A pervasive RT–qPCR artifact inflates RNA knockdown by RNA-targeting CRISPR

Leslie Watkins, Alan Zhu, Bin Wu

Open source

DOI: 10.1038/s41587-026-03291-1
Published: 2026-09-01
Container: Nature Biotechnology
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41587-026-03291-1,
  title = {A pervasive RT–qPCR artifact inflates RNA knockdown by RNA-targeting CRISPR},
  author = {Leslie Watkins and Alan Zhu and Bin Wu},
  year = {2026},
  journal = {Nature Biotechnology},
  doi = {10.1038/s41587-026-03291-1},
  url = {https://doi.org/10.1038/s41587-026-03291-1}
}

RIS

TY  - JOUR
TI  - A pervasive RT–qPCR artifact inflates RNA knockdown by RNA-targeting CRISPR
AU  - Leslie Watkins
AU  - Alan Zhu
AU  - Bin Wu
PY  - 2026
JO  - Nature Biotechnology
DO  - 10.1038/s41587-026-03291-1
UR  - https://doi.org/10.1038/s41587-026-03291-1
ER  -

APA

Watkins, L., Zhu, A., & Wu, B. (2026). A pervasive RT–qPCR artifact inflates RNA knockdown by RNA-targeting CRISPR. Nature Biotechnology. https://doi.org/10.1038/s41587-026-03291-1

Source records

crossref · retrieved 2026-09-25T22:52:25.056Z