Development of an investigational epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B

Yesseinia Anglero-Rodriguez, Qiang Xiong, Martino Alfredo Cappelluti, Sarah B. Voytek, Glen Acosta, Rayman Choo-Wing, Lenka Hoffman, Arogya Khadka, Jhon A. Medina, Caroline Mugambwa, Chloe Pantano, Sivan Harel, Amber DiPiazza, Sameer Abraham, Erica M. Hildebrand, Ricardo N. Ramirez, Ava Zhai, Xiaoyun Guo, Sahar Abubucker, Chih-Wei Ko, Cristiana Giancarlo, Bradley Niesner, Matteo Conti, Lorena Donnici, Pietro Spinelli, Taesun Eom, Mary S. Morrison, Ari E. Friedland, Raffaele De Francesco, Angelo Lombardo, Vic E. Myer, Aron B. Jaffe, Melissa Bonner, Jennifer L. Marlowe

Open source

DOI: 10.1038/s41551-026-01802-8
Published: 2026-09-21
Container: Nature Biomedical Engineering
Publisher: Springer Science and Business Media LLC
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41551-026-01802-8,
  title = {Development of an investigational epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B},
  author = {Yesseinia Anglero-Rodriguez and Qiang Xiong and Martino Alfredo Cappelluti and Sarah B. Voytek and Glen Acosta and Rayman Choo-Wing and Lenka Hoffman and Arogya Khadka and Jhon A. Medina and Caroline Mugambwa and Chloe Pantano and Sivan Harel and Amber DiPiazza and Sameer Abraham and Erica M. Hildebrand and Ricardo N. Ramirez and Ava Zhai and Xiaoyun Guo and Sahar Abubucker and Chih-Wei Ko and Cristiana Giancarlo and Bradley Niesner and Matteo Conti and Lorena Donnici and Pietro Spinelli and Taesun Eom and Mary S. Morrison and Ari E. Friedland and Raffaele De Francesco and Angelo Lombardo and Vic E. Myer and Aron B. Jaffe and Melissa Bonner and Jennifer L. Marlowe},
  year = {2026},
  journal = {Nature Biomedical Engineering},
  doi = {10.1038/s41551-026-01802-8},
  url = {https://doi.org/10.1038/s41551-026-01802-8}
}

RIS

TY  - JOUR
TI  - Development of an investigational epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B
AU  - Yesseinia Anglero-Rodriguez
AU  - Qiang Xiong
AU  - Martino Alfredo Cappelluti
AU  - Sarah B. Voytek
AU  - Glen Acosta
AU  - Rayman Choo-Wing
AU  - Lenka Hoffman
AU  - Arogya Khadka
AU  - Jhon A. Medina
AU  - Caroline Mugambwa
AU  - Chloe Pantano
AU  - Sivan Harel
AU  - Amber DiPiazza
AU  - Sameer Abraham
AU  - Erica M. Hildebrand
AU  - Ricardo N. Ramirez
AU  - Ava Zhai
AU  - Xiaoyun Guo
AU  - Sahar Abubucker
AU  - Chih-Wei Ko
AU  - Cristiana Giancarlo
AU  - Bradley Niesner
AU  - Matteo Conti
AU  - Lorena Donnici
AU  - Pietro Spinelli
AU  - Taesun Eom
AU  - Mary S. Morrison
AU  - Ari E. Friedland
AU  - Raffaele De Francesco
AU  - Angelo Lombardo
AU  - Vic E. Myer
AU  - Aron B. Jaffe
AU  - Melissa Bonner
AU  - Jennifer L. Marlowe
PY  - 2026
JO  - Nature Biomedical Engineering
DO  - 10.1038/s41551-026-01802-8
UR  - https://doi.org/10.1038/s41551-026-01802-8
ER  -

APA

Anglero-Rodriguez, Y., Xiong, Q., Cappelluti, M. A., Voytek, S. B., Acosta, G., Choo-Wing, R., Hoffman, L., Khadka, A., Medina, J. A., Mugambwa, C., Pantano, C., Harel, S., DiPiazza, A., Abraham, S., Hildebrand, E. M., Ramirez, R. N., Zhai, A., Guo, X., Abubucker, S., Ko, C., Giancarlo, C., Niesner, B., Conti, M., Donnici, L., Spinelli, P., Eom, T., Morrison, M. S., Friedland, A. E., Francesco, R. D., Lombardo, A., Myer, V. E., Jaffe, A. B., Bonner, M., & Marlowe, J. L. (2026). Development of an investigational epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B. Nature Biomedical Engineering. https://doi.org/10.1038/s41551-026-01802-8

Source records

crossref · retrieved 2026-09-25T15:18:49.277Z