A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations.

Kurniansyah N, Tasaki S, Rehman H, Zhu C, Farrell J, Sherva R, Hauger R, Merritt VC, Panizzon M, Zhang R, Gaziano JM, Gim J, Lee K, Lee DY, Nho K, Vialle RA, Mukherjee S, Trittschuh EH, Lee AJ, Brickman AM, Cruchaga C, Risacher S, Greve DN, Crane P, Martin E, Bush WS, Mayeux R, Haines JL, Pericak-Vance MA, Logue M, Bennett DA, Barnes LL, Saykin A, Hohman T, Wang LS, Schellenberg GD, Ang TFA, Au R, Mez J, Lunetta KL, Zhang X, Farrer LA

Open source

DOI
10.1038/s41588-026-02722-8
Published
2026 Sep
Container
Nature genetics
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41588-026-02722-8,
  title = {A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations.},
  author = {Kurniansyah N and Tasaki S and Rehman H and Zhu C and Farrell J and Sherva R and Hauger R and Merritt VC and Panizzon M and Zhang R and Gaziano JM and Gim J and Lee K and Lee DY and Nho K and Vialle RA and Mukherjee S and Trittschuh EH and Lee AJ and Brickman AM and Cruchaga C and Risacher S and Greve DN and Crane P and Martin E and Bush WS and Mayeux R and Haines JL and Pericak-Vance MA and Logue M and Bennett DA and Barnes LL and Saykin A and Hohman T and Wang LS and Schellenberg GD and Ang TFA and Au R and Mez J and Lunetta KL and Zhang X and Farrer LA},
  year = {2026},
  journal = {Nature genetics},
  doi = {10.1038/s41588-026-02722-8},
  url = {https://doi.org/10.1038/s41588-026-02722-8}
}

RIS

TY  - JOUR
TI  - A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations.
AU  - Kurniansyah N
AU  - Tasaki S
AU  - Rehman H
AU  - Zhu C
AU  - Farrell J
AU  - Sherva R
AU  - Hauger R
AU  - Merritt VC
AU  - Panizzon M
AU  - Zhang R
AU  - Gaziano JM
AU  - Gim J
AU  - Lee K
AU  - Lee DY
AU  - Nho K
AU  - Vialle RA
AU  - Mukherjee S
AU  - Trittschuh EH
AU  - Lee AJ
AU  - Brickman AM
AU  - Cruchaga C
AU  - Risacher S
AU  - Greve DN
AU  - Crane P
AU  - Martin E
AU  - Bush WS
AU  - Mayeux R
AU  - Haines JL
AU  - Pericak-Vance MA
AU  - Logue M
AU  - Bennett DA
AU  - Barnes LL
AU  - Saykin A
AU  - Hohman T
AU  - Wang LS
AU  - Schellenberg GD
AU  - Ang TFA
AU  - Au R
AU  - Mez J
AU  - Lunetta KL
AU  - Zhang X
AU  - Farrer LA
PY  - 2026
JO  - Nature genetics
DO  - 10.1038/s41588-026-02722-8
UR  - https://doi.org/10.1038/s41588-026-02722-8
ER  - 

APA

N, K., S, T., H, R., C, Z., J, F., R, S., R, H., VC, M., M, P., R, Z., JM, G., J, G., K, L., DY, L., K, N., RA, V., S, M., EH, T., AJ, L., AM, B., C, C., S, R., DN, G., P, C., E, M., WS, B., R, M., JL, H., MA, P., M, L., DA, B., LL, B., A, S., T, H., LS, W., GD, S., TFA, A., R, A., J, M., KL, L., X, Z., & LA, F. (2026). A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations.. Nature genetics. https://doi.org/10.1038/s41588-026-02722-8

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