KRAS-G12D inhibitor HRS-4642 plus chemotherapy in advanced KRASG12D-mutant pancreatic cancer: a phase 1b/2 trial

Jiujie Cui, Kuirong Jiang, Wei Li, Shuqin Ni, Hong Zong, Juan Du, Yifu He, Zhonghua Liu, Guoqiang Kong, Yanqiao Zhang, Xiaotong Li, Hongxia Han, Fen Yao, Yongwu Chen, Ming Zhou, Liwei Wang

Open source

DOI
10.1038/s41591-026-04538-9
Published
2026-07-09
Container
Nature Medicine
Publisher
Springer Science and Business Media LLC
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1038/s41591-026-04538-9,
  title = {KRAS-G12D inhibitor HRS-4642 plus chemotherapy in advanced KRASG12D-mutant pancreatic cancer: a phase 1b/2 trial},
  author = {Jiujie Cui and Kuirong Jiang and Wei Li and Shuqin Ni and Hong Zong and Juan Du and Yifu He and Zhonghua Liu and Guoqiang Kong and Yanqiao Zhang and Xiaotong Li and Hongxia Han and Fen Yao and Yongwu Chen and Ming Zhou and Liwei Wang},
  year = {2026},
  journal = {Nature Medicine},
  doi = {10.1038/s41591-026-04538-9},
  url = {https://doi.org/10.1038/s41591-026-04538-9}
}

RIS

TY  - JOUR
TI  - KRAS-G12D inhibitor HRS-4642 plus chemotherapy in advanced KRASG12D-mutant pancreatic cancer: a phase 1b/2 trial
AU  - Jiujie Cui
AU  - Kuirong Jiang
AU  - Wei Li
AU  - Shuqin Ni
AU  - Hong Zong
AU  - Juan Du
AU  - Yifu He
AU  - Zhonghua Liu
AU  - Guoqiang Kong
AU  - Yanqiao Zhang
AU  - Xiaotong Li
AU  - Hongxia Han
AU  - Fen Yao
AU  - Yongwu Chen
AU  - Ming Zhou
AU  - Liwei Wang
PY  - 2026
JO  - Nature Medicine
DO  - 10.1038/s41591-026-04538-9
UR  - https://doi.org/10.1038/s41591-026-04538-9
ER  - 

APA

Cui, J., Jiang, K., Li, W., Ni, S., Zong, H., Du, J., He, Y., Liu, Z., Kong, G., Zhang, Y., Li, X., Han, H., Yao, F., Chen, Y., Zhou, M., & Wang, L. (2026). KRAS-G12D inhibitor HRS-4642 plus chemotherapy in advanced KRASG12D-mutant pancreatic cancer: a phase 1b/2 trial. Nature Medicine. https://doi.org/10.1038/s41591-026-04538-9

Source records