Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19.

Glascock A, Maguire C, Phan HV, Lydon EC, Schaenman J, Calfee CS, Melamed E, Greenland J, Corry DB, Kheradmand F, Baden LR, Sekaly R, McComsey GA, Haddad EK, Cairns CB, Geng LN, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Agudelo Higuita NI, Messer WB, Davis MM, Nadeau KC, Kraft M, Bime C, Erle DJ, Atkinson MA, Brakenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Hoch A, Kim-Schulze S, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Maecker H, Steen H, IMPACC Network, Diray-Arce J, Rouphael N, Kleinstein SH, Jayavelu ND, Reed EF, Levy O, Chu VT, Langelier CR

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DOI: 10.1038/s41564-026-02285-8
Published: 2026 Apr
Container: Nature microbiology
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1038/s41564-026-02285-8,
  title = {Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19.},
  author = {Glascock A and Maguire C and Phan HV and Lydon EC and Schaenman J and Calfee CS and Melamed E and Greenland J and Corry DB and Kheradmand F and Baden LR and Sekaly R and McComsey GA and Haddad EK and Cairns CB and Geng LN and Pulendran B and Fernandez-Sesma A and Simon V and Metcalf JP and Agudelo Higuita NI and Messer WB and Davis MM and Nadeau KC and Kraft M and Bime C and Erle DJ and Atkinson MA and Brakenridge SC and Ehrlich LIR and Montgomery RR and Shaw AC and Hough CL and Hafler DA and Augustine AD and Becker PM and Peters B and Ozonoff A and Hoch A and Kim-Schulze S and Krammer F and Bosinger S and Eckalbar W and Altman MC and Wilson M and Guan L and Maecker H and Steen H and IMPACC Network and Diray-Arce J and Rouphael N and Kleinstein SH and Jayavelu ND and Reed EF and Levy O and Chu VT and Langelier CR},
  year = {2026},
  journal = {Nature microbiology},
  doi = {10.1038/s41564-026-02285-8},
  url = {https://doi.org/10.1038/s41564-026-02285-8}
}

RIS

TY  - JOUR
TI  - Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19.
AU  - Glascock A
AU  - Maguire C
AU  - Phan HV
AU  - Lydon EC
AU  - Schaenman J
AU  - Calfee CS
AU  - Melamed E
AU  - Greenland J
AU  - Corry DB
AU  - Kheradmand F
AU  - Baden LR
AU  - Sekaly R
AU  - McComsey GA
AU  - Haddad EK
AU  - Cairns CB
AU  - Geng LN
AU  - Pulendran B
AU  - Fernandez-Sesma A
AU  - Simon V
AU  - Metcalf JP
AU  - Agudelo Higuita NI
AU  - Messer WB
AU  - Davis MM
AU  - Nadeau KC
AU  - Kraft M
AU  - Bime C
AU  - Erle DJ
AU  - Atkinson MA
AU  - Brakenridge SC
AU  - Ehrlich LIR
AU  - Montgomery RR
AU  - Shaw AC
AU  - Hough CL
AU  - Hafler DA
AU  - Augustine AD
AU  - Becker PM
AU  - Peters B
AU  - Ozonoff A
AU  - Hoch A
AU  - Kim-Schulze S
AU  - Krammer F
AU  - Bosinger S
AU  - Eckalbar W
AU  - Altman MC
AU  - Wilson M
AU  - Guan L
AU  - Maecker H
AU  - Steen H
AU  - IMPACC Network
AU  - Diray-Arce J
AU  - Rouphael N
AU  - Kleinstein SH
AU  - Jayavelu ND
AU  - Reed EF
AU  - Levy O
AU  - Chu VT
AU  - Langelier CR
PY  - 2026
JO  - Nature microbiology
DO  - 10.1038/s41564-026-02285-8
UR  - https://doi.org/10.1038/s41564-026-02285-8
ER  -

APA

A, G., C, M., HV, P., EC, L., J, S., CS, C., E, M., J, G., DB, C., F, K., LR, B., R, S., GA, M., EK, H., CB, C., LN, G., B, P., A, F., V, S., JP, M., NI, A. H., WB, M., MM, D., KC, N., M, K., C, B., DJ, E., MA, A., SC, B., LIR, E., RR, M., AC, S., CL, H., DA, H., AD, A., PM, B., B, P., A, O., A, H., S, K., F, K., S, B., W, E., MC, A., M, W., L, G., H, M., H, S., Network, I., J, D., N, R., SH, K., ND, J., EF, R., O, L., VT, C., & CR, L. (2026). Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19.. Nature microbiology. https://doi.org/10.1038/s41564-026-02285-8

Source records

pubmed · retrieved 2026-09-26T01:46:25.766Z