A progeria syndrome links DNA hypermethylation to age-related pathology

Dan Sarni, Gráinne Neary, Paula L. Carroll, Chris S. Vink, Caroline V. Billard, Tomoya Isobe, Xiong Weng, Jordan R. Portman, Daniel L. McCartney, Patricia Heyn, Rob J. van ‘t Hof, Linda R. Morrison, Carol-Anne Martin, Colin Stok, Margaret E. Harley, Andrea Leitch, Maarten van den Ancker, Nic Robertson, Laura Kitto, Richard Clark, Michael Rennie, Anna Popravko, Jessica J. McClure, David A. Parry, Giuseppina Camiolo, Tom Leah, Hélène Jakobczyk, Roly Megaw, Lisa McKie, Grant F. Marshall, Nika Balkic, Jeanne Amiel, Tania Barragán Arévalo, Grace Bronken McCarthy, Catherine A. Buchanan, Alexandre Buffet, Alberto Cascón, Benjamin Cogne, Solene Conrad, Anna Maria Cueto-González, Maria Currás-Freixes, Gunnar Douzgos Houge, Chin-To Fong, Jaya K. George-Abraham, Kate Gibson, Lourdes Ibáñez, Nicola Longo, Charlotte Lussey-Lepoutre, Bradley S. Miller, Alejandro Moles-Fernandez, Nishitha R. Pillai, Tatiana Tvrdik, Marie Vincent, Emiy Yokoyama, Catherine M. Abbott, Francisco Jose Sanchez-Luque, Katrin Ottersbach, Cosimo De Bari, Anke J. Roelofs, Rebekah Tillotson, Kamil R. Kranc, Sara J. Brown, Riccardo E. Marioni, Mihaela Crisan, Berthold Göttgens, Neil C. Henderson, Robert K. Semple, Kevin B. Myant, Elaine Dzierzak, Martin A. M. Reijns, Duncan Sproul, Andrew P. Jackson

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DOI: 10.1038/s41588-026-02633-8
Published: 2026-06-12
Container: Nature Genetics
Publisher: Springer Science and Business Media LLC
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Cite this work

BibTeX

@article{allodium:10.1038/s41588-026-02633-8,
title = {A progeria syndrome links DNA hypermethylation to age-related pathology},
author = {Dan Sarni and Gráinne Neary and Paula L. Carroll and Chris S. Vink and Caroline V. Billard and Tomoya Isobe and Xiong Weng and Jordan R. Portman and Daniel L. McCartney and Patricia Heyn and Rob J. van ‘t Hof and Linda R. Morrison and Carol-Anne Martin and Colin Stok and Margaret E. Harley and Andrea Leitch and Maarten van den Ancker and Nic Robertson and Laura Kitto and Richard Clark and Michael Rennie and Anna Popravko and Jessica J. McClure and David A. Parry and Giuseppina Camiolo and Tom Leah and Hélène Jakobczyk and Roly Megaw and Lisa McKie and Grant F. Marshall and Nika Balkic and Jeanne Amiel and Tania Barragán Arévalo and Grace Bronken McCarthy and Catherine A. Buchanan and Alexandre Buffet and Alberto Cascón and Benjamin Cogne and Solene Conrad and Anna Maria Cueto-González and Maria Currás-Freixes and Gunnar Douzgos Houge and Chin-To Fong and Jaya K. George-Abraham and Kate Gibson and Lourdes Ibáñez and Nicola Longo and Charlotte Lussey-Lepoutre and Bradley S. Miller and Alejandro Moles-Fernandez and Nishitha R. Pillai and Tatiana Tvrdik and Marie Vincent and Emiy Yokoyama and Catherine M. Abbott and Francisco Jose Sanchez-Luque and Katrin Ottersbach and Cosimo De Bari and Anke J. Roelofs and Rebekah Tillotson and Kamil R. Kranc and Sara J. Brown and Riccardo E. Marioni and Mihaela Crisan and Berthold Göttgens and Neil C. Henderson and Robert K. Semple and Kevin B. Myant and Elaine Dzierzak and Martin A. M. Reijns and Duncan Sproul and Andrew P. Jackson},
year = {2026},
journal = {Nature Genetics},
doi = {10.1038/s41588-026-02633-8},
url = {https://doi.org/10.1038/s41588-026-02633-8}
}

RIS

TY  - JOUR
TI  - A progeria syndrome links DNA hypermethylation to age-related pathology
AU  - Dan Sarni
AU  - Gráinne Neary
AU  - Paula L. Carroll
AU  - Chris S. Vink
AU  - Caroline V. Billard
AU  - Tomoya Isobe
AU  - Xiong Weng
AU  - Jordan R. Portman
AU  - Daniel L. McCartney
AU  - Patricia Heyn
AU  - Rob J. van ‘t Hof
AU  - Linda R. Morrison
AU  - Carol-Anne Martin
AU  - Colin Stok
AU  - Margaret E. Harley
AU  - Andrea Leitch
AU  - Maarten van den Ancker
AU  - Nic Robertson
AU  - Laura Kitto
AU  - Richard Clark
AU  - Michael Rennie
AU  - Anna Popravko
AU  - Jessica J. McClure
AU  - David A. Parry
AU  - Giuseppina Camiolo
AU  - Tom Leah
AU  - Hélène Jakobczyk
AU  - Roly Megaw
AU  - Lisa McKie
AU  - Grant F. Marshall
AU  - Nika Balkic
AU  - Jeanne Amiel
AU  - Tania Barragán Arévalo
AU  - Grace Bronken McCarthy
AU  - Catherine A. Buchanan
AU  - Alexandre Buffet
AU  - Alberto Cascón
AU  - Benjamin Cogne
AU  - Solene Conrad
AU  - Anna Maria Cueto-González
AU  - Maria Currás-Freixes
AU  - Gunnar Douzgos Houge
AU  - Chin-To Fong
AU  - Jaya K. George-Abraham
AU  - Kate Gibson
AU  - Lourdes Ibáñez
AU  - Nicola Longo
AU  - Charlotte Lussey-Lepoutre
AU  - Bradley S. Miller
AU  - Alejandro Moles-Fernandez
AU  - Nishitha R. Pillai
AU  - Tatiana Tvrdik
AU  - Marie Vincent
AU  - Emiy Yokoyama
AU  - Catherine M. Abbott
AU  - Francisco Jose Sanchez-Luque
AU  - Katrin Ottersbach
AU  - Cosimo De Bari
AU  - Anke J. Roelofs
AU  - Rebekah Tillotson
AU  - Kamil R. Kranc
AU  - Sara J. Brown
AU  - Riccardo E. Marioni
AU  - Mihaela Crisan
AU  - Berthold Göttgens
AU  - Neil C. Henderson
AU  - Robert K. Semple
AU  - Kevin B. Myant
AU  - Elaine Dzierzak
AU  - Martin A. M. Reijns
AU  - Duncan Sproul
AU  - Andrew P. Jackson
PY  - 2026
JO  - Nature Genetics
DO  - 10.1038/s41588-026-02633-8
UR  - https://doi.org/10.1038/s41588-026-02633-8
ER  -

APA

Sarni, D., Neary, G., Carroll, P. L., Vink, C. S., Billard, C. V., Isobe, T., Weng, X., Portman, J. R., McCartney, D. L., Heyn, P., Hof, R. J. V. ‘., Morrison, L. R., Martin, C., Stok, C., Harley, M. E., Leitch, A., Ancker, M. V. D., Robertson, N., Kitto, L., Clark, R., Rennie, M., Popravko, A., McClure, J. J., Parry, D. A., Camiolo, G., Leah, T., Jakobczyk, H., Megaw, R., McKie, L., Marshall, G. F., Balkic, N., Amiel, J., Arévalo, T. B., McCarthy, G. B., Buchanan, C. A., Buffet, A., Cascón, A., Cogne, B., Conrad, S., Cueto-González, A. M., Currás-Freixes, M., Houge, G. D., Fong, C., George-Abraham, J. K., Gibson, K., Ibáñez, L., Longo, N., Lussey-Lepoutre, C., Miller, B. S., Moles-Fernandez, A., Pillai, N. R., Tvrdik, T., Vincent, M., Yokoyama, E., Abbott, C. M., Sanchez-Luque, F. J., Ottersbach, K., Bari, C. D., Roelofs, A. J., Tillotson, R., Kranc, K. R., Brown, S. J., Marioni, R. E., Crisan, M., Göttgens, B., Henderson, N. C., Semple, R. K., Myant, K. B., Dzierzak, E., Reijns, M. A. M., Sproul, D., & Jackson, A. P. (2026). A progeria syndrome links DNA hypermethylation to age-related pathology. Nature Genetics. https://doi.org/10.1038/s41588-026-02633-8

Source records

crossref · retrieved 2026-09-25T17:59:08.035Z