An AI-enabled structural atlas decodes kinase specificity across the human proteome

David R. Vanderwall, Edward L. Huttlin, Julian Mintseris, Tomer M. Yaron-Barir, Jared L. Johnson, Kevin D. Dong, Alex J. Bott, Yuchen He, Christina B. Schroeter, Geordon A. Frere, Mohamed Uduman, Harin Lee, Sean Landry, Sean A. Beausoleil, Joao A. Paulo, Lewis C. Cantley, Steven P. Gygi

Open source

DOI
10.1038/s41587-026-03239-5
Published
2026-07-29
Container
Nature Biotechnology
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s41587-026-03239-5,
  title = {An AI-enabled structural atlas decodes kinase specificity across the human proteome},
  author = {David R. Vanderwall and Edward L. Huttlin and Julian Mintseris and Tomer M. Yaron-Barir and Jared L. Johnson and Kevin D. Dong and Alex J. Bott and Yuchen He and Christina B. Schroeter and Geordon A. Frere and Mohamed Uduman and Harin Lee and Sean Landry and Sean A. Beausoleil and Joao A. Paulo and Lewis C. Cantley and Steven P. Gygi},
  year = {2026},
  journal = {Nature Biotechnology},
  doi = {10.1038/s41587-026-03239-5},
  url = {https://doi.org/10.1038/s41587-026-03239-5}
}

RIS

TY  - JOUR
TI  - An AI-enabled structural atlas decodes kinase specificity across the human proteome
AU  - David R. Vanderwall
AU  - Edward L. Huttlin
AU  - Julian Mintseris
AU  - Tomer M. Yaron-Barir
AU  - Jared L. Johnson
AU  - Kevin D. Dong
AU  - Alex J. Bott
AU  - Yuchen He
AU  - Christina B. Schroeter
AU  - Geordon A. Frere
AU  - Mohamed Uduman
AU  - Harin Lee
AU  - Sean Landry
AU  - Sean A. Beausoleil
AU  - Joao A. Paulo
AU  - Lewis C. Cantley
AU  - Steven P. Gygi
PY  - 2026
JO  - Nature Biotechnology
DO  - 10.1038/s41587-026-03239-5
UR  - https://doi.org/10.1038/s41587-026-03239-5
ER  - 

APA

Vanderwall, D. R., Huttlin, E. L., Mintseris, J., Yaron-Barir, T. M., Johnson, J. L., Dong, K. D., Bott, A. J., He, Y., Schroeter, C. B., Frere, G. A., Uduman, M., Lee, H., Landry, S., Beausoleil, S. A., Paulo, J. A., Cantley, L. C., & Gygi, S. P. (2026). An AI-enabled structural atlas decodes kinase specificity across the human proteome. Nature Biotechnology. https://doi.org/10.1038/s41587-026-03239-5

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