Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence

Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W. Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L. Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M. B. Breteler, N. Ahmad Aziz, Paolo Salomoni

Open source

DOI: 10.1038/s41593-026-02404-y
Published: 2026-08-17
Container: Nature Neuroscience
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41593-026-02404-y,
  title = {Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence},
  author = {Xin Yan and Christina Georgopoulou and Hang-Mao Lee and Ala Ahrari and Jenny Russ and Vijay Chandrasekar and Tim Ducksch and Giuliano Crispatzu and Valentina Talevi and Liang Qiao and Shobhit Agrawal and Sophie Crux and Andrew W. Daman and Lena Wischhof and Miriam Stork and Margit Zweyer and Emma Dorotea Zanfi and Manon Chevallot-Beroux and Yunxiao Li and Elena De-Domenico and Dina Hüsson and Lorenzo Bonaguro and Yuanfang Li and Jonas Schulte-Schrepping and Qingyi Liang and Ketty Kessler and Dan Ehninger and Shahin Rafii and Jiankai Luo and Andreas Hermann and Annett Halle and Ying Liu and Elvira Mass and Melania Capasso and Hiroki Kato and Joachim L. Schultze and Pierluigi Nicotera and Daniele Bano and Steven Zvi Josefowicz and Martin Fuhrmann and Thomas Ulas and Marc Beyer and Juntang Lin and Monique M. B. Breteler and N. Ahmad Aziz and Paolo Salomoni},
  year = {2026},
  journal = {Nature Neuroscience},
  doi = {10.1038/s41593-026-02404-y},
  url = {https://doi.org/10.1038/s41593-026-02404-y}
}

RIS

TY  - JOUR
TI  - Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence
AU  - Xin Yan
AU  - Christina Georgopoulou
AU  - Hang-Mao Lee
AU  - Ala Ahrari
AU  - Jenny Russ
AU  - Vijay Chandrasekar
AU  - Tim Ducksch
AU  - Giuliano Crispatzu
AU  - Valentina Talevi
AU  - Liang Qiao
AU  - Shobhit Agrawal
AU  - Sophie Crux
AU  - Andrew W. Daman
AU  - Lena Wischhof
AU  - Miriam Stork
AU  - Margit Zweyer
AU  - Emma Dorotea Zanfi
AU  - Manon Chevallot-Beroux
AU  - Yunxiao Li
AU  - Elena De-Domenico
AU  - Dina Hüsson
AU  - Lorenzo Bonaguro
AU  - Yuanfang Li
AU  - Jonas Schulte-Schrepping
AU  - Qingyi Liang
AU  - Ketty Kessler
AU  - Dan Ehninger
AU  - Shahin Rafii
AU  - Jiankai Luo
AU  - Andreas Hermann
AU  - Annett Halle
AU  - Ying Liu
AU  - Elvira Mass
AU  - Melania Capasso
AU  - Hiroki Kato
AU  - Joachim L. Schultze
AU  - Pierluigi Nicotera
AU  - Daniele Bano
AU  - Steven Zvi Josefowicz
AU  - Martin Fuhrmann
AU  - Thomas Ulas
AU  - Marc Beyer
AU  - Juntang Lin
AU  - Monique M. B. Breteler
AU  - N. Ahmad Aziz
AU  - Paolo Salomoni
PY  - 2026
JO  - Nature Neuroscience
DO  - 10.1038/s41593-026-02404-y
UR  - https://doi.org/10.1038/s41593-026-02404-y
ER  -

APA

Yan, X., Georgopoulou, C., Lee, H., Ahrari, A., Russ, J., Chandrasekar, V., Ducksch, T., Crispatzu, G., Talevi, V., Qiao, L., Agrawal, S., Crux, S., Daman, A. W., Wischhof, L., Stork, M., Zweyer, M., Zanfi, E. D., Chevallot-Beroux, M., Li, Y., De-Domenico, E., Hüsson, D., Bonaguro, L., Li, Y., Schulte-Schrepping, J., Liang, Q., Kessler, K., Ehninger, D., Rafii, S., Luo, J., Hermann, A., Halle, A., Liu, Y., Mass, E., Capasso, M., Kato, H., Schultze, J. L., Nicotera, P., Bano, D., Josefowicz, S. Z., Fuhrmann, M., Ulas, T., Beyer, M., Lin, J., Breteler, M. M. B., Aziz, N. A., & Salomoni, P. (2026). Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence. Nature Neuroscience. https://doi.org/10.1038/s41593-026-02404-y

Source records

crossref · retrieved 2026-09-25T22:23:12.786Z