The impact of common and rare genetic variants on bradyarrhythmia development

Lu-Chen Weng, Joel T. Rämö, Sean J. Jurgens, Shaan Khurshid, Mark Chaffin, Amelia Weber Hall, Valerie N. Morrill, Xin Wang, Victor Nauffal, Yan V. Sun, Dominik Beer, Simon Lee, Girish N. Nadkarni, ThuyVy Duong, Biqi Wang, Tomasz Czuba, Thomas R. Austin, Zachary T. Yoneda, Daniel J. Friedman, Anne Clayton, Matthew C. Hyman, Renae L. Judy, Allan C. Skanes, Kate M. Orland, Timothy M. Treu, Matthew T. Oetjens, Alvaro Alonso, Elsayed Z. Soliman, Honghuang Lin, Kathryn L. Lunetta, Jesper van der Pals, Tariq Z. Issa, Navid A. Nafissi, Heidi T. May, Peter Leong-Sit, Carolina Roselli, Seung Hoan Choi, Unknown, Unknown, Unknown, Goncalo Abecasis, Aris Baras, Michael Cantor, Giovanni Coppola, Aris Economides, Luca A. Lotta, John D. Overton, Jeffrey G. Reid, Alan Shuldiner, Christina Beechert, Caitlin Forsythe, Erin D. Fuller, Zhenhua Gu, Michael Lattari, Alexander Lopez, Thomas D. Schleicher, Maria Sotiropoulos Padilla, Louis Widom, Sarah E. Wolf, Manasi Pradhan, Kia Manoochehri, Ricardo H. Ulloa, Xiaodong Bai, Suganthi Balasubramanian, Andrew Blumenfeld, Boris Boutkov, Gisu Eom, Lukas Habegger, Alicia Hawes, Shareef Khalid, Olga Krasheninina, Rouel Lanche, Adam J. Mansfield, Evan K. Maxwell, Mrunali Nafde, Sean O’Keeffe, Max Orelus, Razvan Panea, Tommy Polanco, Ayesha Rasool, William Salerno, Jeffrey C. Staples, Marcus B. Jones, Lyndon J. Mitnaul, Habib R. Khan, Stacey Knight, Richard Karlsson Linnér, Connie R. Bezzina, Samuli Ripatti, Susan R. Heckbert, J. Michael Gaziano, Ruth J. F. Loos, Bruce M. Psaty, J. Gustav Smith, Emelia J. Benjamin, Dan E. Arking, Daniel J. Rader, Svati H. Shah, Dan M. Roden, Scott M. Damrauer, Lee L. Eckhardt, Jason D. Roberts, Michael J. Cutler, M. Benjamin Shoemaker, Christopher M. Haggerty, Kelly Cho, Aarno Palotie, Peter W. F. Wilson, Patrick T. Ellinor, Steven A. Lubitz

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DOI: 10.1038/s41588-024-01978-2
Published: 2025-01
Container: Nature Genetics
Publisher: Springer Science and Business Media LLC
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Cite this work

BibTeX

@article{allodium:10.1038/s41588-024-01978-2,
title = {The impact of common and rare genetic variants on bradyarrhythmia development},
author = {Lu-Chen Weng and Joel T. Rämö and Sean J. Jurgens and Shaan Khurshid and Mark Chaffin and Amelia Weber Hall and Valerie N. Morrill and Xin Wang and Victor Nauffal and Yan V. Sun and Dominik Beer and Simon Lee and Girish N. Nadkarni and ThuyVy Duong and Biqi Wang and Tomasz Czuba and Thomas R. Austin and Zachary T. Yoneda and Daniel J. Friedman and Anne Clayton and Matthew C. Hyman and Renae L. Judy and Allan C. Skanes and Kate M. Orland and Timothy M. Treu and Matthew T. Oetjens and Alvaro Alonso and Elsayed Z. Soliman and Honghuang Lin and Kathryn L. Lunetta and Jesper van der Pals and Tariq Z. Issa and Navid A. Nafissi and Heidi T. May and Peter Leong-Sit and Carolina Roselli and Seung Hoan Choi and Unknown and Unknown and Unknown and Goncalo Abecasis and Aris Baras and Michael Cantor and Giovanni Coppola and Aris Economides and Luca A. Lotta and John D. Overton and Jeffrey G. Reid and Alan Shuldiner and Christina Beechert and Caitlin Forsythe and Erin D. Fuller and Zhenhua Gu and Michael Lattari and Alexander Lopez and Thomas D. Schleicher and Maria Sotiropoulos Padilla and Louis Widom and Sarah E. Wolf and Manasi Pradhan and Kia Manoochehri and Ricardo H. Ulloa and Xiaodong Bai and Suganthi Balasubramanian and Andrew Blumenfeld and Boris Boutkov and Gisu Eom and Lukas Habegger and Alicia Hawes and Shareef Khalid and Olga Krasheninina and Rouel Lanche and Adam J. Mansfield and Evan K. Maxwell and Mrunali Nafde and Sean O’Keeffe and Max Orelus and Razvan Panea and Tommy Polanco and Ayesha Rasool and William Salerno and Jeffrey C. Staples and Marcus B. Jones and Lyndon J. Mitnaul and Habib R. Khan and Stacey Knight and Richard Karlsson Linnér and Connie R. Bezzina and Samuli Ripatti and Susan R. Heckbert and J. Michael Gaziano and Ruth J. F. Loos and Bruce M. Psaty and J. Gustav Smith and Emelia J. Benjamin and Dan E. Arking and Daniel J. Rader and Svati H. Shah and Dan M. Roden and Scott M. Damrauer and Lee L. Eckhardt and Jason D. Roberts and Michael J. Cutler and M. Benjamin Shoemaker and Christopher M. Haggerty and Kelly Cho and Aarno Palotie and Peter W. F. Wilson and Patrick T. Ellinor and Steven A. Lubitz},
year = {2025},
journal = {Nature Genetics},
doi = {10.1038/s41588-024-01978-2},
url = {https://doi.org/10.1038/s41588-024-01978-2}
}

RIS

TY  - JOUR
TI  - The impact of common and rare genetic variants on bradyarrhythmia development
AU  - Lu-Chen Weng
AU  - Joel T. Rämö
AU  - Sean J. Jurgens
AU  - Shaan Khurshid
AU  - Mark Chaffin
AU  - Amelia Weber Hall
AU  - Valerie N. Morrill
AU  - Xin Wang
AU  - Victor Nauffal
AU  - Yan V. Sun
AU  - Dominik Beer
AU  - Simon Lee
AU  - Girish N. Nadkarni
AU  - ThuyVy Duong
AU  - Biqi Wang
AU  - Tomasz Czuba
AU  - Thomas R. Austin
AU  - Zachary T. Yoneda
AU  - Daniel J. Friedman
AU  - Anne Clayton
AU  - Matthew C. Hyman
AU  - Renae L. Judy
AU  - Allan C. Skanes
AU  - Kate M. Orland
AU  - Timothy M. Treu
AU  - Matthew T. Oetjens
AU  - Alvaro Alonso
AU  - Elsayed Z. Soliman
AU  - Honghuang Lin
AU  - Kathryn L. Lunetta
AU  - Jesper van der Pals
AU  - Tariq Z. Issa
AU  - Navid A. Nafissi
AU  - Heidi T. May
AU  - Peter Leong-Sit
AU  - Carolina Roselli
AU  - Seung Hoan Choi
AU  - Unknown
AU  - Unknown
AU  - Unknown
AU  - Goncalo Abecasis
AU  - Aris Baras
AU  - Michael Cantor
AU  - Giovanni Coppola
AU  - Aris Economides
AU  - Luca A. Lotta
AU  - John D. Overton
AU  - Jeffrey G. Reid
AU  - Alan Shuldiner
AU  - Christina Beechert
AU  - Caitlin Forsythe
AU  - Erin D. Fuller
AU  - Zhenhua Gu
AU  - Michael Lattari
AU  - Alexander Lopez
AU  - Thomas D. Schleicher
AU  - Maria Sotiropoulos Padilla
AU  - Louis Widom
AU  - Sarah E. Wolf
AU  - Manasi Pradhan
AU  - Kia Manoochehri
AU  - Ricardo H. Ulloa
AU  - Xiaodong Bai
AU  - Suganthi Balasubramanian
AU  - Andrew Blumenfeld
AU  - Boris Boutkov
AU  - Gisu Eom
AU  - Lukas Habegger
AU  - Alicia Hawes
AU  - Shareef Khalid
AU  - Olga Krasheninina
AU  - Rouel Lanche
AU  - Adam J. Mansfield
AU  - Evan K. Maxwell
AU  - Mrunali Nafde
AU  - Sean O’Keeffe
AU  - Max Orelus
AU  - Razvan Panea
AU  - Tommy Polanco
AU  - Ayesha Rasool
AU  - William Salerno
AU  - Jeffrey C. Staples
AU  - Marcus B. Jones
AU  - Lyndon J. Mitnaul
AU  - Habib R. Khan
AU  - Stacey Knight
AU  - Richard Karlsson Linnér
AU  - Connie R. Bezzina
AU  - Samuli Ripatti
AU  - Susan R. Heckbert
AU  - J. Michael Gaziano
AU  - Ruth J. F. Loos
AU  - Bruce M. Psaty
AU  - J. Gustav Smith
AU  - Emelia J. Benjamin
AU  - Dan E. Arking
AU  - Daniel J. Rader
AU  - Svati H. Shah
AU  - Dan M. Roden
AU  - Scott M. Damrauer
AU  - Lee L. Eckhardt
AU  - Jason D. Roberts
AU  - Michael J. Cutler
AU  - M. Benjamin Shoemaker
AU  - Christopher M. Haggerty
AU  - Kelly Cho
AU  - Aarno Palotie
AU  - Peter W. F. Wilson
AU  - Patrick T. Ellinor
AU  - Steven A. Lubitz
PY  - 2025
JO  - Nature Genetics
DO  - 10.1038/s41588-024-01978-2
UR  - https://doi.org/10.1038/s41588-024-01978-2
ER  -

APA

Weng, L., Rämö, J. T., Jurgens, S. J., Khurshid, S., Chaffin, M., Hall, A. W., Morrill, V. N., Wang, X., Nauffal, V., Sun, Y. V., Beer, D., Lee, S., Nadkarni, G. N., Duong, T., Wang, B., Czuba, T., Austin, T. R., Yoneda, Z. T., Friedman, D. J., Clayton, A., Hyman, M. C., Judy, R. L., Skanes, A. C., Orland, K. M., Treu, T. M., Oetjens, M. T., Alonso, A., Soliman, E. Z., Lin, H., Lunetta, K. L., Pals, J. V. D., Issa, T. Z., Nafissi, N. A., May, H. T., Leong-Sit, P., Roselli, C., Choi, S. H., Unknown, Unknown, Unknown, Abecasis, G., Baras, A., Cantor, M., Coppola, G., Economides, A., Lotta, L. A., Overton, J. D., Reid, J. G., Shuldiner, A., Beechert, C., Forsythe, C., Fuller, E. D., Gu, Z., Lattari, M., Lopez, A., Schleicher, T. D., Padilla, M. S., Widom, L., Wolf, S. E., Pradhan, M., Manoochehri, K., Ulloa, R. H., Bai, X., Balasubramanian, S., Blumenfeld, A., Boutkov, B., Eom, G., Habegger, L., Hawes, A., Khalid, S., Krasheninina, O., Lanche, R., Mansfield, A. J., Maxwell, E. K., Nafde, M., O’Keeffe, S., Orelus, M., Panea, R., Polanco, T., Rasool, A., Salerno, W., Staples, J. C., Jones, M. B., Mitnaul, L. J., Khan, H. R., Knight, S., Linnér, R. K., Bezzina, C. R., Ripatti, S., Heckbert, S. R., Gaziano, J. M., Loos, R. J. F., Psaty, B. M., Smith, J. G., Benjamin, E. J., Arking, D. E., Rader, D. J., Shah, S. H., Roden, D. M., Damrauer, S. M., Eckhardt, L. L., Roberts, J. D., Cutler, M. J., Shoemaker, M. B., Haggerty, C. M., Cho, K., Palotie, A., Wilson, P. W. F., Ellinor, P. T., & Lubitz, S. A. (2025). The impact of common and rare genetic variants on bradyarrhythmia development. Nature Genetics. https://doi.org/10.1038/s41588-024-01978-2

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