A tumour-derived organoid biobank maps cancer gene dependencies

C. Herranz-Ors, S. G. Bhosle, A. E. Beck, J. G. R. Gilbert, G. Picco, J. Espejo Valle-Inclan, F. Muyas, S. Valentini, A. E. Andres, R. Ansari, S. Barthorpe, G. Battarbee, C. M. Beaver, S. Brocklesby, J. Cantwell, C. A. Collins, J. Davis, H. G. Dimitrova, J. Doran, E. Efendi, K. Evans, M. Fekry, T. A. Fowler, M. Garcia-Casado, J. A. T. Griffiths, C. Hall, R. Hamer, C. Hardy, Z. Hewitson, E. Hitch, L. Holland, D. A. Jackson, N. Joshi, A. Kavasakali, L. Letchford, H. B. Lightfoot, H. Lingala, I. Mali, K. May, T. Mironenko, J. Morris, C. Pacini, S. Price, G. Robert-Tissot, H. A. Rogers, J. V. Smith, K. Smith, E. Souster, W. J. Spence, F. Thomas, S. F. Vieira, S. Walker, G. Alfonsin, H. Bermingham, H. Coles, D. P. Ennis, A. Freeman, G. Giannone, N. Grehan, E. A. Griffiths, J. Hall, S. L. Lee, E. Y. L. Leung, C. Loreno, C. Millington, A. Mirnezami, B. Nutzinger, K. Orzechowska, C. M. A. Pinna, A. M. Redmond, K. Roberts, S. Roy, D. A. Sanders, P. Taniere, M. Vias, K. Wanigasooriya, Unknown, P. A. W. Edwards, S. Abbas, E. C. Smyth, M. O’Donovan, A. Miremadi, S. Malhotra, M. Tripathi, C. Cheah, M. Eldridge, M. Secrier, G. Devonshire, S. Jammula, J. Davies, C. Crichton, N. Carroll, R. H. Hardwick, P. Safranek, A. Hindmarsh, V. Sujendran, S. J. Hayes, Y. Ang, A. Sharrocks, S. R. Preston, I. Bagwan, V. Save, R. J. E. Skipworth, J. R. O’Neill, O. Tucker, A. Beggs, S. Puig, G. Contino, B. L. Grace, J. Lagergren, J. Gossage, A. Davies, F. Chang, U. Mahadeva, V. Goh, F. D. Ciccarelli, G. Sanders, D. Chan, E. Cheong, B. Kumar, L. Sreedharan, S. L. Parsons, I. Soomro, P. Kaye, J. Saunders, L. Lovat, R. Haidry, M. Scott, S. Sothi, G. B. Hanna, C. J. Peters, K. Moorthy, A. Grabowska, R. Turkington, D. McManus, H. Coleman, R. D. Petty, F. Bartlett, T. D. L. Crosby, M. R. Stratton, L. M. Staudt, U. McDermott, J. D. Brenton, I. A. McNeish, A. Biankin, O. J. Sansom, I. Cortes-Ciriano, T. J. Underwood, R. C. Fitzgerald, A. D. Beggs, H. E. Francies, M. J. Garnett

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DOI: 10.1038/s41586-026-10830-y
Published: 2026-08-05
Container: Nature
Publisher: Springer Science and Business Media LLC
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Cite this work

BibTeX

@article{allodium:10.1038/s41586-026-10830-y,
title = {A tumour-derived organoid biobank maps cancer gene dependencies},
author = {C. Herranz-Ors and S. G. Bhosle and A. E. Beck and J. G. R. Gilbert and G. Picco and J. Espejo Valle-Inclan and F. Muyas and S. Valentini and A. E. Andres and R. Ansari and S. Barthorpe and G. Battarbee and C. M. Beaver and S. Brocklesby and J. Cantwell and C. A. Collins and J. Davis and H. G. Dimitrova and J. Doran and E. Efendi and K. Evans and M. Fekry and T. A. Fowler and M. Garcia-Casado and J. A. T. Griffiths and C. Hall and R. Hamer and C. Hardy and Z. Hewitson and E. Hitch and L. Holland and D. A. Jackson and N. Joshi and A. Kavasakali and L. Letchford and H. B. Lightfoot and H. Lingala and I. Mali and K. May and T. Mironenko and J. Morris and C. Pacini and S. Price and G. Robert-Tissot and H. A. Rogers and J. V. Smith and K. Smith and E. Souster and W. J. Spence and F. Thomas and S. F. Vieira and S. Walker and G. Alfonsin and H. Bermingham and H. Coles and D. P. Ennis and A. Freeman and G. Giannone and N. Grehan and E. A. Griffiths and J. Hall and S. L. Lee and E. Y. L. Leung and C. Loreno and C. Millington and A. Mirnezami and B. Nutzinger and K. Orzechowska and C. M. A. Pinna and A. M. Redmond and K. Roberts and S. Roy and D. A. Sanders and P. Taniere and M. Vias and K. Wanigasooriya and Unknown and P. A. W. Edwards and S. Abbas and E. C. Smyth and M. O’Donovan and A. Miremadi and S. Malhotra and M. Tripathi and C. Cheah and M. Eldridge and M. Secrier and G. Devonshire and S. Jammula and J. Davies and C. Crichton and N. Carroll and R. H. Hardwick and P. Safranek and A. Hindmarsh and V. Sujendran and S. J. Hayes and Y. Ang and A. Sharrocks and S. R. Preston and I. Bagwan and V. Save and R. J. E. Skipworth and J. R. O’Neill and O. Tucker and A. Beggs and S. Puig and G. Contino and B. L. Grace and J. Lagergren and J. Gossage and A. Davies and F. Chang and U. Mahadeva and V. Goh and F. D. Ciccarelli and G. Sanders and D. Chan and E. Cheong and B. Kumar and L. Sreedharan and S. L. Parsons and I. Soomro and P. Kaye and J. Saunders and L. Lovat and R. Haidry and M. Scott and S. Sothi and G. B. Hanna and C. J. Peters and K. Moorthy and A. Grabowska and R. Turkington and D. McManus and H. Coleman and R. D. Petty and F. Bartlett and T. D. L. Crosby and M. R. Stratton and L. M. Staudt and U. McDermott and J. D. Brenton and I. A. McNeish and A. Biankin and O. J. Sansom and I. Cortes-Ciriano and T. J. Underwood and R. C. Fitzgerald and A. D. Beggs and H. E. Francies and M. J. Garnett},
year = {2026},
journal = {Nature},
doi = {10.1038/s41586-026-10830-y},
url = {https://doi.org/10.1038/s41586-026-10830-y}
}

RIS

TY  - JOUR
TI  - A tumour-derived organoid biobank maps cancer gene dependencies
AU  - C. Herranz-Ors
AU  - S. G. Bhosle
AU  - A. E. Beck
AU  - J. G. R. Gilbert
AU  - G. Picco
AU  - J. Espejo Valle-Inclan
AU  - F. Muyas
AU  - S. Valentini
AU  - A. E. Andres
AU  - R. Ansari
AU  - S. Barthorpe
AU  - G. Battarbee
AU  - C. M. Beaver
AU  - S. Brocklesby
AU  - J. Cantwell
AU  - C. A. Collins
AU  - J. Davis
AU  - H. G. Dimitrova
AU  - J. Doran
AU  - E. Efendi
AU  - K. Evans
AU  - M. Fekry
AU  - T. A. Fowler
AU  - M. Garcia-Casado
AU  - J. A. T. Griffiths
AU  - C. Hall
AU  - R. Hamer
AU  - C. Hardy
AU  - Z. Hewitson
AU  - E. Hitch
AU  - L. Holland
AU  - D. A. Jackson
AU  - N. Joshi
AU  - A. Kavasakali
AU  - L. Letchford
AU  - H. B. Lightfoot
AU  - H. Lingala
AU  - I. Mali
AU  - K. May
AU  - T. Mironenko
AU  - J. Morris
AU  - C. Pacini
AU  - S. Price
AU  - G. Robert-Tissot
AU  - H. A. Rogers
AU  - J. V. Smith
AU  - K. Smith
AU  - E. Souster
AU  - W. J. Spence
AU  - F. Thomas
AU  - S. F. Vieira
AU  - S. Walker
AU  - G. Alfonsin
AU  - H. Bermingham
AU  - H. Coles
AU  - D. P. Ennis
AU  - A. Freeman
AU  - G. Giannone
AU  - N. Grehan
AU  - E. A. Griffiths
AU  - J. Hall
AU  - S. L. Lee
AU  - E. Y. L. Leung
AU  - C. Loreno
AU  - C. Millington
AU  - A. Mirnezami
AU  - B. Nutzinger
AU  - K. Orzechowska
AU  - C. M. A. Pinna
AU  - A. M. Redmond
AU  - K. Roberts
AU  - S. Roy
AU  - D. A. Sanders
AU  - P. Taniere
AU  - M. Vias
AU  - K. Wanigasooriya
AU  - Unknown
AU  - P. A. W. Edwards
AU  - S. Abbas
AU  - E. C. Smyth
AU  - M. O’Donovan
AU  - A. Miremadi
AU  - S. Malhotra
AU  - M. Tripathi
AU  - C. Cheah
AU  - M. Eldridge
AU  - M. Secrier
AU  - G. Devonshire
AU  - S. Jammula
AU  - J. Davies
AU  - C. Crichton
AU  - N. Carroll
AU  - R. H. Hardwick
AU  - P. Safranek
AU  - A. Hindmarsh
AU  - V. Sujendran
AU  - S. J. Hayes
AU  - Y. Ang
AU  - A. Sharrocks
AU  - S. R. Preston
AU  - I. Bagwan
AU  - V. Save
AU  - R. J. E. Skipworth
AU  - J. R. O’Neill
AU  - O. Tucker
AU  - A. Beggs
AU  - S. Puig
AU  - G. Contino
AU  - B. L. Grace
AU  - J. Lagergren
AU  - J. Gossage
AU  - A. Davies
AU  - F. Chang
AU  - U. Mahadeva
AU  - V. Goh
AU  - F. D. Ciccarelli
AU  - G. Sanders
AU  - D. Chan
AU  - E. Cheong
AU  - B. Kumar
AU  - L. Sreedharan
AU  - S. L. Parsons
AU  - I. Soomro
AU  - P. Kaye
AU  - J. Saunders
AU  - L. Lovat
AU  - R. Haidry
AU  - M. Scott
AU  - S. Sothi
AU  - G. B. Hanna
AU  - C. J. Peters
AU  - K. Moorthy
AU  - A. Grabowska
AU  - R. Turkington
AU  - D. McManus
AU  - H. Coleman
AU  - R. D. Petty
AU  - F. Bartlett
AU  - T. D. L. Crosby
AU  - M. R. Stratton
AU  - L. M. Staudt
AU  - U. McDermott
AU  - J. D. Brenton
AU  - I. A. McNeish
AU  - A. Biankin
AU  - O. J. Sansom
AU  - I. Cortes-Ciriano
AU  - T. J. Underwood
AU  - R. C. Fitzgerald
AU  - A. D. Beggs
AU  - H. E. Francies
AU  - M. J. Garnett
PY  - 2026
JO  - Nature
DO  - 10.1038/s41586-026-10830-y
UR  - https://doi.org/10.1038/s41586-026-10830-y
ER  -

APA

Herranz-Ors, C., Bhosle, S. G., Beck, A. E., Gilbert, J. G. R., Picco, G., Valle-Inclan, J. E., Muyas, F., Valentini, S., Andres, A. E., Ansari, R., Barthorpe, S., Battarbee, G., Beaver, C. M., Brocklesby, S., Cantwell, J., Collins, C. A., Davis, J., Dimitrova, H. G., Doran, J., Efendi, E., Evans, K., Fekry, M., Fowler, T. A., Garcia-Casado, M., Griffiths, J. A. T., Hall, C., Hamer, R., Hardy, C., Hewitson, Z., Hitch, E., Holland, L., Jackson, D. A., Joshi, N., Kavasakali, A., Letchford, L., Lightfoot, H. B., Lingala, H., Mali, I., May, K., Mironenko, T., Morris, J., Pacini, C., Price, S., Robert-Tissot, G., Rogers, H. A., Smith, J. V., Smith, K., Souster, E., Spence, W. J., Thomas, F., Vieira, S. F., Walker, S., Alfonsin, G., Bermingham, H., Coles, H., Ennis, D. P., Freeman, A., Giannone, G., Grehan, N., Griffiths, E. A., Hall, J., Lee, S. L., Leung, E. Y. L., Loreno, C., Millington, C., Mirnezami, A., Nutzinger, B., Orzechowska, K., Pinna, C. M. A., Redmond, A. M., Roberts, K., Roy, S., Sanders, D. A., Taniere, P., Vias, M., Wanigasooriya, K., Unknown, Edwards, P. A. W., Abbas, S., Smyth, E. C., O’Donovan, M., Miremadi, A., Malhotra, S., Tripathi, M., Cheah, C., Eldridge, M., Secrier, M., Devonshire, G., Jammula, S., Davies, J., Crichton, C., Carroll, N., Hardwick, R. H., Safranek, P., Hindmarsh, A., Sujendran, V., Hayes, S. J., Ang, Y., Sharrocks, A., Preston, S. R., Bagwan, I., Save, V., Skipworth, R. J. E., O’Neill, J. R., Tucker, O., Beggs, A., Puig, S., Contino, G., Grace, B. L., Lagergren, J., Gossage, J., Davies, A., Chang, F., Mahadeva, U., Goh, V., Ciccarelli, F. D., Sanders, G., Chan, D., Cheong, E., Kumar, B., Sreedharan, L., Parsons, S. L., Soomro, I., Kaye, P., Saunders, J., Lovat, L., Haidry, R., Scott, M., Sothi, S., Hanna, G. B., Peters, C. J., Moorthy, K., Grabowska, A., Turkington, R., McManus, D., Coleman, H., Petty, R. D., Bartlett, F., Crosby, T. D. L., Stratton, M. R., Staudt, L. M., McDermott, U., Brenton, J. D., McNeish, I. A., Biankin, A., Sansom, O. J., Cortes-Ciriano, I., Underwood, T. J., Fitzgerald, R. C., Beggs, A. D., Francies, H. E., & Garnett, M. J. (2026). A tumour-derived organoid biobank maps cancer gene dependencies. Nature. https://doi.org/10.1038/s41586-026-10830-y

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crossref · retrieved 2026-09-26T04:48:00.299Z