p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism.

Laue K, Pozzi S, Zerbib J, Bertolio R, Eliezer Y, Cohen-Sharir Y, Winkler T, Caputo M, Ricci AA, Adler L, Khoury R, Longobardi G, Slutsky R, Leikin-Frenkel AI, Ovadia S, Lange K, Rustighi A, Piazza S, Sacconi A, Magesh RY, Keller FN, Berthelet J, Schäffer A, Saad R, Israeli Dangoor S, Szczepanowska K, Barshack I, Liao Y, Malitsky S, Brandis A, Broggini T, Czabanka M, Shi W, Merino D, Watson EV, Blandino G, Erez A, Ashery-Padan R, Medyouf H, Bertero L, Del Sal G, Satchi-Fainaro R, Ben-David U

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DOI: 10.1038/s41588-025-02446-1
Published: 2026 Jan
Container: Nature genetics
Publisher: Not recorded
Open access: no

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Cite this work

BibTeX

@article{allodium:10.1038/s41588-025-02446-1,
  title = {p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism.},
  author = {Laue K and Pozzi S and Zerbib J and Bertolio R and Eliezer Y and Cohen-Sharir Y and Winkler T and Caputo M and Ricci AA and Adler L and Khoury R and Longobardi G and Slutsky R and Leikin-Frenkel AI and Ovadia S and Lange K and Rustighi A and Piazza S and Sacconi A and Magesh RY and Keller FN and Berthelet J and Schäffer A and Saad R and Israeli Dangoor S and Szczepanowska K and Barshack I and Liao Y and Malitsky S and Brandis A and Broggini T and Czabanka M and Shi W and Merino D and Watson EV and Blandino G and Erez A and Ashery-Padan R and Medyouf H and Bertero L and Del Sal G and Satchi-Fainaro R and Ben-David U},
  year = {2026},
  journal = {Nature genetics},
  doi = {10.1038/s41588-025-02446-1},
  url = {https://doi.org/10.1038/s41588-025-02446-1}
}

RIS

TY  - JOUR
TI  - p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism.
AU  - Laue K
AU  - Pozzi S
AU  - Zerbib J
AU  - Bertolio R
AU  - Eliezer Y
AU  - Cohen-Sharir Y
AU  - Winkler T
AU  - Caputo M
AU  - Ricci AA
AU  - Adler L
AU  - Khoury R
AU  - Longobardi G
AU  - Slutsky R
AU  - Leikin-Frenkel AI
AU  - Ovadia S
AU  - Lange K
AU  - Rustighi A
AU  - Piazza S
AU  - Sacconi A
AU  - Magesh RY
AU  - Keller FN
AU  - Berthelet J
AU  - Schäffer A
AU  - Saad R
AU  - Israeli Dangoor S
AU  - Szczepanowska K
AU  - Barshack I
AU  - Liao Y
AU  - Malitsky S
AU  - Brandis A
AU  - Broggini T
AU  - Czabanka M
AU  - Shi W
AU  - Merino D
AU  - Watson EV
AU  - Blandino G
AU  - Erez A
AU  - Ashery-Padan R
AU  - Medyouf H
AU  - Bertero L
AU  - Del Sal G
AU  - Satchi-Fainaro R
AU  - Ben-David U
PY  - 2026
JO  - Nature genetics
DO  - 10.1038/s41588-025-02446-1
UR  - https://doi.org/10.1038/s41588-025-02446-1
ER  -

APA

K, L., S, P., J, Z., R, B., Y, E., Y, C., T, W., M, C., AA, R., L, A., R, K., G, L., R, S., AI, L., S, O., K, L., A, R., S, P., A, S., RY, M., FN, K., J, B., A, S., R, S., S, I. D., K, S., I, B., Y, L., S, M., A, B., T, B., M, C., W, S., D, M., EV, W., G, B., A, E., R, A., H, M., L, B., G, D. S., R, S., & U, B. (2026). p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism.. Nature genetics. https://doi.org/10.1038/s41588-025-02446-1

Source records

pubmed · retrieved 2026-09-26T15:15:40.850Z
europe-pmc · retrieved 2026-09-26T15:15:40.850Z