APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease.

Thomassen JQ, Leonard H, Ulms B, Grenier-Boley B, Heikkinen S, Garcia-González P, Castillo-Morales A, Kikuchi M, Gim J, Cao H, Küçükali F, Amin N, Yoon D, de Rojas I, Alvarez Jerez P, Alvarez V, Arosio B, Bellenguez C, Bergh S, Billingsley K, Blauwendraat C, Boada M, Borroni B, Bossù P, Bullido MJ, Daniele A, Carracedo Á, de Mendonça A, Cookson M, Deckert J, Dichgans M, Djurovic S, Dols-Icardo O, Dufouil C, Düzel E, Escott-Price V, Fladby T, Fratiglioni L, Fu AKY, Galimberti D, García-Alberca JM, Giedraitis V, Garcia-Ribas G, Graff C, Grimmer T, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Hort J, Jessen F, Jensen K, Jonson C, Kim Y, Kuznetsov N, Leinonen V, Lipponen A, Luo J, Makarious M, Martiskainen H, Masullo C, Mecocci P, Mehrabian S, Mir P, Miyashita A, Moebus S, Mok KY, Molina Porcel L, Moreno F, Nacmias B, Parnetti L, Pastor P, Pérez-Tur J, Peters O, Pijnenburg YAL, Piñol-Ripoll G, Popp J, Rainero I, Real LM, Riedel-Heller S, Rodriguez-Rodriguez E, Rongve A, Rossi G, Royo JL, Rujescu D, Saltvedt I, Sáez ME, Sánchez-Valle R, Sanchez-Garcia F, Sandau N, Scarmeas N, Scheffler K, Scherbaum N, Schneider A, Selbæk G, Seripa D, Solfrizzi V, Spallazzi M, Squassina A, Stordal E, Tesi N, Tremolizzo L, Tripathi KP, van der Flier WM, Williams J, Wiltfang J, Aarsland D, Singleton AB, Amouyel P, Debette S, Tsolaki M, Nicolas G, van der Lee S, Holstege H, Fernandez MV, Kehoe PG, Sleegers K, Ingelsson M, Ghidoni R, Andreassen OA, Holmans PA, Sánchez-Juan P, Sims R, Ip NY, Lee KH, Ikeuchi T, Ramirez A, Ruiz A, Hiltunen M, Lambert JC, van Duijn C, Nalls M, Frikke-Schmidt R

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DOI
10.1038/s41588-026-02713-9
Published
2026 Sep 14
Container
Nature genetics
Publisher
Not recorded
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BibTeX

@article{allodium:10.1038/s41588-026-02713-9,
  title = {APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease.},
  author = {Thomassen JQ and Leonard H and Ulms B and Grenier-Boley B and Heikkinen S and Garcia-González P and Castillo-Morales A and Kikuchi M and Gim J and Cao H and Küçükali F and Amin N and Yoon D and de Rojas I and Alvarez Jerez P and Alvarez V and Arosio B and Bellenguez C and Bergh S and Billingsley K and Blauwendraat C and Boada M and Borroni B and Bossù P and Bullido MJ and Daniele A and Carracedo Á and de Mendonça A and Cookson M and Deckert J and Dichgans M and Djurovic S and Dols-Icardo O and Dufouil C and Düzel E and Escott-Price V and Fladby T and Fratiglioni L and Fu AKY and Galimberti D and García-Alberca JM and Giedraitis V and Garcia-Ribas G and Graff C and Grimmer T and Grünblatt E and Hanon O and Hausner L and Heilmann-Heimbach S and Hort J and Jessen F and Jensen K and Jonson C and Kim Y and Kuznetsov N and Leinonen V and Lipponen A and Luo J and Makarious M and Martiskainen H and Masullo C and Mecocci P and Mehrabian S and Mir P and Miyashita A and Moebus S and Mok KY and Molina Porcel L and Moreno F and Nacmias B and Parnetti L and Pastor P and Pérez-Tur J and Peters O and Pijnenburg YAL and Piñol-Ripoll G and Popp J and Rainero I and Real LM and Riedel-Heller S and Rodriguez-Rodriguez E and Rongve A and Rossi G and Royo JL and Rujescu D and Saltvedt I and Sáez ME and Sánchez-Valle R and Sanchez-Garcia F and Sandau N and Scarmeas N and Scheffler K and Scherbaum N and Schneider A and Selbæk G and Seripa D and Solfrizzi V and Spallazzi M and Squassina A and Stordal E and Tesi N and Tremolizzo L and Tripathi KP and van der Flier WM and Williams J and Wiltfang J and Aarsland D and Singleton AB and Amouyel P and Debette S and Tsolaki M and Nicolas G and van der Lee S and Holstege H and Fernandez MV and Kehoe PG and Sleegers K and Ingelsson M and Ghidoni R and Andreassen OA and Holmans PA and Sánchez-Juan P and Sims R and Ip NY and Lee KH and Ikeuchi T and Ramirez A and Ruiz A and Hiltunen M and Lambert JC and van Duijn C and Nalls M and Frikke-Schmidt R},
  year = {2026},
  journal = {Nature genetics},
  doi = {10.1038/s41588-026-02713-9},
  url = {https://doi.org/10.1038/s41588-026-02713-9}
}

RIS

TY  - JOUR
TI  - APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease.
AU  - Thomassen JQ
AU  - Leonard H
AU  - Ulms B
AU  - Grenier-Boley B
AU  - Heikkinen S
AU  - Garcia-González P
AU  - Castillo-Morales A
AU  - Kikuchi M
AU  - Gim J
AU  - Cao H
AU  - Küçükali F
AU  - Amin N
AU  - Yoon D
AU  - de Rojas I
AU  - Alvarez Jerez P
AU  - Alvarez V
AU  - Arosio B
AU  - Bellenguez C
AU  - Bergh S
AU  - Billingsley K
AU  - Blauwendraat C
AU  - Boada M
AU  - Borroni B
AU  - Bossù P
AU  - Bullido MJ
AU  - Daniele A
AU  - Carracedo Á
AU  - de Mendonça A
AU  - Cookson M
AU  - Deckert J
AU  - Dichgans M
AU  - Djurovic S
AU  - Dols-Icardo O
AU  - Dufouil C
AU  - Düzel E
AU  - Escott-Price V
AU  - Fladby T
AU  - Fratiglioni L
AU  - Fu AKY
AU  - Galimberti D
AU  - García-Alberca JM
AU  - Giedraitis V
AU  - Garcia-Ribas G
AU  - Graff C
AU  - Grimmer T
AU  - Grünblatt E
AU  - Hanon O
AU  - Hausner L
AU  - Heilmann-Heimbach S
AU  - Hort J
AU  - Jessen F
AU  - Jensen K
AU  - Jonson C
AU  - Kim Y
AU  - Kuznetsov N
AU  - Leinonen V
AU  - Lipponen A
AU  - Luo J
AU  - Makarious M
AU  - Martiskainen H
AU  - Masullo C
AU  - Mecocci P
AU  - Mehrabian S
AU  - Mir P
AU  - Miyashita A
AU  - Moebus S
AU  - Mok KY
AU  - Molina Porcel L
AU  - Moreno F
AU  - Nacmias B
AU  - Parnetti L
AU  - Pastor P
AU  - Pérez-Tur J
AU  - Peters O
AU  - Pijnenburg YAL
AU  - Piñol-Ripoll G
AU  - Popp J
AU  - Rainero I
AU  - Real LM
AU  - Riedel-Heller S
AU  - Rodriguez-Rodriguez E
AU  - Rongve A
AU  - Rossi G
AU  - Royo JL
AU  - Rujescu D
AU  - Saltvedt I
AU  - Sáez ME
AU  - Sánchez-Valle R
AU  - Sanchez-Garcia F
AU  - Sandau N
AU  - Scarmeas N
AU  - Scheffler K
AU  - Scherbaum N
AU  - Schneider A
AU  - Selbæk G
AU  - Seripa D
AU  - Solfrizzi V
AU  - Spallazzi M
AU  - Squassina A
AU  - Stordal E
AU  - Tesi N
AU  - Tremolizzo L
AU  - Tripathi KP
AU  - van der Flier WM
AU  - Williams J
AU  - Wiltfang J
AU  - Aarsland D
AU  - Singleton AB
AU  - Amouyel P
AU  - Debette S
AU  - Tsolaki M
AU  - Nicolas G
AU  - van der Lee S
AU  - Holstege H
AU  - Fernandez MV
AU  - Kehoe PG
AU  - Sleegers K
AU  - Ingelsson M
AU  - Ghidoni R
AU  - Andreassen OA
AU  - Holmans PA
AU  - Sánchez-Juan P
AU  - Sims R
AU  - Ip NY
AU  - Lee KH
AU  - Ikeuchi T
AU  - Ramirez A
AU  - Ruiz A
AU  - Hiltunen M
AU  - Lambert JC
AU  - van Duijn C
AU  - Nalls M
AU  - Frikke-Schmidt R
PY  - 2026
JO  - Nature genetics
DO  - 10.1038/s41588-026-02713-9
UR  - https://doi.org/10.1038/s41588-026-02713-9
ER  -

APA

JQ, T., H, L., B, U., B, G., S, H., P, G., A, C., M, K., J, G., H, C., F, K., N, A., D, Y., I, D. R., P, A. J., V, A., B, A., C, B., S, B., K, B., C, B., M, B., B, B., P, B., MJ, B., A, D., Á, C., A, D. M., M, C., J, D., M, D., S, D., O, D., C, D., E, D., V, E., T, F., L, F., AKY, F., D, G., JM, G., V, G., G, G., C, G., T, G., E, G., O, H., L, H., S, H., J, H., F, J., K, J., C, J., Y, K., N, K., V, L., A, L., J, L., M, M., H, M., C, M., P, M., S, M., P, M., A, M., S, M., KY, M., L, M. P., F, M., B, N., L, P., P, P., J, P., O, P., YAL, P., G, P., J, P., I, R., LM, R., S, R., E, R., A, R., G, R., JL, R., D, R., I, S., ME, S., R, S., F, S., N, S., N, S., K, S., N, S., A, S., G, S., D, S., V, S., M, S., A, S., E, S., N, T., L, T., KP, T., WM, V. D. F., J, W., J, W., D, A., AB, S., P, A., S, D., M, T., G, N., S, V. D. L., H, H., MV, F., PG, K., K, S., M, I., R, G., OA, A., PA, H., P, S., R, S., NY, I., KH, L., T, I., A, R., A, R., M, H., JC, L., C, V. D., M, N., & R, F. (2026). APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease.. Nature genetics. https://doi.org/10.1038/s41588-026-02713-9

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