Identification of constrained sequence elements across 239 primate genomes

Lukas F. K. Kuderna, Jacob C. Ulirsch, Sabrina Rashid, Mohamed Ameen, Laksshman Sundaram, Glenn Hickey, Anthony J. Cox, Hong Gao, Arvind Kumar, Francois Aguet, Matthew J. Christmas, Hiram Clawson, Maximilian Haeussler, Mareike C. Janiak, Martin Kuhlwilm, Joseph D. Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rouselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R. Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S. Chuma, Julie E. Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G. Schraiber, Fabiano R. de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi, Malu Messias, Maria N. F. da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J. Rabarivola, Alphonse Zaramody, Clifford J. Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H. Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D. Keyyu, Sascha Knauf, Minh D. Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C. Kitchener, Dietmar Zinner, Ivo Gut, Amanda D. Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M. D. Beck, Ioannis Karakikes, Kevin C. Wang, Govindhaswamy Umapathy, Christian Roos, Jean P. Boubli, Adam Siepel, Anshul Kundaje, Benedict Paten, Kerstin Lindblad-Toh, Jeffrey Rogers, Tomas Marques Bonet, Kyle Kai-How Farh

Open source

DOI
10.1038/s41586-023-06798-8
Published
2023-11-29
Container
Nature
Publisher
Springer Science and Business Media LLC
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1038/s41586-023-06798-8,
  title = {Identification of constrained sequence elements across 239 primate genomes},
  author = {Lukas F. K. Kuderna and Jacob C. Ulirsch and Sabrina Rashid and Mohamed Ameen and Laksshman Sundaram and Glenn Hickey and Anthony J. Cox and Hong Gao and Arvind Kumar and Francois Aguet and Matthew J. Christmas and Hiram Clawson and Maximilian Haeussler and Mareike C. Janiak and Martin Kuhlwilm and Joseph D. Orkin and Thomas Bataillon and Shivakumara Manu and Alejandro Valenzuela and Juraj Bergman and Marjolaine Rouselle and Felipe Ennes Silva and Lidia Agueda and Julie Blanc and Marta Gut and Dorien de Vries and Ian Goodhead and R. Alan Harris and Muthuswamy Raveendran and Axel Jensen and Idriss S. Chuma and Julie E. Horvath and Christina Hvilsom and David Juan and Peter Frandsen and Joshua G. Schraiber and Fabiano R. de Melo and Fabrício Bertuol and Hazel Byrne and Iracilda Sampaio and Izeni Farias and João Valsecchi and Malu Messias and Maria N. F. da Silva and Mihir Trivedi and Rogerio Rossi and Tomas Hrbek and Nicole Andriaholinirina and Clément J. Rabarivola and Alphonse Zaramody and Clifford J. Jolly and Jane Phillips-Conroy and Gregory Wilkerson and Christian Abee and Joe H. Simmons and Eduardo Fernandez-Duque and Sree Kanthaswamy and Fekadu Shiferaw and Dongdong Wu and Long Zhou and Yong Shao and Guojie Zhang and Julius D. Keyyu and Sascha Knauf and Minh D. Le and Esther Lizano and Stefan Merker and Arcadi Navarro and Tilo Nadler and Chiea Chuen Khor and Jessica Lee and Patrick Tan and Weng Khong Lim and Andrew C. Kitchener and Dietmar Zinner and Ivo Gut and Amanda D. Melin and Katerina Guschanski and Mikkel Heide Schierup and Robin M. D. Beck and Ioannis Karakikes and Kevin C. Wang and Govindhaswamy Umapathy and Christian Roos and Jean P. Boubli and Adam Siepel and Anshul Kundaje and Benedict Paten and Kerstin Lindblad-Toh and Jeffrey Rogers and Tomas Marques Bonet and Kyle Kai-How Farh},
  year = {2023},
  journal = {Nature},
  doi = {10.1038/s41586-023-06798-8},
  url = {https://doi.org/10.1038/s41586-023-06798-8}
}

RIS

TY  - JOUR
TI  - Identification of constrained sequence elements across 239 primate genomes
AU  - Lukas F. K. Kuderna
AU  - Jacob C. Ulirsch
AU  - Sabrina Rashid
AU  - Mohamed Ameen
AU  - Laksshman Sundaram
AU  - Glenn Hickey
AU  - Anthony J. Cox
AU  - Hong Gao
AU  - Arvind Kumar
AU  - Francois Aguet
AU  - Matthew J. Christmas
AU  - Hiram Clawson
AU  - Maximilian Haeussler
AU  - Mareike C. Janiak
AU  - Martin Kuhlwilm
AU  - Joseph D. Orkin
AU  - Thomas Bataillon
AU  - Shivakumara Manu
AU  - Alejandro Valenzuela
AU  - Juraj Bergman
AU  - Marjolaine Rouselle
AU  - Felipe Ennes Silva
AU  - Lidia Agueda
AU  - Julie Blanc
AU  - Marta Gut
AU  - Dorien de Vries
AU  - Ian Goodhead
AU  - R. Alan Harris
AU  - Muthuswamy Raveendran
AU  - Axel Jensen
AU  - Idriss S. Chuma
AU  - Julie E. Horvath
AU  - Christina Hvilsom
AU  - David Juan
AU  - Peter Frandsen
AU  - Joshua G. Schraiber
AU  - Fabiano R. de Melo
AU  - Fabrício Bertuol
AU  - Hazel Byrne
AU  - Iracilda Sampaio
AU  - Izeni Farias
AU  - João Valsecchi
AU  - Malu Messias
AU  - Maria N. F. da Silva
AU  - Mihir Trivedi
AU  - Rogerio Rossi
AU  - Tomas Hrbek
AU  - Nicole Andriaholinirina
AU  - Clément J. Rabarivola
AU  - Alphonse Zaramody
AU  - Clifford J. Jolly
AU  - Jane Phillips-Conroy
AU  - Gregory Wilkerson
AU  - Christian Abee
AU  - Joe H. Simmons
AU  - Eduardo Fernandez-Duque
AU  - Sree Kanthaswamy
AU  - Fekadu Shiferaw
AU  - Dongdong Wu
AU  - Long Zhou
AU  - Yong Shao
AU  - Guojie Zhang
AU  - Julius D. Keyyu
AU  - Sascha Knauf
AU  - Minh D. Le
AU  - Esther Lizano
AU  - Stefan Merker
AU  - Arcadi Navarro
AU  - Tilo Nadler
AU  - Chiea Chuen Khor
AU  - Jessica Lee
AU  - Patrick Tan
AU  - Weng Khong Lim
AU  - Andrew C. Kitchener
AU  - Dietmar Zinner
AU  - Ivo Gut
AU  - Amanda D. Melin
AU  - Katerina Guschanski
AU  - Mikkel Heide Schierup
AU  - Robin M. D. Beck
AU  - Ioannis Karakikes
AU  - Kevin C. Wang
AU  - Govindhaswamy Umapathy
AU  - Christian Roos
AU  - Jean P. Boubli
AU  - Adam Siepel
AU  - Anshul Kundaje
AU  - Benedict Paten
AU  - Kerstin Lindblad-Toh
AU  - Jeffrey Rogers
AU  - Tomas Marques Bonet
AU  - Kyle Kai-How Farh
PY  - 2023
JO  - Nature
DO  - 10.1038/s41586-023-06798-8
UR  - https://doi.org/10.1038/s41586-023-06798-8
ER  - 

APA

Kuderna, L. F. K., Ulirsch, J. C., Rashid, S., Ameen, M., Sundaram, L., Hickey, G., Cox, A. J., Gao, H., Kumar, A., Aguet, F., Christmas, M. J., Clawson, H., Haeussler, M., Janiak, M. C., Kuhlwilm, M., Orkin, J. D., Bataillon, T., Manu, S., Valenzuela, A., Bergman, J., Rouselle, M., Silva, F. E., Agueda, L., Blanc, J., Gut, M., Vries, D. D., Goodhead, I., Harris, R. A., Raveendran, M., Jensen, A., Chuma, I. S., Horvath, J. E., Hvilsom, C., Juan, D., Frandsen, P., Schraiber, J. G., Melo, F. R. D., Bertuol, F., Byrne, H., Sampaio, I., Farias, I., Valsecchi, J., Messias, M., Silva, M. N. F. D., Trivedi, M., Rossi, R., Hrbek, T., Andriaholinirina, N., Rabarivola, C. J., Zaramody, A., Jolly, C. J., Phillips-Conroy, J., Wilkerson, G., Abee, C., Simmons, J. H., Fernandez-Duque, E., Kanthaswamy, S., Shiferaw, F., Wu, D., Zhou, L., Shao, Y., Zhang, G., Keyyu, J. D., Knauf, S., Le, M. D., Lizano, E., Merker, S., Navarro, A., Nadler, T., Khor, C. C., Lee, J., Tan, P., Lim, W. K., Kitchener, A. C., Zinner, D., Gut, I., Melin, A. D., Guschanski, K., Schierup, M. H., Beck, R. M. D., Karakikes, I., Wang, K. C., Umapathy, G., Roos, C., Boubli, J. P., Siepel, A., Kundaje, A., Paten, B., Lindblad-Toh, K., Rogers, J., Bonet, T. M., & Farh, K. K. (2023). Identification of constrained sequence elements across 239 primate genomes. Nature. https://doi.org/10.1038/s41586-023-06798-8

Source records