Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.

van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker AM, Gawor K, Westeneng HJ, Tazelaar GHP, van Eijk KR, Kooyman M, Byrne RP, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith BN, Gromicho M, Chandran S, Pal S, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Sendtner M, Meyer T, Başak N, van der Kooi AJ, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D'Alfonso S, Sorarù G, Siciliano G, Filosto M, Padovani A, Chiò A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh RH, Bell S, Vourc'h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina JS, Assialioui A, Rojas-García R, Dion PA, Ross JP, Ludolph AC, Weishaupt JH, Brenner D, Freischmidt A, Bensimon G, Brice A, Durr A, Payan CAM, Saker-Delye S, Wood NW, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman DC, Olsen CM, Uitterlinden AG, Hofman A, Rietschel M, Cichon S, Nöthen MM, Amouyel P, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Traynor BJ, Singleton AB, Mitne Neto M, Cauchi RJ, Ophoff RA, Wiedau-Pazos M, Lomen-Hoerth C, van Deerlin VM, Grosskreutz J, Roediger A, Gaur N, Jörk A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte OW, Steinbach R, Hübner CA, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glavač M, Glavač D, Stević Z, Drory V, Povedano M, Blair IP, Kiernan MC, Benyamin B, Henderson RD, Furlong S, Mathers S, McCombe PA, Needham M, Ngo ST, Nicholson GA, Pamphlett R, Rowe DB, Steyn FJ, Williams KL, Mather KA, Sachdev PS, Henders AK, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau GA, Silani V, Curtis CJ, Breen G, Glass JD, Brown RH, Landers JE, Shaw CE, Andersen PM, Groen EJN, van Es MA, Pasterkamp RJ, Fan D, Garton FC, McRae AF, Davey Smith G, Gaunt TR, Eberle MA, Mill J, McLaughlin RL, Hardiman O, Kenna KP, Wray NR, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg LH, Veldink JH.

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DOI: 10.1038/s41588-021-00973-1
Published: 2021-12-06
Container: Nat Genet
Publisher: Not recorded
Open access: yes

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BibTeX

@article{allodium:10.1038/s41588-021-00973-1,
  title = {Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.},
  author = {van Rheenen W and  van der Spek RAA and  Bakker MK and  van Vugt JJFA and  Hop PJ and  Zwamborn RAJ and  de Klein N and  Westra HJ and  Bakker OB and  Deelen P and  Shireby G and  Hannon E and  Moisse M and  Baird D and  Restuadi R and  Dolzhenko E and  Dekker AM and  Gawor K and  Westeneng HJ and  Tazelaar GHP and  van Eijk KR and  Kooyman M and  Byrne RP and  Doherty M and  Heverin M and  Al Khleifat A and  Iacoangeli A and  Shatunov A and  Ticozzi N and  Cooper-Knock J and  Smith BN and  Gromicho M and  Chandran S and  Pal S and  Morrison KE and  Shaw PJ and  Hardy J and  Orrell RW and  Sendtner M and  Meyer T and  Başak N and  van der Kooi AJ and  Ratti A and  Fogh I and  Gellera C and  Lauria G and  Corti S and  Cereda C and  Sproviero D and  D'Alfonso S and  Sorarù G and  Siciliano G and  Filosto M and  Padovani A and  Chiò A and  Calvo A and  Moglia C and  Brunetti M and  Canosa A and  Grassano M and  Beghi E and  Pupillo E and  Logroscino G and  Nefussy B and  Osmanovic A and  Nordin A and  Lerner Y and  Zabari M and  Gotkine M and  Baloh RH and  Bell S and  Vourc'h P and  Corcia P and  Couratier P and  Millecamps S and  Meininger V and  Salachas F and  Mora Pardina JS and  Assialioui A and  Rojas-García R and  Dion PA and  Ross JP and  Ludolph AC and  Weishaupt JH and  Brenner D and  Freischmidt A and  Bensimon G and  Brice A and  Durr A and  Payan CAM and  Saker-Delye S and  Wood NW and  Topp S and  Rademakers R and  Tittmann L and  Lieb W and  Franke A and  Ripke S and  Braun A and  Kraft J and  Whiteman DC and  Olsen CM and  Uitterlinden AG and  Hofman A and  Rietschel M and  Cichon S and  Nöthen MM and  Amouyel P and  SLALOM Consortium and  PARALS Consortium and  SLAGEN Consortium and  SLAP Consortium and  Traynor BJ and  Singleton AB and  Mitne Neto M and  Cauchi RJ and  Ophoff RA and  Wiedau-Pazos M and  Lomen-Hoerth C and  van Deerlin VM and  Grosskreutz J and  Roediger A and  Gaur N and  Jörk A and  Barthel T and  Theele E and  Ilse B and  Stubendorff B and  Witte OW and  Steinbach R and  Hübner CA and  Graff C and  Brylev L and  Fominykh V and  Demeshonok V and  Ataulina A and  Rogelj B and  Koritnik B and  Zidar J and  Ravnik-Glavač M and  Glavač D and  Stević Z and  Drory V and  Povedano M and  Blair IP and  Kiernan MC and  Benyamin B and  Henderson RD and  Furlong S and  Mathers S and  McCombe PA and  Needham M and  Ngo ST and  Nicholson GA and  Pamphlett R and  Rowe DB and  Steyn FJ and  Williams KL and  Mather KA and  Sachdev PS and  Henders AK and  Wallace L and  de Carvalho M and  Pinto S and  Petri S and  Weber M and  Rouleau GA and  Silani V and  Curtis CJ and  Breen G and  Glass JD and  Brown RH and  Landers JE and  Shaw CE and  Andersen PM and  Groen EJN and  van Es MA and  Pasterkamp RJ and  Fan D and  Garton FC and  McRae AF and  Davey Smith G and  Gaunt TR and  Eberle MA and  Mill J and  McLaughlin RL and  Hardiman O and  Kenna KP and  Wray NR and  Tsai E and  Runz H and  Franke L and  Al-Chalabi A and  Van Damme P and  van den Berg LH and  Veldink JH.},
  year = {2021},
  journal = {Nat Genet},
  doi = {10.1038/s41588-021-00973-1},
  url = {https://doi.org/10.1038/s41588-021-00973-1}
}

RIS

TY  - JOUR
TI  - Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
AU  - van Rheenen W
AU  -  van der Spek RAA
AU  -  Bakker MK
AU  -  van Vugt JJFA
AU  -  Hop PJ
AU  -  Zwamborn RAJ
AU  -  de Klein N
AU  -  Westra HJ
AU  -  Bakker OB
AU  -  Deelen P
AU  -  Shireby G
AU  -  Hannon E
AU  -  Moisse M
AU  -  Baird D
AU  -  Restuadi R
AU  -  Dolzhenko E
AU  -  Dekker AM
AU  -  Gawor K
AU  -  Westeneng HJ
AU  -  Tazelaar GHP
AU  -  van Eijk KR
AU  -  Kooyman M
AU  -  Byrne RP
AU  -  Doherty M
AU  -  Heverin M
AU  -  Al Khleifat A
AU  -  Iacoangeli A
AU  -  Shatunov A
AU  -  Ticozzi N
AU  -  Cooper-Knock J
AU  -  Smith BN
AU  -  Gromicho M
AU  -  Chandran S
AU  -  Pal S
AU  -  Morrison KE
AU  -  Shaw PJ
AU  -  Hardy J
AU  -  Orrell RW
AU  -  Sendtner M
AU  -  Meyer T
AU  -  Başak N
AU  -  van der Kooi AJ
AU  -  Ratti A
AU  -  Fogh I
AU  -  Gellera C
AU  -  Lauria G
AU  -  Corti S
AU  -  Cereda C
AU  -  Sproviero D
AU  -  D'Alfonso S
AU  -  Sorarù G
AU  -  Siciliano G
AU  -  Filosto M
AU  -  Padovani A
AU  -  Chiò A
AU  -  Calvo A
AU  -  Moglia C
AU  -  Brunetti M
AU  -  Canosa A
AU  -  Grassano M
AU  -  Beghi E
AU  -  Pupillo E
AU  -  Logroscino G
AU  -  Nefussy B
AU  -  Osmanovic A
AU  -  Nordin A
AU  -  Lerner Y
AU  -  Zabari M
AU  -  Gotkine M
AU  -  Baloh RH
AU  -  Bell S
AU  -  Vourc'h P
AU  -  Corcia P
AU  -  Couratier P
AU  -  Millecamps S
AU  -  Meininger V
AU  -  Salachas F
AU  -  Mora Pardina JS
AU  -  Assialioui A
AU  -  Rojas-García R
AU  -  Dion PA
AU  -  Ross JP
AU  -  Ludolph AC
AU  -  Weishaupt JH
AU  -  Brenner D
AU  -  Freischmidt A
AU  -  Bensimon G
AU  -  Brice A
AU  -  Durr A
AU  -  Payan CAM
AU  -  Saker-Delye S
AU  -  Wood NW
AU  -  Topp S
AU  -  Rademakers R
AU  -  Tittmann L
AU  -  Lieb W
AU  -  Franke A
AU  -  Ripke S
AU  -  Braun A
AU  -  Kraft J
AU  -  Whiteman DC
AU  -  Olsen CM
AU  -  Uitterlinden AG
AU  -  Hofman A
AU  -  Rietschel M
AU  -  Cichon S
AU  -  Nöthen MM
AU  -  Amouyel P
AU  -  SLALOM Consortium
AU  -  PARALS Consortium
AU  -  SLAGEN Consortium
AU  -  SLAP Consortium
AU  -  Traynor BJ
AU  -  Singleton AB
AU  -  Mitne Neto M
AU  -  Cauchi RJ
AU  -  Ophoff RA
AU  -  Wiedau-Pazos M
AU  -  Lomen-Hoerth C
AU  -  van Deerlin VM
AU  -  Grosskreutz J
AU  -  Roediger A
AU  -  Gaur N
AU  -  Jörk A
AU  -  Barthel T
AU  -  Theele E
AU  -  Ilse B
AU  -  Stubendorff B
AU  -  Witte OW
AU  -  Steinbach R
AU  -  Hübner CA
AU  -  Graff C
AU  -  Brylev L
AU  -  Fominykh V
AU  -  Demeshonok V
AU  -  Ataulina A
AU  -  Rogelj B
AU  -  Koritnik B
AU  -  Zidar J
AU  -  Ravnik-Glavač M
AU  -  Glavač D
AU  -  Stević Z
AU  -  Drory V
AU  -  Povedano M
AU  -  Blair IP
AU  -  Kiernan MC
AU  -  Benyamin B
AU  -  Henderson RD
AU  -  Furlong S
AU  -  Mathers S
AU  -  McCombe PA
AU  -  Needham M
AU  -  Ngo ST
AU  -  Nicholson GA
AU  -  Pamphlett R
AU  -  Rowe DB
AU  -  Steyn FJ
AU  -  Williams KL
AU  -  Mather KA
AU  -  Sachdev PS
AU  -  Henders AK
AU  -  Wallace L
AU  -  de Carvalho M
AU  -  Pinto S
AU  -  Petri S
AU  -  Weber M
AU  -  Rouleau GA
AU  -  Silani V
AU  -  Curtis CJ
AU  -  Breen G
AU  -  Glass JD
AU  -  Brown RH
AU  -  Landers JE
AU  -  Shaw CE
AU  -  Andersen PM
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AU  -  van Es MA
AU  -  Pasterkamp RJ
AU  -  Fan D
AU  -  Garton FC
AU  -  McRae AF
AU  -  Davey Smith G
AU  -  Gaunt TR
AU  -  Eberle MA
AU  -  Mill J
AU  -  McLaughlin RL
AU  -  Hardiman O
AU  -  Kenna KP
AU  -  Wray NR
AU  -  Tsai E
AU  -  Runz H
AU  -  Franke L
AU  -  Al-Chalabi A
AU  -  Van Damme P
AU  -  van den Berg LH
AU  -  Veldink JH.
PY  - 2021
JO  - Nat Genet
DO  - 10.1038/s41588-021-00973-1
UR  - https://doi.org/10.1038/s41588-021-00973-1
ER  -

APA

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