Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC.

Prelaj A, Miskovic V, Sacco M, Ferrarin A, Licciardello CM, Provenzano L, Favali M, Lerma L, Zec A, Spagnoletti A, Ganzinelli M, Lorenzini D, Guirges B, Invernizzi L, Silvestri C, Mazzeo L, Prina MM, Corrao G, Ruggirello M, Dumitrascu AD, Di Mauro RM, Monzani D, Pravettoni G, Zanitti M, Macocchi D, Marino MB, Cavalli C, Romanò R, Giani C, Armato SG 3rd, Esposito A, Bestvina CM, Spector M, Naama BR, Basheer R, Hafzadi AL, Roisman L, Watermann I, Szewczyk M, Olchers T, Richter H, Blanke-Roeser C, Siniscalchi C, Di Lello A, Arangoa T, Bartolomeo V, Spathas N, Sarris E, Fountzilas E, Roca AA, Caro-Consuegra R, Iranzo P, Fernández-Pinto M, Rodríguez-Morató J, Agnelli L, Occhipinti M, Brambilla M, Beninato T, Proto C, Kosta S, Di Palma MP, Rulli E, Steurer S, Simon R, Willis M, Pruneri G, De Braud F, Restelli M, Felip E, Peled N, Pearson AT, Linardou H, Reck M, Russo GL, Trovò F, Pedrocchi ALG, Garassino MC, I3LUNG Consortium

Open source

DOI: 10.1038/s41591-026-04488-2
Published: 2026 Sep
Container: Nature medicine
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41591-026-04488-2,
  title = {Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC.},
  author = {Prelaj A and Miskovic V and Sacco M and Ferrarin A and Licciardello CM and Provenzano L and Favali M and Lerma L and Zec A and Spagnoletti A and Ganzinelli M and Lorenzini D and Guirges B and Invernizzi L and Silvestri C and Mazzeo L and Prina MM and Corrao G and Ruggirello M and Dumitrascu AD and Di Mauro RM and Monzani D and Pravettoni G and Zanitti M and Macocchi D and Marino MB and Cavalli C and Romanò R and Giani C and Armato SG 3rd and Esposito A and Bestvina CM and Spector M and Naama BR and Basheer R and Hafzadi AL and Roisman L and Watermann I and Szewczyk M and Olchers T and Richter H and Blanke-Roeser C and Siniscalchi C and Di Lello A and Arangoa T and Bartolomeo V and Spathas N and Sarris E and Fountzilas E and Roca AA and Caro-Consuegra R and Iranzo P and Fernández-Pinto M and Rodríguez-Morató J and Agnelli L and Occhipinti M and Brambilla M and Beninato T and Proto C and Kosta S and Di Palma MP and Rulli E and Steurer S and Simon R and Willis M and Pruneri G and De Braud F and Restelli M and Felip E and Peled N and Pearson AT and Linardou H and Reck M and Russo GL and Trovò F and Pedrocchi ALG and Garassino MC and I3LUNG Consortium},
  year = {2026},
  journal = {Nature medicine},
  doi = {10.1038/s41591-026-04488-2},
  url = {https://doi.org/10.1038/s41591-026-04488-2}
}

RIS

TY  - JOUR
TI  - Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC.
AU  - Prelaj A
AU  - Miskovic V
AU  - Sacco M
AU  - Ferrarin A
AU  - Licciardello CM
AU  - Provenzano L
AU  - Favali M
AU  - Lerma L
AU  - Zec A
AU  - Spagnoletti A
AU  - Ganzinelli M
AU  - Lorenzini D
AU  - Guirges B
AU  - Invernizzi L
AU  - Silvestri C
AU  - Mazzeo L
AU  - Prina MM
AU  - Corrao G
AU  - Ruggirello M
AU  - Dumitrascu AD
AU  - Di Mauro RM
AU  - Monzani D
AU  - Pravettoni G
AU  - Zanitti M
AU  - Macocchi D
AU  - Marino MB
AU  - Cavalli C
AU  - Romanò R
AU  - Giani C
AU  - Armato SG 3rd
AU  - Esposito A
AU  - Bestvina CM
AU  - Spector M
AU  - Naama BR
AU  - Basheer R
AU  - Hafzadi AL
AU  - Roisman L
AU  - Watermann I
AU  - Szewczyk M
AU  - Olchers T
AU  - Richter H
AU  - Blanke-Roeser C
AU  - Siniscalchi C
AU  - Di Lello A
AU  - Arangoa T
AU  - Bartolomeo V
AU  - Spathas N
AU  - Sarris E
AU  - Fountzilas E
AU  - Roca AA
AU  - Caro-Consuegra R
AU  - Iranzo P
AU  - Fernández-Pinto M
AU  - Rodríguez-Morató J
AU  - Agnelli L
AU  - Occhipinti M
AU  - Brambilla M
AU  - Beninato T
AU  - Proto C
AU  - Kosta S
AU  - Di Palma MP
AU  - Rulli E
AU  - Steurer S
AU  - Simon R
AU  - Willis M
AU  - Pruneri G
AU  - De Braud F
AU  - Restelli M
AU  - Felip E
AU  - Peled N
AU  - Pearson AT
AU  - Linardou H
AU  - Reck M
AU  - Russo GL
AU  - Trovò F
AU  - Pedrocchi ALG
AU  - Garassino MC
AU  - I3LUNG Consortium
PY  - 2026
JO  - Nature medicine
DO  - 10.1038/s41591-026-04488-2
UR  - https://doi.org/10.1038/s41591-026-04488-2
ER  -

APA

A, P., V, M., M, S., A, F., CM, L., L, P., M, F., L, L., A, Z., A, S., M, G., D, L., B, G., L, I., C, S., L, M., MM, P., G, C., M, R., AD, D., RM, D. M., D, M., G, P., M, Z., D, M., MB, M., C, C., R, R., C, G., 3rd, A. S., A, E., CM, B., M, S., BR, N., R, B., AL, H., L, R., I, W., M, S., T, O., H, R., C, B., C, S., A, D. L., T, A., V, B., N, S., E, S., E, F., AA, R., R, C., P, I., M, F., J, R., L, A., M, O., M, B., T, B., C, P., S, K., MP, D. P., E, R., S, S., R, S., M, W., G, P., F, D. B., M, R., E, F., N, P., AT, P., H, L., M, R., GL, R., F, T., ALG, P., MC, G., & Consortium, I. (2026). Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC.. Nature medicine. https://doi.org/10.1038/s41591-026-04488-2

Source records

pubmed · retrieved 2026-09-25T11:41:53.889Z