Translational genomics of osteoarthritis in 1,962,069 individuals.

Hatzikotoulas K, Southam L, Stefansdottir L, Boer CG, McDonald ML, Pett JP, Park YC, Tuerlings M, Mulders R, Barysenka A, Arruda AL, Tragante V, Rocco A, Bittner N, Chen S, Horn S, Srinivasasainagendra V, To K, Katsoula G, Kreitmaier P, Tenghe AMM, Gilly A, Arbeeva L, Chen LG, de Pins AM, Dochtermann D, Henkel C, Höijer J, Ito S, Lind PA, Lukusa-Sawalena B, Minn AKK, Mola-Caminal M, Narita A, Nguyen C, Reimann E, Silberstein MD, Skogholt AH, Tiwari HK, Yau MS, Yue M, Zhao W, Zhou JJ, Alexiadis G, Banasik K, Brunak S, Campbell A, Cheung JTS, Dowsett J, Faquih T, Faul JD, Fei L, Fenstad AM, Funayama T, Gabrielsen ME, Gocho C, Gromov K, Hansen T, Hudjashov G, Ingvarsson T, Johnson JS, Jonsson H, Kakehi S, Karjalainen J, Kasbohm E, Lemmelä S, Lin K, Liu X, Loef M, Mangino M, McCartney D, Millwood IY, Richman J, Roberts MB, Ryan KA, Samartzis D, Shivakumar M, Skou ST, Sugimoto S, Suzuki K, Takuwa H, Teder-Laving M, Thomas L, Tomizuka K, Turman C, Weiss S, Wu TT, Zengini E, Zhang Y, arcOGEN Consortium, ARGO Consortium, DBDS Genomic Consortium, Estonian Biobank Research Team, FinnGen, Genes & Health Research Team, HUNT All-In Pain, Million Veteran Program, Regeneron Genetics Center, Ferreira MAR, Babis G, Baras A, Barker T, Carey DJ, Cheah KSE, Chen Z, Cheung JP, Daly M, de Mutsert R, Eaton CB, Erikstrup C, Furnes ON, Golightly YM, Gudbjartsson DF, Hailer NP, Hayward C, Hochberg MC, Homuth G, Huckins LM, Hveem K, Ikegawa S, Ishijima M, Isomura M, Jones M, Kang JH, Kardia SLR, Kloppenburg M, Kraft P, Kumahashi N, Kuwata S, Lee MTM, Lee PH, Lerner R, Li L, Lietman SA, Lotta L, Lupton MK, Mägi R, Martin NG, McAlindon TE, Medland SE, Michaëlsson K, Mitchell BD, Mook-Kanamori DO, Morris AP, Nabika T, Nagami F, Nelson AE, Ostrowski SR, Palotie A, Pedersen OB, Rosendaal FR, Sakurai-Yageta M, Schmidt CO, Sham PC, Singh JA, Smelser DT, Smith JA, Song YQ, Sørensen E, Tamiya G, Tamura Y, Terao C, Thorleifsson G, Troelsen A, Tsezou A, Uchio Y, Uitterlinden AG, Ullum H, Valdes AM, van Heel DA, Walters RG, Weir DR, Wilkinson JM, Winsvold BS, Yamamoto M, Zwart JA, Stefansson K, Meulenbelt I, Teichmann SA, van Meurs JBJ, Styrkarsdottir U, Zeggini E

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DOI: 10.1038/s41586-025-08771-z
Published: 2025 May
Container: Nature
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1038/s41586-025-08771-z,
  title = {Translational genomics of osteoarthritis in 1,962,069 individuals.},
  author = {Hatzikotoulas K and Southam L and Stefansdottir L and Boer CG and McDonald ML and Pett JP and Park YC and Tuerlings M and Mulders R and Barysenka A and Arruda AL and Tragante V and Rocco A and Bittner N and Chen S and Horn S and Srinivasasainagendra V and To K and Katsoula G and Kreitmaier P and Tenghe AMM and Gilly A and Arbeeva L and Chen LG and de Pins AM and Dochtermann D and Henkel C and Höijer J and Ito S and Lind PA and Lukusa-Sawalena B and Minn AKK and Mola-Caminal M and Narita A and Nguyen C and Reimann E and Silberstein MD and Skogholt AH and Tiwari HK and Yau MS and Yue M and Zhao W and Zhou JJ and Alexiadis G and Banasik K and Brunak S and Campbell A and Cheung JTS and Dowsett J and Faquih T and Faul JD and Fei L and Fenstad AM and Funayama T and Gabrielsen ME and Gocho C and Gromov K and Hansen T and Hudjashov G and Ingvarsson T and Johnson JS and Jonsson H and Kakehi S and Karjalainen J and Kasbohm E and Lemmelä S and Lin K and Liu X and Loef M and Mangino M and McCartney D and Millwood IY and Richman J and Roberts MB and Ryan KA and Samartzis D and Shivakumar M and Skou ST and Sugimoto S and Suzuki K and Takuwa H and Teder-Laving M and Thomas L and Tomizuka K and Turman C and Weiss S and Wu TT and Zengini E and Zhang Y and arcOGEN Consortium and ARGO Consortium and DBDS Genomic Consortium and Estonian Biobank Research Team and FinnGen and Genes \& Health Research Team and HUNT All-In Pain and Million Veteran Program and Regeneron Genetics Center and Ferreira MAR and Babis G and Baras A and Barker T and Carey DJ and Cheah KSE and Chen Z and Cheung JP and Daly M and de Mutsert R and Eaton CB and Erikstrup C and Furnes ON and Golightly YM and Gudbjartsson DF and Hailer NP and Hayward C and Hochberg MC and Homuth G and Huckins LM and Hveem K and Ikegawa S and Ishijima M and Isomura M and Jones M and Kang JH and Kardia SLR and Kloppenburg M and Kraft P and Kumahashi N and Kuwata S and Lee MTM and Lee PH and Lerner R and Li L and Lietman SA and Lotta L and Lupton MK and Mägi R and Martin NG and McAlindon TE and Medland SE and Michaëlsson K and Mitchell BD and Mook-Kanamori DO and Morris AP and Nabika T and Nagami F and Nelson AE and Ostrowski SR and Palotie A and Pedersen OB and Rosendaal FR and Sakurai-Yageta M and Schmidt CO and Sham PC and Singh JA and Smelser DT and Smith JA and Song YQ and Sørensen E and Tamiya G and Tamura Y and Terao C and Thorleifsson G and Troelsen A and Tsezou A and Uchio Y and Uitterlinden AG and Ullum H and Valdes AM and van Heel DA and Walters RG and Weir DR and Wilkinson JM and Winsvold BS and Yamamoto M and Zwart JA and Stefansson K and Meulenbelt I and Teichmann SA and van Meurs JBJ and Styrkarsdottir U and Zeggini E},
  year = {2025},
  journal = {Nature},
  doi = {10.1038/s41586-025-08771-z},
  url = {https://doi.org/10.1038/s41586-025-08771-z}
}

RIS

TY  - JOUR
TI  - Translational genomics of osteoarthritis in 1,962,069 individuals.
AU  - Hatzikotoulas K
AU  - Southam L
AU  - Stefansdottir L
AU  - Boer CG
AU  - McDonald ML
AU  - Pett JP
AU  - Park YC
AU  - Tuerlings M
AU  - Mulders R
AU  - Barysenka A
AU  - Arruda AL
AU  - Tragante V
AU  - Rocco A
AU  - Bittner N
AU  - Chen S
AU  - Horn S
AU  - Srinivasasainagendra V
AU  - To K
AU  - Katsoula G
AU  - Kreitmaier P
AU  - Tenghe AMM
AU  - Gilly A
AU  - Arbeeva L
AU  - Chen LG
AU  - de Pins AM
AU  - Dochtermann D
AU  - Henkel C
AU  - Höijer J
AU  - Ito S
AU  - Lind PA
AU  - Lukusa-Sawalena B
AU  - Minn AKK
AU  - Mola-Caminal M
AU  - Narita A
AU  - Nguyen C
AU  - Reimann E
AU  - Silberstein MD
AU  - Skogholt AH
AU  - Tiwari HK
AU  - Yau MS
AU  - Yue M
AU  - Zhao W
AU  - Zhou JJ
AU  - Alexiadis G
AU  - Banasik K
AU  - Brunak S
AU  - Campbell A
AU  - Cheung JTS
AU  - Dowsett J
AU  - Faquih T
AU  - Faul JD
AU  - Fei L
AU  - Fenstad AM
AU  - Funayama T
AU  - Gabrielsen ME
AU  - Gocho C
AU  - Gromov K
AU  - Hansen T
AU  - Hudjashov G
AU  - Ingvarsson T
AU  - Johnson JS
AU  - Jonsson H
AU  - Kakehi S
AU  - Karjalainen J
AU  - Kasbohm E
AU  - Lemmelä S
AU  - Lin K
AU  - Liu X
AU  - Loef M
AU  - Mangino M
AU  - McCartney D
AU  - Millwood IY
AU  - Richman J
AU  - Roberts MB
AU  - Ryan KA
AU  - Samartzis D
AU  - Shivakumar M
AU  - Skou ST
AU  - Sugimoto S
AU  - Suzuki K
AU  - Takuwa H
AU  - Teder-Laving M
AU  - Thomas L
AU  - Tomizuka K
AU  - Turman C
AU  - Weiss S
AU  - Wu TT
AU  - Zengini E
AU  - Zhang Y
AU  - arcOGEN Consortium
AU  - ARGO Consortium
AU  - DBDS Genomic Consortium
AU  - Estonian Biobank Research Team
AU  - FinnGen
AU  - Genes & Health Research Team
AU  - HUNT All-In Pain
AU  - Million Veteran Program
AU  - Regeneron Genetics Center
AU  - Ferreira MAR
AU  - Babis G
AU  - Baras A
AU  - Barker T
AU  - Carey DJ
AU  - Cheah KSE
AU  - Chen Z
AU  - Cheung JP
AU  - Daly M
AU  - de Mutsert R
AU  - Eaton CB
AU  - Erikstrup C
AU  - Furnes ON
AU  - Golightly YM
AU  - Gudbjartsson DF
AU  - Hailer NP
AU  - Hayward C
AU  - Hochberg MC
AU  - Homuth G
AU  - Huckins LM
AU  - Hveem K
AU  - Ikegawa S
AU  - Ishijima M
AU  - Isomura M
AU  - Jones M
AU  - Kang JH
AU  - Kardia SLR
AU  - Kloppenburg M
AU  - Kraft P
AU  - Kumahashi N
AU  - Kuwata S
AU  - Lee MTM
AU  - Lee PH
AU  - Lerner R
AU  - Li L
AU  - Lietman SA
AU  - Lotta L
AU  - Lupton MK
AU  - Mägi R
AU  - Martin NG
AU  - McAlindon TE
AU  - Medland SE
AU  - Michaëlsson K
AU  - Mitchell BD
AU  - Mook-Kanamori DO
AU  - Morris AP
AU  - Nabika T
AU  - Nagami F
AU  - Nelson AE
AU  - Ostrowski SR
AU  - Palotie A
AU  - Pedersen OB
AU  - Rosendaal FR
AU  - Sakurai-Yageta M
AU  - Schmidt CO
AU  - Sham PC
AU  - Singh JA
AU  - Smelser DT
AU  - Smith JA
AU  - Song YQ
AU  - Sørensen E
AU  - Tamiya G
AU  - Tamura Y
AU  - Terao C
AU  - Thorleifsson G
AU  - Troelsen A
AU  - Tsezou A
AU  - Uchio Y
AU  - Uitterlinden AG
AU  - Ullum H
AU  - Valdes AM
AU  - van Heel DA
AU  - Walters RG
AU  - Weir DR
AU  - Wilkinson JM
AU  - Winsvold BS
AU  - Yamamoto M
AU  - Zwart JA
AU  - Stefansson K
AU  - Meulenbelt I
AU  - Teichmann SA
AU  - van Meurs JBJ
AU  - Styrkarsdottir U
AU  - Zeggini E
PY  - 2025
JO  - Nature
DO  - 10.1038/s41586-025-08771-z
UR  - https://doi.org/10.1038/s41586-025-08771-z
ER  -

APA

K, H., L, S., L, S., CG, B., ML, M., JP, P., YC, P., M, T., R, M., A, B., AL, A., V, T., A, R., N, B., S, C., S, H., V, S., K, T., G, K., P, K., AMM, T., A, G., L, A., LG, C., AM, D. P., D, D., C, H., J, H., S, I., PA, L., B, L., AKK, M., M, M., A, N., C, N., E, R., MD, S., AH, S., HK, T., MS, Y., M, Y., W, Z., JJ, Z., G, A., K, B., S, B., A, C., JTS, C., J, D., T, F., JD, F., L, F., AM, F., T, F., ME, G., C, G., K, G., T, H., G, H., T, I., JS, J., H, J., S, K., J, K., E, K., S, L., K, L., X, L., M, L., M, M., D, M., IY, M., J, R., MB, R., KA, R., D, S., M, S., ST, S., S, S., K, S., H, T., M, T., L, T., K, T., C, T., S, W., TT, W., E, Z., Y, Z., Consortium, A., Consortium, A., Consortium, D. G., Team, E. B. R., FinnGen, Team, G. &. H. R., Pain, H. A., Program, M. V., Center, R. G., MAR, F., G, B., A, B., T, B., DJ, C., KSE, C., Z, C., JP, C., M, D., R, D. M., CB, E., C, E., ON, F., YM, G., DF, G., NP, H., C, H., MC, H., G, H., LM, H., K, H., S, I., M, I., M, I., M, J., JH, K., SLR, K., M, K., P, K., N, K., S, K., MTM, L., PH, L., R, L., L, L., SA, L., L, L., MK, L., R, M., NG, M., TE, M., SE, M., K, M., BD, M., DO, M., AP, M., T, N., F, N., AE, N., SR, O., A, P., OB, P., FR, R., M, S., CO, S., PC, S., JA, S., DT, S., JA, S., YQ, S., E, S., G, T., Y, T., C, T., G, T., A, T., A, T., Y, U., AG, U., H, U., AM, V., DA, V. H., RG, W., DR, W., JM, W., BS, W., M, Y., JA, Z., K, S., I, M., SA, T., JBJ, V. M., U, S., & E, Z. (2025). Translational genomics of osteoarthritis in 1,962,069 individuals.. Nature. https://doi.org/10.1038/s41586-025-08771-z

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pubmed · retrieved 2026-09-26T18:55:15.038Z