Intravenous hyaluronidase-expressing oncolytic adenovirus with chemotherapy in metastatic pancreatic cancer: a randomized phase 2b trial.

Garcia-Carbonero R, Pazo Cid R, Macarulla T, Laquente B, Nguyen A, Guillén-Ponce C, Muñoz A, Kim EJ, Cazorla M, Seery T, Lobo de Mena M, Nevala-Plagemann C, Sharma V, Martínez de Castro E, Hojouj M, Le C, Mato-Berciano A, Connelly S, Kaleko M, Rojas LA, Wacher VJ, Shallcross MA, Blasco C, Cascallo M, Hidalgo M

Open source

DOI
10.1038/s41591-026-04705-y
Published
2026 Sep 30
Container
Nature medicine
Publisher
Not recorded
Open access
unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1038/s41591-026-04705-y,
  title = {Intravenous hyaluronidase-expressing oncolytic adenovirus with chemotherapy in metastatic pancreatic cancer: a randomized phase 2b trial.},
  author = {Garcia-Carbonero R and Pazo Cid R and Macarulla T and Laquente B and Nguyen A and Guillén-Ponce C and Muñoz A and Kim EJ and Cazorla M and Seery T and Lobo de Mena M and Nevala-Plagemann C and Sharma V and Martínez de Castro E and Hojouj M and Le C and Mato-Berciano A and Connelly S and Kaleko M and Rojas LA and Wacher VJ and Shallcross MA and Blasco C and Cascallo M and Hidalgo M},
  year = {2026},
  journal = {Nature medicine},
  doi = {10.1038/s41591-026-04705-y},
  url = {https://doi.org/10.1038/s41591-026-04705-y}
}

RIS

TY  - JOUR
TI  - Intravenous hyaluronidase-expressing oncolytic adenovirus with chemotherapy in metastatic pancreatic cancer: a randomized phase 2b trial.
AU  - Garcia-Carbonero R
AU  - Pazo Cid R
AU  - Macarulla T
AU  - Laquente B
AU  - Nguyen A
AU  - Guillén-Ponce C
AU  - Muñoz A
AU  - Kim EJ
AU  - Cazorla M
AU  - Seery T
AU  - Lobo de Mena M
AU  - Nevala-Plagemann C
AU  - Sharma V
AU  - Martínez de Castro E
AU  - Hojouj M
AU  - Le C
AU  - Mato-Berciano A
AU  - Connelly S
AU  - Kaleko M
AU  - Rojas LA
AU  - Wacher VJ
AU  - Shallcross MA
AU  - Blasco C
AU  - Cascallo M
AU  - Hidalgo M
PY  - 2026
JO  - Nature medicine
DO  - 10.1038/s41591-026-04705-y
UR  - https://doi.org/10.1038/s41591-026-04705-y
ER  - 

APA

R, G., R, P. C., T, M., B, L., A, N., C, G., A, M., EJ, K., M, C., T, S., M, L. D. M., C, N., V, S., E, M. D. C., M, H., C, L., A, M., S, C., M, K., LA, R., VJ, W., MA, S., C, B., M, C., & M, H. (2026). Intravenous hyaluronidase-expressing oncolytic adenovirus with chemotherapy in metastatic pancreatic cancer: a randomized phase 2b trial.. Nature medicine. https://doi.org/10.1038/s41591-026-04705-y

Source records