BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial

Tuan Vu, Hacer Durmus, Michael Rivner, Sheetal Shroff, Thomas Ragole, Bennett Myers, Mamatha Pasnoor, George Small, Chafic Karam, Mithila Vullaganti, Amanda Peltier, Gregory Sahagian, Marc H. Feinberg, Adam Slanksy, Carolina Barnett-Tapia, Zaeem Siddiqi, Kelly Gwathmey, Michael A. Badruddoja, Hafsa Kamboh, Rachel N. Ruggerie, Renee R. Fedak, C. Andrew Stewart, Metin Kurtoglu, Murat Kalayoglu, Michael Singer, Christopher M. Jewell, Milos D. Miljkovic, Mazen Dimachkie, Tahseen Mozaffar, James F. Howard, Unknown

Open source

DOI: 10.1038/s41591-025-04171-y
Published: 2026-01-09
Container: Nature Medicine
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41591-025-04171-y,
  title = {BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial},
  author = {Tuan Vu and Hacer Durmus and Michael Rivner and Sheetal Shroff and Thomas Ragole and Bennett Myers and Mamatha Pasnoor and George Small and Chafic Karam and Mithila Vullaganti and Amanda Peltier and Gregory Sahagian and Marc H. Feinberg and Adam Slanksy and Carolina Barnett-Tapia and Zaeem Siddiqi and Kelly Gwathmey and Michael A. Badruddoja and Hafsa Kamboh and Rachel N. Ruggerie and Renee R. Fedak and C. Andrew Stewart and Metin Kurtoglu and Murat Kalayoglu and Michael Singer and Christopher M. Jewell and Milos D. Miljkovic and Mazen Dimachkie and Tahseen Mozaffar and James F. Howard and Unknown},
  year = {2026},
  journal = {Nature Medicine},
  doi = {10.1038/s41591-025-04171-y},
  url = {https://doi.org/10.1038/s41591-025-04171-y}
}

RIS

TY  - JOUR
TI  - BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial
AU  - Tuan Vu
AU  - Hacer Durmus
AU  - Michael Rivner
AU  - Sheetal Shroff
AU  - Thomas Ragole
AU  - Bennett Myers
AU  - Mamatha Pasnoor
AU  - George Small
AU  - Chafic Karam
AU  - Mithila Vullaganti
AU  - Amanda Peltier
AU  - Gregory Sahagian
AU  - Marc H. Feinberg
AU  - Adam Slanksy
AU  - Carolina Barnett-Tapia
AU  - Zaeem Siddiqi
AU  - Kelly Gwathmey
AU  - Michael A. Badruddoja
AU  - Hafsa Kamboh
AU  - Rachel N. Ruggerie
AU  - Renee R. Fedak
AU  - C. Andrew Stewart
AU  - Metin Kurtoglu
AU  - Murat Kalayoglu
AU  - Michael Singer
AU  - Christopher M. Jewell
AU  - Milos D. Miljkovic
AU  - Mazen Dimachkie
AU  - Tahseen Mozaffar
AU  - James F. Howard
AU  - Unknown
PY  - 2026
JO  - Nature Medicine
DO  - 10.1038/s41591-025-04171-y
UR  - https://doi.org/10.1038/s41591-025-04171-y
ER  -

APA

Vu, T., Durmus, H., Rivner, M., Shroff, S., Ragole, T., Myers, B., Pasnoor, M., Small, G., Karam, C., Vullaganti, M., Peltier, A., Sahagian, G., Feinberg, M. H., Slanksy, A., Barnett-Tapia, C., Siddiqi, Z., Gwathmey, K., Badruddoja, M. A., Kamboh, H., Ruggerie, R. N., Fedak, R. R., Stewart, C. A., Kurtoglu, M., Kalayoglu, M., Singer, M., Jewell, C. M., Miljkovic, M. D., Dimachkie, M., Mozaffar, T., Howard, J. F., & Unknown (2026). BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial. Nature Medicine. https://doi.org/10.1038/s41591-025-04171-y

Source records

crossref · retrieved 2026-09-26T10:16:01.412Z