Alexis Brice
AU  - Albert Y. Hung
AU  - Michael A. Schwarzschild
AU  - Michael T. Hayes
AU  - Anne-Marie Wills
AU  - Todd M. Herrington
AU  - Ganqiang Liu
AU  - Bernard Ravina
AU  - Pille Taba
AU  - Sulev Kõks
AU  - Tanya Simuni
AU  - Lars Forsgren
AU  - Carl Counsell
AU  - Angus D. Macleod
AU  - Thomas G. Beach
AU  - Guido Alves
AU  - Ole-Bjørn Tysnes
AU  - Joel S. Perlmutter
AU  - Peter Heutink
AU  - Meike Kasten
AU  - Brit Mollenhauer
AU  - Claudia Trenkwalder
AU  - Christine Klein
AU  - Dagmar H. Hepp
AU  - David Backstrom
AU  - Per Svenningsson
AU  - Michele T. Hu
AU  - Caroline H. Williams-Gray
AU  - Roger A. Barker
AU  - Unknown
AU  - Clemens R. Scherzer
PY  - 2026
JO  - npj Parkinson's Disease
DO  - 10.1038/s41531-026-01367-y
UR  - https://doi.org/10.1038/s41531-026-01367-y
ER  - 

APA

Kang, X., Lin, Z., Calikusu, F. Z., Miller, L. A., Soriano, S., Locascio, J. J., Corvol, J., Maple-Grødem, J., Fan, Y., Mead, K., Campbell, M. C., Elbaz, A., Lesage, S., Brice, A., Hung, A. Y., Schwarzschild, M. A., Hayes, M. T., Wills, A., Herrington, T. M., Liu, G., Ravina, B., Taba, P., Kõks, S., Simuni, T., Forsgren, L., Counsell, C., Macleod, A. D., Beach, T. G., Alves, G., Tysnes, O., Perlmutter, J. S., Heutink, P., Kasten, M., Mollenhauer, B., Trenkwalder, C., Klein, C., Hepp, D. H., Backstrom, D., Svenningsson, P., Hu, M. T., Williams-Gray, C. H., Barker, R. A., Unknown, & Scherzer, C. R. (2026). Multi-locus genetic dosage shapes cognitive disease progression in Parkinson’s patients: 15-year meta-analysis of 24 cohorts. npj Parkinson's Disease. https://doi.org/10.1038/s41531-026-01367-y

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