An encyclopedia of human enhancer-gene regulatory interactions.

Gschwind AR, Mualim KS, Karbalayghareh A, Sheth MU, Dey KK, Jagoda E, Nurtdinov RN, Xi W, Tan AS, Galante J, Jones H, Ma XR, Yao D, Amgalan D, Ray J, Munger CJ, Nasser J, Avsec Ž, James BT, Shamim MS, Durand NC, Rao SSP, Mahajan R, Doughty BR, Andreeva K, Ulirsch JC, Fan K, Perez EM, Nguyen TC, Kelley DR, Finucane HK, Moore JE, Weng Z, Kellis M, Bassik MC, Ustun B, Price AL, Beer MA, Guigó R, Stamatoyannopoulos JA, Lieberman Aiden E, Greenleaf WJ, Leslie CS, Steinmetz LM, Kundaje A, Engreitz JM

Open source

DOI: 10.1038/s41586-026-10781-4
Published: 2026 Sep
Container: Nature
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41586-026-10781-4,
  title = {An encyclopedia of human enhancer-gene regulatory interactions.},
  author = {Gschwind AR and Mualim KS and Karbalayghareh A and Sheth MU and Dey KK and Jagoda E and Nurtdinov RN and Xi W and Tan AS and Galante J and Jones H and Ma XR and Yao D and Amgalan D and Ray J and Munger CJ and Nasser J and Avsec Ž and James BT and Shamim MS and Durand NC and Rao SSP and Mahajan R and Doughty BR and Andreeva K and Ulirsch JC and Fan K and Perez EM and Nguyen TC and Kelley DR and Finucane HK and Moore JE and Weng Z and Kellis M and Bassik MC and Ustun B and Price AL and Beer MA and Guigó R and Stamatoyannopoulos JA and Lieberman Aiden E and Greenleaf WJ and Leslie CS and Steinmetz LM and Kundaje A and Engreitz JM},
  year = {2026},
  journal = {Nature},
  doi = {10.1038/s41586-026-10781-4},
  url = {https://doi.org/10.1038/s41586-026-10781-4}
}

RIS

TY  - JOUR
TI  - An encyclopedia of human enhancer-gene regulatory interactions.
AU  - Gschwind AR
AU  - Mualim KS
AU  - Karbalayghareh A
AU  - Sheth MU
AU  - Dey KK
AU  - Jagoda E
AU  - Nurtdinov RN
AU  - Xi W
AU  - Tan AS
AU  - Galante J
AU  - Jones H
AU  - Ma XR
AU  - Yao D
AU  - Amgalan D
AU  - Ray J
AU  - Munger CJ
AU  - Nasser J
AU  - Avsec Ž
AU  - James BT
AU  - Shamim MS
AU  - Durand NC
AU  - Rao SSP
AU  - Mahajan R
AU  - Doughty BR
AU  - Andreeva K
AU  - Ulirsch JC
AU  - Fan K
AU  - Perez EM
AU  - Nguyen TC
AU  - Kelley DR
AU  - Finucane HK
AU  - Moore JE
AU  - Weng Z
AU  - Kellis M
AU  - Bassik MC
AU  - Ustun B
AU  - Price AL
AU  - Beer MA
AU  - Guigó R
AU  - Stamatoyannopoulos JA
AU  - Lieberman Aiden E
AU  - Greenleaf WJ
AU  - Leslie CS
AU  - Steinmetz LM
AU  - Kundaje A
AU  - Engreitz JM
PY  - 2026
JO  - Nature
DO  - 10.1038/s41586-026-10781-4
UR  - https://doi.org/10.1038/s41586-026-10781-4
ER  -

APA

AR, G., KS, M., A, K., MU, S., KK, D., E, J., RN, N., W, X., AS, T., J, G., H, J., XR, M., D, Y., D, A., J, R., CJ, M., J, N., Ž, A., BT, J., MS, S., NC, D., SSP, R., R, M., BR, D., K, A., JC, U., K, F., EM, P., TC, N., DR, K., HK, F., JE, M., Z, W., M, K., MC, B., B, U., AL, P., MA, B., R, G., JA, S., E, L. A., WJ, G., CS, L., LM, S., A, K., & JM, E. (2026). An encyclopedia of human enhancer-gene regulatory interactions.. Nature. https://doi.org/10.1038/s41586-026-10781-4

Source records

pubmed · retrieved 2026-09-25T19:31:55.744Z