CA-IV-directed small-molecule shuttle enables targeted brain delivery of biologics

Xiaozhe Ding, Xinhong Chen, Philip Boehm, Alba Carretero-Cerdán, Seongmin Jang, Erin E. Sullivan, Cynthia M. Arokiaraj, Fiona Ristic, Bill C. Kavvathas, Lillian J. Campos, Jitendra Sharma, Shawn Kamboj, Yaping Lei, Mona Shahgholi, Danielle Mantin, Andrew S. Fox, Timothy F. Shay, Sarah E. Reisman, Viviana Gradinaru

Open source

DOI
10.1038/s41589-026-02294-y
Published
2026-08-26
Container
Nature Chemical Biology
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s41589-026-02294-y,
  title = {CA-IV-directed small-molecule shuttle enables targeted brain delivery of biologics},
  author = {Xiaozhe Ding and Xinhong Chen and Philip Boehm and Alba Carretero-Cerdán and Seongmin Jang and Erin E. Sullivan and Cynthia M. Arokiaraj and Fiona Ristic and Bill C. Kavvathas and Lillian J. Campos and Jitendra Sharma and Shawn Kamboj and Yaping Lei and Mona Shahgholi and Danielle Mantin and Andrew S. Fox and Timothy F. Shay and Sarah E. Reisman and Viviana Gradinaru},
  year = {2026},
  journal = {Nature Chemical Biology},
  doi = {10.1038/s41589-026-02294-y},
  url = {https://doi.org/10.1038/s41589-026-02294-y}
}

RIS

TY  - JOUR
TI  - CA-IV-directed small-molecule shuttle enables targeted brain delivery of biologics
AU  - Xiaozhe Ding
AU  - Xinhong Chen
AU  - Philip Boehm
AU  - Alba Carretero-Cerdán
AU  - Seongmin Jang
AU  - Erin E. Sullivan
AU  - Cynthia M. Arokiaraj
AU  - Fiona Ristic
AU  - Bill C. Kavvathas
AU  - Lillian J. Campos
AU  - Jitendra Sharma
AU  - Shawn Kamboj
AU  - Yaping Lei
AU  - Mona Shahgholi
AU  - Danielle Mantin
AU  - Andrew S. Fox
AU  - Timothy F. Shay
AU  - Sarah E. Reisman
AU  - Viviana Gradinaru
PY  - 2026
JO  - Nature Chemical Biology
DO  - 10.1038/s41589-026-02294-y
UR  - https://doi.org/10.1038/s41589-026-02294-y
ER  - 

APA

Ding, X., Chen, X., Boehm, P., Carretero-Cerdán, A., Jang, S., Sullivan, E. E., Arokiaraj, C. M., Ristic, F., Kavvathas, B. C., Campos, L. J., Sharma, J., Kamboj, S., Lei, Y., Shahgholi, M., Mantin, D., Fox, A. S., Shay, T. F., Reisman, S. E., & Gradinaru, V. (2026). CA-IV-directed small-molecule shuttle enables targeted brain delivery of biologics. Nature Chemical Biology. https://doi.org/10.1038/s41589-026-02294-y

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