Genetic variation in antidiabetic drug targets: associations with Parkinson’s disease risk and age at onset

Katalin Vincze, Agnieszka Szwajda, Alexander Ploner, Robert Karlsson, Xiaoying Kang, Bowen Tang, Chenxi Qin, Cloé Domenighetti, Pierre-Emmanuel Sugier, Ashwin Ashok Kumar Sreelatha, Claudia Schulte, Berta Portugal, Patrick May, Dheeraj Reddy Bobbili, Milena Radivojkov-Blagojevic, Peter Lichtner, Andrew B. Singleton, Dena G. Hernandez, Connor Edsall, George D. Mellick, Alexander Zimprich, Walter Pirker, Ekaterina Rogaeva, Anthony E. Lang, Sulev Koks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugénie Mutez, Kathrin Brockmann, Angela B. Deutschlander, Lena F. Burbulla, Georges M. Hadjigeorgiou, Efthimos Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Hirotaka Matsuo, Akiyoshi Nakayama, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yun Joong Kim, Pierre Kolber, Bart PC Van de Warrenburg, Bastiaan R. Bloem, Mathias Toft, Lasse Pihlstrøm, Leonor Correia Guedes, Joaquim J. Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Caroline Ran, Andrea C. Belin, Andreas Puschmann, Carl E. Clarke, Karen E. Morrison, Manuela Tan, Dimitri Krainc, Matt J. Farrer, Zied Landoulsi, Rejko Kruger, Thomas Gasser, Alexis Elbaz, Manu Sharma, Nancy L. Pedersen, Sofia Carlsson, Sara Hägg, Karin Wirdefeldt, Unknown, Cloé Domenighetti, Pierre-Emmanuel Sugier, Ashwin Ashok Kumar Sreelatha, Claudia Schulte, Berta Portugal, Patrick May, Dheeraj Reddy Bobbili, Milena Radivojkov-Blagojevic, Peter Lichtner, Andrew B. Singleton, Dena G. Hernandez, Connor Edsall, George D. Mellick, Alexander Zimprich, Walter Pirker, Ekaterina Rogaeva, Anthony E. Lang, Sulev Koks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugénie Mutez, Kathrin Brockmann, Angela B. Deutschlander, Lena F. Burbulla, Georges M. Hadjigeorgiou, Efthimos Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Hirotaka Matsuo, Akiyoshi Nakayama, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yun Joong Kim, Pierre Kolber, Bart PC Van de Warrenburg, Bastiaan R. Bloem, Mathias Toft, Lasse Pihlstrøm, Leonor Correia Guedes, Joaquim J. Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Caroline Ran, Andrea C. Belin, Andreas Puschmann, Carl E. Clarke, Karen E. Morrison, Manuela Tan, Dimitri Krainc, Matt J. Farrer, Zied Landoulsi, Rejko Kruger, Thomas Gasser, Alexis Elbaz, Manu Sharma, Karin Wirdefeldt

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DOI: 10.1038/s41531-026-01398-5
Published: 2026-05-28
Container: npj Parkinson's Disease
Publisher: Springer Science and Business Media LLC
Open access: unknown

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BibTeX

@article{allodium:10.1038/s41531-026-01398-5,
title = {Genetic variation in antidiabetic drug targets: associations with Parkinson’s disease risk and age at onset},
author = {Katalin Vincze and Agnieszka Szwajda and Alexander Ploner and Robert Karlsson and Xiaoying Kang and Bowen Tang and Chenxi Qin and Cloé Domenighetti and Pierre-Emmanuel Sugier and Ashwin Ashok Kumar Sreelatha and Claudia Schulte and Berta Portugal and Patrick May and Dheeraj Reddy Bobbili and Milena Radivojkov-Blagojevic and Peter Lichtner and Andrew B. Singleton and Dena G. Hernandez and Connor Edsall and George D. Mellick and Alexander Zimprich and Walter Pirker and Ekaterina Rogaeva and Anthony E. Lang and Sulev Koks and Pille Taba and Suzanne Lesage and Alexis Brice and Jean-Christophe Corvol and Marie-Christine Chartier-Harlin and Eugénie Mutez and Kathrin Brockmann and Angela B. Deutschlander and Lena F. Burbulla and Georges M. Hadjigeorgiou and Efthimos Dardiotis and Leonidas Stefanis and Athina Maria Simitsi and Enza Maria Valente and Simona Petrucci and Letizia Straniero and Anna Zecchinelli and Gianni Pezzoli and Laura Brighina and Carlo Ferrarese and Grazia Annesi and Andrea Quattrone and Monica Gagliardi and Hirotaka Matsuo and Akiyoshi Nakayama and Nobutaka Hattori and Kenya Nishioka and Sun Ju Chung and Yun Joong Kim and Pierre Kolber and Bart PC Van de Warrenburg and Bastiaan R. Bloem and Mathias Toft and Lasse Pihlstrøm and Leonor Correia Guedes and Joaquim J. Ferreira and Soraya Bardien and Jonathan Carr and Eduardo Tolosa and Mario Ezquerra and Pau Pastor and Caroline Ran and Andrea C. Belin and Andreas Puschmann and Carl E. Clarke and Karen E. Morrison and Manuela Tan and Dimitri Krainc and Matt J. Farrer and Zied Landoulsi and Rejko Kruger and Thomas Gasser and Alexis Elbaz and Manu Sharma and Nancy L. Pedersen and Sofia Carlsson and Sara Hägg and Karin Wirdefeldt and Unknown and Cloé Domenighetti and Pierre-Emmanuel Sugier and Ashwin Ashok Kumar Sreelatha and Claudia Schulte and Berta Portugal and Patrick May and Dheeraj Reddy Bobbili and Milena Radivojkov-Blagojevic and Peter Lichtner and Andrew B. Singleton and Dena G. Hernandez and Connor Edsall and George D. Mellick and Alexander Zimprich and Walter Pirker and Ekaterina Rogaeva and Anthony E. Lang and Sulev Koks and Pille Taba and Suzanne Lesage and Alexis Brice and Jean-Christophe Corvol and Marie-Christine Chartier-Harlin and Eugénie Mutez and Kathrin Brockmann and Angela B. Deutschlander and Lena F. Burbulla and Georges M. Hadjigeorgiou and Efthimos Dardiotis and Leonidas Stefanis and Athina Maria Simitsi and Enza Maria Valente and Simona Petrucci and Letizia Straniero and Anna Zecchinelli and Gianni Pezzoli and Laura Brighina and Carlo Ferrarese and Grazia Annesi and Andrea Quattrone and Monica Gagliardi and Hirotaka Matsuo and Akiyoshi Nakayama and Nobutaka Hattori and Kenya Nishioka and Sun Ju Chung and Yun Joong Kim and Pierre Kolber and Bart PC Van de Warrenburg and Bastiaan R. Bloem and Mathias Toft and Lasse Pihlstrøm and Leonor Correia Guedes and Joaquim J. Ferreira and Soraya Bardien and Jonathan Carr and Eduardo Tolosa and Mario Ezquerra and Pau Pastor and Caroline Ran and Andrea C. Belin and Andreas Puschmann and Carl E. Clarke and Karen E. Morrison and Manuela Tan and Dimitri Krainc and Matt J. Farrer and Zied Landoulsi and Rejko Kruger and Thomas Gasser and Alexis Elbaz and Manu Sharma and Karin Wirdefeldt},
year = {2026},
journal = {npj Parkinson's Disease},
doi = {10.1038/s41531-026-01398-5},
url = {https://doi.org/10.1038/s41531-026-01398-5}
}

RIS

TY  - JOUR
TI  - Genetic variation in antidiabetic drug targets: associations with Parkinson’s disease risk and age at onset
AU  - Katalin Vincze
AU  - Agnieszka Szwajda
AU  - Alexander Ploner
AU  - Robert Karlsson
AU  - Xiaoying Kang
AU  - Bowen Tang
AU  - Chenxi Qin
AU  - Cloé Domenighetti
AU  - Pierre-Emmanuel Sugier
AU  - Ashwin Ashok Kumar Sreelatha
AU  - Claudia Schulte
AU  - Berta Portugal
AU  - Patrick May
AU  - Dheeraj Reddy Bobbili
AU  - Milena Radivojkov-Blagojevic
AU  - Peter Lichtner
AU  - Andrew B. Singleton
AU  - Dena G. Hernandez
AU  - Connor Edsall
AU  - George D. Mellick
AU  - Alexander Zimprich
AU  - Walter Pirker
AU  - Ekaterina Rogaeva
AU  - Anthony E. Lang
AU  - Sulev Koks
AU  - Pille Taba
AU  - Suzanne Lesage
AU  - Alexis Brice
AU  - Jean-Christophe Corvol
AU  - Marie-Christine Chartier-Harlin
AU  - Eugénie Mutez
AU  - Kathrin Brockmann
AU  - Angela B. Deutschlander
AU  - Lena F. Burbulla
AU  - Georges M. Hadjigeorgiou
AU  - Efthimos Dardiotis
AU  - Leonidas Stefanis
AU  - Athina Maria Simitsi
AU  - Enza Maria Valente
AU  - Simona Petrucci
AU  - Letizia Straniero
AU  - Anna Zecchinelli
AU  - Gianni Pezzoli
AU  - Laura Brighina
AU  - Carlo Ferrarese
AU  - Grazia Annesi
AU  - Andrea Quattrone
AU  - Monica Gagliardi
AU  - Hirotaka Matsuo
AU  - Akiyoshi Nakayama
AU  - Nobutaka Hattori
AU  - Kenya Nishioka
AU  - Sun Ju Chung
AU  - Yun Joong Kim
AU  - Pierre Kolber
AU  - Bart PC Van de Warrenburg
AU  - Bastiaan R. Bloem
AU  - Mathias Toft
AU  - Lasse Pihlstrøm
AU  - Leonor Correia Guedes
AU  - Joaquim J. Ferreira
AU  - Soraya Bardien
AU  - Jonathan Carr
AU  - Eduardo Tolosa
AU  - Mario Ezquerra
AU  - Pau Pastor
AU  - Caroline Ran
AU  - Andrea C. Belin
AU  - Andreas Puschmann
AU  - Carl E. Clarke
AU  - Karen E. Morrison
AU  - Manuela Tan
AU  - Dimitri Krainc
AU  - Matt J. Farrer
AU  - Zied Landoulsi
AU  - Rejko Kruger
AU  - Thomas Gasser
AU  - Alexis Elbaz
AU  - Manu Sharma
AU  - Nancy L. Pedersen
AU  - Sofia Carlsson
AU  - Sara Hägg
AU  - Karin Wirdefeldt
AU  - Unknown
AU  - Cloé Domenighetti
AU  - Pierre-Emmanuel Sugier
AU  - Ashwin Ashok Kumar Sreelatha
AU  - Claudia Schulte
AU  - Berta Portugal
AU  - Patrick May
AU  - Dheeraj Reddy Bobbili
AU  - Milena Radivojkov-Blagojevic
AU  - Peter Lichtner
AU  - Andrew B. Singleton
AU  - Dena G. Hernandez
AU  - Connor Edsall
AU  - George D. Mellick
AU  - Alexander Zimprich
AU  - Walter Pirker
AU  - Ekaterina Rogaeva
AU  - Anthony E. Lang
AU  - Sulev Koks
AU  - Pille Taba
AU  - Suzanne Lesage
AU  - Alexis Brice
AU  - Jean-Christophe Corvol
AU  - Marie-Christine Chartier-Harlin
AU  - Eugénie Mutez
AU  - Kathrin Brockmann
AU  - Angela B. Deutschlander
AU  - Lena F. Burbulla
AU  - Georges M. Hadjigeorgiou
AU  - Efthimos Dardiotis
AU  - Leonidas Stefanis
AU  - Athina Maria Simitsi
AU  - Enza Maria Valente
AU  - Simona Petrucci
AU  - Letizia Straniero
AU  - Anna Zecchinelli
AU  - Gianni Pezzoli
AU  - Laura Brighina
AU  - Carlo Ferrarese
AU  - Grazia Annesi
AU  - Andrea Quattrone
AU  - Monica Gagliardi
AU  - Hirotaka Matsuo
AU  - Akiyoshi Nakayama
AU  - Nobutaka Hattori
AU  - Kenya Nishioka
AU  - Sun Ju Chung
AU  - Yun Joong Kim
AU  - Pierre Kolber
AU  - Bart PC Van de Warrenburg
AU  - Bastiaan R. Bloem
AU  - Mathias Toft
AU  - Lasse Pihlstrøm
AU  - Leonor Correia Guedes
AU  - Joaquim J. Ferreira
AU  - Soraya Bardien
AU  - Jonathan Carr
AU  - Eduardo Tolosa
AU  - Mario Ezquerra
AU  - Pau Pastor
AU  - Caroline Ran
AU  - Andrea C. Belin
AU  - Andreas Puschmann
AU  - Carl E. Clarke
AU  - Karen E. Morrison
AU  - Manuela Tan
AU  - Dimitri Krainc
AU  - Matt J. Farrer
AU  - Zied Landoulsi
AU  - Rejko Kruger
AU  - Thomas Gasser
AU  - Alexis Elbaz
AU  - Manu Sharma
AU  - Karin Wirdefeldt
PY  - 2026
JO  - npj Parkinson's Disease
DO  - 10.1038/s41531-026-01398-5
UR  - https://doi.org/10.1038/s41531-026-01398-5
ER  -

APA

Vincze, K., Szwajda, A., Ploner, A., Karlsson, R., Kang, X., Tang, B., Qin, C., Domenighetti, C., Sugier, P., Sreelatha, A. A. K., Schulte, C., Portugal, B., May, P., Bobbili, D. R., Radivojkov-Blagojevic, M., Lichtner, P., Singleton, A. B., Hernandez, D. G., Edsall, C., Mellick, G. D., Zimprich, A., Pirker, W., Rogaeva, E., Lang, A. E., Koks, S., Taba, P., Lesage, S., Brice, A., Corvol, J., Chartier-Harlin, M., Mutez, E., Brockmann, K., Deutschlander, A. B., Burbulla, L. F., Hadjigeorgiou, G. M., Dardiotis, E., Stefanis, L., Simitsi, A. M., Valente, E. M., Petrucci, S., Straniero, L., Zecchinelli, A., Pezzoli, G., Brighina, L., Ferrarese, C., Annesi, G., Quattrone, A., Gagliardi, M., Matsuo, H., Nakayama, A., Hattori, N., Nishioka, K., Chung, S. J., Kim, Y. J., Kolber, P., Warrenburg, B. P. V. D., Bloem, B. R., Toft, M., Pihlstrøm, L., Guedes, L. C., Ferreira, J. J., Bardien, S., Carr, J., Tolosa, E., Ezquerra, M., Pastor, P., Ran, C., Belin, A. C., Puschmann, A., Clarke, C. E., Morrison, K. E., Tan, M., Krainc, D., Farrer, M. J., Landoulsi, Z., Kruger, R., Gasser, T., Elbaz, A., Sharma, M., Pedersen, N. L., Carlsson, S., Hägg, S., Wirdefeldt, K., Unknown, Domenighetti, C., Sugier, P., Sreelatha, A. A. K., Schulte, C., Portugal, B., May, P., Bobbili, D. R., Radivojkov-Blagojevic, M., Lichtner, P., Singleton, A. B., Hernandez, D. G., Edsall, C., Mellick, G. D., Zimprich, A., Pirker, W., Rogaeva, E., Lang, A. E., Koks, S., Taba, P., Lesage, S., Brice, A., Corvol, J., Chartier-Harlin, M., Mutez, E., Brockmann, K., Deutschlander, A. B., Burbulla, L. F., Hadjigeorgiou, G. M., Dardiotis, E., Stefanis, L., Simitsi, A. M., Valente, E. M., Petrucci, S., Straniero, L., Zecchinelli, A., Pezzoli, G., Brighina, L., Ferrarese, C., Annesi, G., Quattrone, A., Gagliardi, M., Matsuo, H., Nakayama, A., Hattori, N., Nishioka, K., Chung, S. J., Kim, Y. J., Kolber, P., Warrenburg, B. P. V. D., Bloem, B. R., Toft, M., Pihlstrøm, L., Guedes, L. C., Ferreira, J. J., Bardien, S., Carr, J., Tolosa, E., Ezquerra, M., Pastor, P., Ran, C., Belin, A. C., Puschmann, A., Clarke, C. E., Morrison, K. E., Tan, M., Krainc, D., Farrer, M. J., Landoulsi, Z., Kruger, R., Gasser, T., Elbaz, A., Sharma, M., & Wirdefeldt, K. (2026). Genetic variation in antidiabetic drug targets: associations with Parkinson’s disease risk and age at onset. npj Parkinson's Disease. https://doi.org/10.1038/s41531-026-01398-5

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crossref · retrieved 2026-09-25T19:33:32.652Z