Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells

Hyuncheol Jung, Pascal Devant, Carter Ching, Mineto Ota, Emma Dann, Ronghui Zhu, Chandrima Modak, Ana Vasquez-Ibarra, Jennifer R. Hamilton, Zachary Steinhart, Wayne Ngo, Luis Sandoval, Jae Hyung Jung, Jae Hyun J. Lee, Da Xu, Meirui An, Esha Urs, Peixin Amy Chen, Vincent Allain, Takuya Tada, Luke A. Gilbert, Brian R. Shy, Jonathan K. Pritchard, James K. Nuñez, Nathaniel R. Landau, David R. Liu, Justin Eyquem, Jennifer A. Doudna, Alexander Marson, Julia Carnevale

Open source

DOI: 10.1038/s41587-026-03258-2
Published: 2026-08-17
Container: Nature Biotechnology
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41587-026-03258-2,
  title = {Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells},
  author = {Hyuncheol Jung and Pascal Devant and Carter Ching and Mineto Ota and Emma Dann and Ronghui Zhu and Chandrima Modak and Ana Vasquez-Ibarra and Jennifer R. Hamilton and Zachary Steinhart and Wayne Ngo and Luis Sandoval and Jae Hyung Jung and Jae Hyun J. Lee and Da Xu and Meirui An and Esha Urs and Peixin Amy Chen and Vincent Allain and Takuya Tada and Luke A. Gilbert and Brian R. Shy and Jonathan K. Pritchard and James K. Nuñez and Nathaniel R. Landau and David R. Liu and Justin Eyquem and Jennifer A. Doudna and Alexander Marson and Julia Carnevale},
  year = {2026},
  journal = {Nature Biotechnology},
  doi = {10.1038/s41587-026-03258-2},
  url = {https://doi.org/10.1038/s41587-026-03258-2}
}

RIS

TY  - JOUR
TI  - Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells
AU  - Hyuncheol Jung
AU  - Pascal Devant
AU  - Carter Ching
AU  - Mineto Ota
AU  - Emma Dann
AU  - Ronghui Zhu
AU  - Chandrima Modak
AU  - Ana Vasquez-Ibarra
AU  - Jennifer R. Hamilton
AU  - Zachary Steinhart
AU  - Wayne Ngo
AU  - Luis Sandoval
AU  - Jae Hyung Jung
AU  - Jae Hyun J. Lee
AU  - Da Xu
AU  - Meirui An
AU  - Esha Urs
AU  - Peixin Amy Chen
AU  - Vincent Allain
AU  - Takuya Tada
AU  - Luke A. Gilbert
AU  - Brian R. Shy
AU  - Jonathan K. Pritchard
AU  - James K. Nuñez
AU  - Nathaniel R. Landau
AU  - David R. Liu
AU  - Justin Eyquem
AU  - Jennifer A. Doudna
AU  - Alexander Marson
AU  - Julia Carnevale
PY  - 2026
JO  - Nature Biotechnology
DO  - 10.1038/s41587-026-03258-2
UR  - https://doi.org/10.1038/s41587-026-03258-2
ER  -

APA

Jung, H., Devant, P., Ching, C., Ota, M., Dann, E., Zhu, R., Modak, C., Vasquez-Ibarra, A., Hamilton, J. R., Steinhart, Z., Ngo, W., Sandoval, L., Jung, J. H., Lee, J. H. J., Xu, D., An, M., Urs, E., Chen, P. A., Allain, V., Tada, T., Gilbert, L. A., Shy, B. R., Pritchard, J. K., Nuñez, J. K., Landau, N. R., Liu, D. R., Eyquem, J., Doudna, J. A., Marson, A., & Carnevale, J. (2026). Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells. Nature Biotechnology. https://doi.org/10.1038/s41587-026-03258-2

Source records

crossref · retrieved 2026-09-25T17:23:24.130Z