Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution.

Diao S, Zou JY, Wang S, Chan JE, Kortlever RM, Poulain N, Ghaddar N, Kim H, Evan GI, Koumenis C, Hatzoglou M, Walter P, Sonenberg N, Le Quesne J, Tammela T, Koromilas AE

Open source

DOI: 10.1038/s41556-026-01991-z
Published: 2026 Jul
Container: Nature cell biology
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41556-026-01991-z,
  title = {Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution.},
  author = {Diao S and Zou JY and Wang S and Chan JE and Kortlever RM and Poulain N and Ghaddar N and Kim H and Evan GI and Koumenis C and Hatzoglou M and Walter P and Sonenberg N and Le Quesne J and Tammela T and Koromilas AE},
  year = {2026},
  journal = {Nature cell biology},
  doi = {10.1038/s41556-026-01991-z},
  url = {https://doi.org/10.1038/s41556-026-01991-z}
}

RIS

TY  - JOUR
TI  - Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution.
AU  - Diao S
AU  - Zou JY
AU  - Wang S
AU  - Chan JE
AU  - Kortlever RM
AU  - Poulain N
AU  - Ghaddar N
AU  - Kim H
AU  - Evan GI
AU  - Koumenis C
AU  - Hatzoglou M
AU  - Walter P
AU  - Sonenberg N
AU  - Le Quesne J
AU  - Tammela T
AU  - Koromilas AE
PY  - 2026
JO  - Nature cell biology
DO  - 10.1038/s41556-026-01991-z
UR  - https://doi.org/10.1038/s41556-026-01991-z
ER  -

APA

S, D., JY, Z., S, W., JE, C., RM, K., N, P., N, G., H, K., GI, E., C, K., M, H., P, W., N, S., J, L. Q., T, T., & AE, K. (2026). Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution.. Nature cell biology. https://doi.org/10.1038/s41556-026-01991-z

Source records

pubmed · retrieved 2026-09-26T12:39:48.790Z