A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial

Chang Liu, Dan Liu, Yinghua Ji, Meili Sun, Shegan Gao, Xuelei Ma, Diansheng Zhong, Ji Zhu, Yanshuo Cao, Changsong Qi, Miao Zhang, Panpan Zhang, Ran Xue, Zhi Peng, Jun Zhou, Sai Ge, Ming Lu, Jiajia Yuan, Yakun Wang, Zhenghang Wang, Jian Li, Xiaotian Zhang, Yi Zhu, Hai Zhu, Sa Xiao, Jifang Gong, Lin Shen, Zhihao Lu

Open source

DOI: 10.1038/s41591-025-03792-7
Published: 2025-07-10
Container: Nature Medicine
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41591-025-03792-7,
  title = {A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial},
  author = {Chang Liu and Dan Liu and Yinghua Ji and Meili Sun and Shegan Gao and Xuelei Ma and Diansheng Zhong and Ji Zhu and Yanshuo Cao and Changsong Qi and Miao Zhang and Panpan Zhang and Ran Xue and Zhi Peng and Jun Zhou and Sai Ge and Ming Lu and Jiajia Yuan and Yakun Wang and Zhenghang Wang and Jian Li and Xiaotian Zhang and Yi Zhu and Hai Zhu and Sa Xiao and Jifang Gong and Lin Shen and Zhihao Lu},
  year = {2025},
  journal = {Nature Medicine},
  doi = {10.1038/s41591-025-03792-7},
  url = {https://doi.org/10.1038/s41591-025-03792-7}
}

RIS

TY  - JOUR
TI  - A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial
AU  - Chang Liu
AU  - Dan Liu
AU  - Yinghua Ji
AU  - Meili Sun
AU  - Shegan Gao
AU  - Xuelei Ma
AU  - Diansheng Zhong
AU  - Ji Zhu
AU  - Yanshuo Cao
AU  - Changsong Qi
AU  - Miao Zhang
AU  - Panpan Zhang
AU  - Ran Xue
AU  - Zhi Peng
AU  - Jun Zhou
AU  - Sai Ge
AU  - Ming Lu
AU  - Jiajia Yuan
AU  - Yakun Wang
AU  - Zhenghang Wang
AU  - Jian Li
AU  - Xiaotian Zhang
AU  - Yi Zhu
AU  - Hai Zhu
AU  - Sa Xiao
AU  - Jifang Gong
AU  - Lin Shen
AU  - Zhihao Lu
PY  - 2025
JO  - Nature Medicine
DO  - 10.1038/s41591-025-03792-7
UR  - https://doi.org/10.1038/s41591-025-03792-7
ER  -

APA

Liu, C., Liu, D., Ji, Y., Sun, M., Gao, S., Ma, X., Zhong, D., Zhu, J., Cao, Y., Qi, C., Zhang, M., Zhang, P., Xue, R., Peng, Z., Zhou, J., Ge, S., Lu, M., Yuan, J., Wang, Y., Wang, Z., Li, J., Zhang, X., Zhu, Y., Zhu, H., Xiao, S., Gong, J., Shen, L., & Lu, Z. (2025). A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial. Nature Medicine. https://doi.org/10.1038/s41591-025-03792-7

Source records

crossref · retrieved 2026-09-27T10:06:49.060Z