Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial

James J. Rucker, Tim Mantingh, Jess Kerr-Gaffney, Catherine Bird, Petrina Chu, Nadav Liam Modlin, Kete Campbell-Coker, Sadie Hambleton, Paige Seath, Rebecca Hignett, Diede Fennema, Elliot Hampsey, Dimosthenis Tsapekos, Rebecca J. Thomas, Joseph Cattell, Hassan Jafari, Camilla Day, Anya Borissova, Miranda Lloyd, Theo Boardman-Pretty, Mathieu Seynaeve, Famia Askari, Michael Creed, Luke Baxter, Raphael Rifkin-Zybutz, Matt Butler, Luke A. Jelen, Ben Carter, Allan H. Young

Open source

DOI
10.1038/s41591-026-04541-0
Published
2026-08-06
Container
Nature Medicine
Publisher
Springer Science and Business Media LLC
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1038/s41591-026-04541-0,
  title = {Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial},
  author = {James J. Rucker and Tim Mantingh and Jess Kerr-Gaffney and Catherine Bird and Petrina Chu and Nadav Liam Modlin and Kete Campbell-Coker and Sadie Hambleton and Paige Seath and Rebecca Hignett and Diede Fennema and Elliot Hampsey and Dimosthenis Tsapekos and Rebecca J. Thomas and Joseph Cattell and Hassan Jafari and Camilla Day and Anya Borissova and Miranda Lloyd and Theo Boardman-Pretty and Mathieu Seynaeve and Famia Askari and Michael Creed and Luke Baxter and Raphael Rifkin-Zybutz and Matt Butler and Luke A. Jelen and Ben Carter and Allan H. Young},
  year = {2026},
  journal = {Nature Medicine},
  doi = {10.1038/s41591-026-04541-0},
  url = {https://doi.org/10.1038/s41591-026-04541-0}
}

RIS

TY  - JOUR
TI  - Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial
AU  - James J. Rucker
AU  - Tim Mantingh
AU  - Jess Kerr-Gaffney
AU  - Catherine Bird
AU  - Petrina Chu
AU  - Nadav Liam Modlin
AU  - Kete Campbell-Coker
AU  - Sadie Hambleton
AU  - Paige Seath
AU  - Rebecca Hignett
AU  - Diede Fennema
AU  - Elliot Hampsey
AU  - Dimosthenis Tsapekos
AU  - Rebecca J. Thomas
AU  - Joseph Cattell
AU  - Hassan Jafari
AU  - Camilla Day
AU  - Anya Borissova
AU  - Miranda Lloyd
AU  - Theo Boardman-Pretty
AU  - Mathieu Seynaeve
AU  - Famia Askari
AU  - Michael Creed
AU  - Luke Baxter
AU  - Raphael Rifkin-Zybutz
AU  - Matt Butler
AU  - Luke A. Jelen
AU  - Ben Carter
AU  - Allan H. Young
PY  - 2026
JO  - Nature Medicine
DO  - 10.1038/s41591-026-04541-0
UR  - https://doi.org/10.1038/s41591-026-04541-0
ER  - 

APA

Rucker, J. J., Mantingh, T., Kerr-Gaffney, J., Bird, C., Chu, P., Modlin, N. L., Campbell-Coker, K., Hambleton, S., Seath, P., Hignett, R., Fennema, D., Hampsey, E., Tsapekos, D., Thomas, R. J., Cattell, J., Jafari, H., Day, C., Borissova, A., Lloyd, M., Boardman-Pretty, T., Seynaeve, M., Askari, F., Creed, M., Baxter, L., Rifkin-Zybutz, R., Butler, M., Jelen, L. A., Carter, B., & Young, A. H. (2026). Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial. Nature Medicine. https://doi.org/10.1038/s41591-026-04541-0

Source records