Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL, Fine RS, Guo X, Schurmann C, Lempradl A, Marouli E, Mahajan A, Winkler TW, Locke AE, Medina-Gomez C, Esko T, Vedantam S, Giri A, Lo KS, Alfred T, Mudgal P, Ng MCY, Heard-Costa NL, Feitosa MF, Manning AK, Willems SM, Sivapalaratnam S, Abecasis G, Alam DS, Allison M, Amouyel P, Arzumanyan Z, Balkau B, Bastarache L, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bottinger EP, Bowden DW, Brandslund I, Broer L, Burt AA, Butterworth AS, Caulfield MJ, Cesana G, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Collins FS, Cook JP, Cox AJ, Crosslin DS, Danesh J, de Bakker PIW, Denus S, Mutsert R, Dedoussis G, Demerath EW, Dennis JG, Denny JC, Di Angelantonio E, Dörr M, Drenos F, Dubé MP, Dunning AM, Easton DF, Elliott P, Evangelou E, Farmaki AE, Feng S, Ferrannini E, Ferrieres J, Florez JC, Fornage M, Fox CS, Franks PW, Friedrich N, Gan W, Gandin I, Gasparini P, Giedraitis V, Girotto G, Gorski M, Grallert H, Grarup N, Grove ML, Gustafsson S, Haessler J, Hansen T, Hattersley AT, Hayward C, Heid IM, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Hung YJ, Hveem K, Ikram MA, Ingelsson E, Jackson AU, Jarvik GP, Jia Y, Jørgensen T, Jousilahti P, Justesen JM, Kahali B, Karaleftheri M, Kardia SLR, Karpe F, Kee F, Kitajima H, Komulainen P, Kooner JS, Kovacs P, Krämer BK, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, Lange LA, Langenberg C, Larson EB, Lee NR, Lee WJ, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu CT, Liu DJ, Luan J, Lyytikäinen LP, MacGregor S, Mägi R, Männistö S, Marenne G, Marten J, Masca NGD, McCarthy MI, Meidtner K, Mihailov E, Moilanen L, Moitry M, Mook-Kanamori DO, Morgan A, Morris AP, Müller-Nurasyid M, Munroe PB, Narisu N, Nelson CP, Neville M, Ntalla I, O'Connell JR, Owen KR, Pedersen O, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JRB, Pers TH, Ewing A, Polasek O, Raitakari OT, Rasheed A, Raulerson CK, Rauramaa R, Reilly DF, Reiner AP, Ridker PM, Rivas MA, Robertson NR, Robino A, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe M, Sim X, Slater AJ, Small KS, Smith BH, Smith JA, Southam L, Spector TD, Speliotes EK, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swart KMA, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tönjes A, Torres M, Tsafantakis E, Tuomilehto J, Uitterlinden AG, Uusitupa M, van Duijn CM, Vanhala M, Varma R, Vermeulen SH, Vestergaard H, Vitart V, Vogt TF, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang F, Wang CA, Wang S, Wareham NJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Wood AR, Wu Y, Yaghootkar H, Yao J, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zheng H, Zhou W, Zillikens MC, Rivadeneira F, Borecki IB, Pospisilik JA, Deloukas P, Frayling TM, Lettre G, Mohlke KL, Rotter JI, Kutalik Z, Hirschhorn JN, Cupples LA, Loos RJF, North KE, Lindgren CM, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators

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DOI
10.1038/s41588-018-0334-2
Published
2019 Mar
Container
Nature genetics
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41588-018-0334-2,
  title = {Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.},
  author = {Justice AE and Karaderi T and Highland HM and Young KL and Graff M and Lu Y and Turcot V and Auer PL and Fine RS and Guo X and Schurmann C and Lempradl A and Marouli E and Mahajan A and Winkler TW and Locke AE and Medina-Gomez C and Esko T and Vedantam S and Giri A and Lo KS and Alfred T and Mudgal P and Ng MCY and Heard-Costa NL and Feitosa MF and Manning AK and Willems SM and Sivapalaratnam S and Abecasis G and Alam DS and Allison M and Amouyel P and Arzumanyan Z and Balkau B and Bastarache L and Bergmann S and Bielak LF and Blüher M and Boehnke M and Boeing H and Boerwinkle E and Böger CA and Bork-Jensen J and Bottinger EP and Bowden DW and Brandslund I and Broer L and Burt AA and Butterworth AS and Caulfield MJ and Cesana G and Chambers JC and Chasman DI and Chen YI and Chowdhury R and Christensen C and Chu AY and Collins FS and Cook JP and Cox AJ and Crosslin DS and Danesh J and de Bakker PIW and Denus S and Mutsert R and Dedoussis G and Demerath EW and Dennis JG and Denny JC and Di Angelantonio E and Dörr M and Drenos F and Dubé MP and Dunning AM and Easton DF and Elliott P and Evangelou E and Farmaki AE and Feng S and Ferrannini E and Ferrieres J and Florez JC and Fornage M and Fox CS and Franks PW and Friedrich N and Gan W and Gandin I and Gasparini P and Giedraitis V and Girotto G and Gorski M and Grallert H and Grarup N and Grove ML and Gustafsson S and Haessler J and Hansen T and Hattersley AT and Hayward C and Heid IM and Holmen OL and Hovingh GK and Howson JMM and Hu Y and Hung YJ and Hveem K and Ikram MA and Ingelsson E and Jackson AU and Jarvik GP and Jia Y and Jørgensen T and Jousilahti P and Justesen JM and Kahali B and Karaleftheri M and Kardia SLR and Karpe F and Kee F and Kitajima H and Komulainen P and Kooner JS and Kovacs P and Krämer BK and Kuulasmaa K and Kuusisto J and Laakso M and Lakka TA and Lamparter D and Lange LA and Langenberg C and Larson EB and Lee NR and Lee WJ and Lehtimäki T and Lewis CE and Li H and Li J and Li-Gao R and Lin LA and Lin X and Lind L and Lindström J and Linneberg A and Liu CT and Liu DJ and Luan J and Lyytikäinen LP and MacGregor S and Mägi R and Männistö S and Marenne G and Marten J and Masca NGD and McCarthy MI and Meidtner K and Mihailov E and Moilanen L and Moitry M and Mook-Kanamori DO and Morgan A and Morris AP and Müller-Nurasyid M and Munroe PB and Narisu N and Nelson CP and Neville M and Ntalla I and O'Connell JR and Owen KR and Pedersen O and Peloso GM and Pennell CE and Perola M and Perry JA and Perry JRB and Pers TH and Ewing A and Polasek O and Raitakari OT and Rasheed A and Raulerson CK and Rauramaa R and Reilly DF and Reiner AP and Ridker PM and Rivas MA and Robertson NR and Robino A and Rudan I and Ruth KS and Saleheen D and Salomaa V and Samani NJ and Schreiner PJ and Schulze MB and Scott RA and Segura-Lepe M and Sim X and Slater AJ and Small KS and Smith BH and Smith JA and Southam L and Spector TD and Speliotes EK and Stefansson K and Steinthorsdottir V and Stirrups KE and Strauch K and Stringham HM and Stumvoll M and Sun L and Surendran P and Swart KMA and Tardif JC and Taylor KD and Teumer A and Thompson DJ and Thorleifsson G and Thorsteinsdottir U and Thuesen BH and Tönjes A and Torres M and Tsafantakis E and Tuomilehto J and Uitterlinden AG and Uusitupa M and van Duijn CM and Vanhala M and Varma R and Vermeulen SH and Vestergaard H and Vitart V and Vogt TF and Vuckovic D and Wagenknecht LE and Walker M and Wallentin L and Wang F and Wang CA and Wang S and Wareham NJ and Warren HR and Waterworth DM and Wessel J and White HD and Willer CJ and Wilson JG and Wood AR and Wu Y and Yaghootkar H and Yao J and Yerges-Armstrong LM and Young R and Zeggini E and Zhan X and Zhang W and Zhao JH and Zhao W and Zheng H and Zhou W and Zillikens MC and Rivadeneira F and Borecki IB and Pospisilik JA and Deloukas P and Frayling TM and Lettre G and Mohlke KL and Rotter JI and Kutalik Z and Hirschhorn JN and Cupples LA and Loos RJF and North KE and Lindgren CM and CHD Exome+ Consortium and Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium and EPIC-CVD Consortium and ExomeBP Consortium and Global Lipids Genetic Consortium and GoT2D Genes Consortium and InterAct and ReproGen Consortium and T2D-Genes Consortium and MAGIC Investigators},
  year = {2019},
  journal = {Nature genetics},
  doi = {10.1038/s41588-018-0334-2},
  url = {https://doi.org/10.1038/s41588-018-0334-2}
}

RIS

TY  - JOUR
TI  - Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
AU  - Justice AE
AU  - Karaderi T
AU  - Highland HM
AU  - Young KL
AU  - Graff M
AU  - Lu Y
AU  - Turcot V
AU  - Auer PL
AU  - Fine RS
AU  - Guo X
AU  - Schurmann C
AU  - Lempradl A
AU  - Marouli E
AU  - Mahajan A
AU  - Winkler TW
AU  - Locke AE
AU  - Medina-Gomez C
AU  - Esko T
AU  - Vedantam S
AU  - Giri A
AU  - Lo KS
AU  - Alfred T
AU  - Mudgal P
AU  - Ng MCY
AU  - Heard-Costa NL
AU  - Feitosa MF
AU  - Manning AK
AU  - Willems SM
AU  - Sivapalaratnam S
AU  - Abecasis G
AU  - Alam DS
AU  - Allison M
AU  - Amouyel P
AU  - Arzumanyan Z
AU  - Balkau B
AU  - Bastarache L
AU  - Bergmann S
AU  - Bielak LF
AU  - Blüher M
AU  - Boehnke M
AU  - Boeing H
AU  - Boerwinkle E
AU  - Böger CA
AU  - Bork-Jensen J
AU  - Bottinger EP
AU  - Bowden DW
AU  - Brandslund I
AU  - Broer L
AU  - Burt AA
AU  - Butterworth AS
AU  - Caulfield MJ
AU  - Cesana G
AU  - Chambers JC
AU  - Chasman DI
AU  - Chen YI
AU  - Chowdhury R
AU  - Christensen C
AU  - Chu AY
AU  - Collins FS
AU  - Cook JP
AU  - Cox AJ
AU  - Crosslin DS
AU  - Danesh J
AU  - de Bakker PIW
AU  - Denus S
AU  - Mutsert R
AU  - Dedoussis G
AU  - Demerath EW
AU  - Dennis JG
AU  - Denny JC
AU  - Di Angelantonio E
AU  - Dörr M
AU  - Drenos F
AU  - Dubé MP
AU  - Dunning AM
AU  - Easton DF
AU  - Elliott P
AU  - Evangelou E
AU  - Farmaki AE
AU  - Feng S
AU  - Ferrannini E
AU  - Ferrieres J
AU  - Florez JC
AU  - Fornage M
AU  - Fox CS
AU  - Franks PW
AU  - Friedrich N
AU  - Gan W
AU  - Gandin I
AU  - Gasparini P
AU  - Giedraitis V
AU  - Girotto G
AU  - Gorski M
AU  - Grallert H
AU  - Grarup N
AU  - Grove ML
AU  - Gustafsson S
AU  - Haessler J
AU  - Hansen T
AU  - Hattersley AT
AU  - Hayward C
AU  - Heid IM
AU  - Holmen OL
AU  - Hovingh GK
AU  - Howson JMM
AU  - Hu Y
AU  - Hung YJ
AU  - Hveem K
AU  - Ikram MA
AU  - Ingelsson E
AU  - Jackson AU
AU  - Jarvik GP
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AU  - Jørgensen T
AU  - Jousilahti P
AU  - Justesen JM
AU  - Kahali B
AU  - Karaleftheri M
AU  - Kardia SLR
AU  - Karpe F
AU  - Kee F
AU  - Kitajima H
AU  - Komulainen P
AU  - Kooner JS
AU  - Kovacs P
AU  - Krämer BK
AU  - Kuulasmaa K
AU  - Kuusisto J
AU  - Laakso M
AU  - Lakka TA
AU  - Lamparter D
AU  - Lange LA
AU  - Langenberg C
AU  - Larson EB
AU  - Lee NR
AU  - Lee WJ
AU  - Lehtimäki T
AU  - Lewis CE
AU  - Li H
AU  - Li J
AU  - Li-Gao R
AU  - Lin LA
AU  - Lin X
AU  - Lind L
AU  - Lindström J
AU  - Linneberg A
AU  - Liu CT
AU  - Liu DJ
AU  - Luan J
AU  - Lyytikäinen LP
AU  - MacGregor S
AU  - Mägi R
AU  - Männistö S
AU  - Marenne G
AU  - Marten J
AU  - Masca NGD
AU  - McCarthy MI
AU  - Meidtner K
AU  - Mihailov E
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AU  - Moitry M
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AU  - Morgan A
AU  - Morris AP
AU  - Müller-Nurasyid M
AU  - Munroe PB
AU  - Narisu N
AU  - Nelson CP
AU  - Neville M
AU  - Ntalla I
AU  - O'Connell JR
AU  - Owen KR
AU  - Pedersen O
AU  - Peloso GM
AU  - Pennell CE
AU  - Perola M
AU  - Perry JA
AU  - Perry JRB
AU  - Pers TH
AU  - Ewing A
AU  - Polasek O
AU  - Raitakari OT
AU  - Rasheed A
AU  - Raulerson CK
AU  - Rauramaa R
AU  - Reilly DF
AU  - Reiner AP
AU  - Ridker PM
AU  - Rivas MA
AU  - Robertson NR
AU  - Robino A
AU  - Rudan I
AU  - Ruth KS
AU  - Saleheen D
AU  - Salomaa V
AU  - Samani NJ
AU  - Schreiner PJ
AU  - Schulze MB
AU  - Scott RA
AU  - Segura-Lepe M
AU  - Sim X
AU  - Slater AJ
AU  - Small KS
AU  - Smith BH
AU  - Smith JA
AU  - Southam L
AU  - Spector TD
AU  - Speliotes EK
AU  - Stefansson K
AU  - Steinthorsdottir V
AU  - Stirrups KE
AU  - Strauch K
AU  - Stringham HM
AU  - Stumvoll M
AU  - Sun L
AU  - Surendran P
AU  - Swart KMA
AU  - Tardif JC
AU  - Taylor KD
AU  - Teumer A
AU  - Thompson DJ
AU  - Thorleifsson G
AU  - Thorsteinsdottir U
AU  - Thuesen BH
AU  - Tönjes A
AU  - Torres M
AU  - Tsafantakis E
AU  - Tuomilehto J
AU  - Uitterlinden AG
AU  - Uusitupa M
AU  - van Duijn CM
AU  - Vanhala M
AU  - Varma R
AU  - Vermeulen SH
AU  - Vestergaard H
AU  - Vitart V
AU  - Vogt TF
AU  - Vuckovic D
AU  - Wagenknecht LE
AU  - Walker M
AU  - Wallentin L
AU  - Wang F
AU  - Wang CA
AU  - Wang S
AU  - Wareham NJ
AU  - Warren HR
AU  - Waterworth DM
AU  - Wessel J
AU  - White HD
AU  - Willer CJ
AU  - Wilson JG
AU  - Wood AR
AU  - Wu Y
AU  - Yaghootkar H
AU  - Yao J
AU  - Yerges-Armstrong LM
AU  - Young R
AU  - Zeggini E
AU  - Zhan X
AU  - Zhang W
AU  - Zhao JH
AU  - Zhao W
AU  - Zheng H
AU  - Zhou W
AU  - Zillikens MC
AU  - Rivadeneira F
AU  - Borecki IB
AU  - Pospisilik JA
AU  - Deloukas P
AU  - Frayling TM
AU  - Lettre G
AU  - Mohlke KL
AU  - Rotter JI
AU  - Kutalik Z
AU  - Hirschhorn JN
AU  - Cupples LA
AU  - Loos RJF
AU  - North KE
AU  - Lindgren CM
AU  - CHD Exome+ Consortium
AU  - Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
AU  - EPIC-CVD Consortium
AU  - ExomeBP Consortium
AU  - Global Lipids Genetic Consortium
AU  - GoT2D Genes Consortium
AU  - InterAct
AU  - ReproGen Consortium
AU  - T2D-Genes Consortium
AU  - MAGIC Investigators
PY  - 2019
JO  - Nature genetics
DO  - 10.1038/s41588-018-0334-2
UR  - https://doi.org/10.1038/s41588-018-0334-2
ER  -

APA

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