Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study.

Nabavizadeh N, McDonnell C, Kurbegov D, Matrana M, Gadgeel S, Kim RH, Stipec G, Oeffinger KC, Demeure MJ, Lillard JW Jr, Kaltman R, Tran J, Roth A, Tahhan S, Poklepovic A, Richards D, Lopatin M, Marquez C, McCusker M, Giridhar KV

Open source

DOI: 10.1038/s41591-026-04618-w
Published: 2026 Sep 22
Container: Nature medicine
Publisher: Not recorded
Open access: unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41591-026-04618-w,
  title = {Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study.},
  author = {Nabavizadeh N and McDonnell C and Kurbegov D and Matrana M and Gadgeel S and Kim RH and Stipec G and Oeffinger KC and Demeure MJ and Lillard JW Jr and Kaltman R and Tran J and Roth A and Tahhan S and Poklepovic A and Richards D and Lopatin M and Marquez C and McCusker M and Giridhar KV},
  year = {2026},
  journal = {Nature medicine},
  doi = {10.1038/s41591-026-04618-w},
  url = {https://doi.org/10.1038/s41591-026-04618-w}
}

RIS

TY  - JOUR
TI  - Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study.
AU  - Nabavizadeh N
AU  - McDonnell C
AU  - Kurbegov D
AU  - Matrana M
AU  - Gadgeel S
AU  - Kim RH
AU  - Stipec G
AU  - Oeffinger KC
AU  - Demeure MJ
AU  - Lillard JW Jr
AU  - Kaltman R
AU  - Tran J
AU  - Roth A
AU  - Tahhan S
AU  - Poklepovic A
AU  - Richards D
AU  - Lopatin M
AU  - Marquez C
AU  - McCusker M
AU  - Giridhar KV
PY  - 2026
JO  - Nature medicine
DO  - 10.1038/s41591-026-04618-w
UR  - https://doi.org/10.1038/s41591-026-04618-w
ER  -

APA

N, N., C, M., D, K., M, M., S, G., RH, K., G, S., KC, O., MJ, D., Jr, L. J., R, K., J, T., A, R., S, T., A, P., D, R., M, L., C, M., M, M., & KV, G. (2026). Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study.. Nature medicine. https://doi.org/10.1038/s41591-026-04618-w

Source records

pubmed · retrieved 2026-09-26T10:13:54.452Z