Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak, Vasilis Raptis, Yunye He, Tomoko Nakanishi, Erin Macdonald-Dunlop, Yoji Sagiya, Takayuki Morisaki, Koichi Matsuda, Unknown, Unknown, Ho Namkoong, Ryuya Edahiro, Tomomi Takano, Hiroshi Nishihara, Yuya Shirai, Kyuto Sonehara, Hiromu Tanaka, Shuhei Azekawa, Yohei Mikami, Ho Lee, Takanori Hasegawa, Koji Okudela, Daisuke Okuzaki, Daisuke Motooka, Masahiro Kanai, Tatsuhiko Naito, Kenichi Yamamoto, Qingbo S. Wang, Ryunosuke Saiki, Rino Ishihara, Yuta Matsubara, Junko Hamamoto, Hiroyuki Hayashi, Yukihiro Yoshimura, Natsuo Tachikawa, Emmy Yanagita, Takayoshi Hyugaji, Eigo Shimizu, Kotoe Katayama, Yasuhiro Kato, Takayoshi Morita, Kazuhisa Takahashi, Norihiro Harada, Toshio Naito, Makoto Hiki, Yasushi Matsushita, Haruhi Takagi, Ryousuke Aoki, Ai Nakamura, Sonoko Harada, Hitoshi Sasano, Hiroki Kabata, Katsunori Masaki, Hirofumi Kamata, Shinnosuke Ikemura, Shotaro Chubachi, Satoshi Okamori, Hideki Terai, Atsuho Morita, Takanori Asakura, Junichi Sasaki, Hiroshi Morisaki, Yoshifumi Uwamino, Kosaku Nanki, Sho Uchida, Shunsuke Uno, Tomoyasu Nishimura, Takashi Ishiguro, Taisuke Isono, Shun Shibata, Yuma Matsui, Chiaki Hosoda, Kenji Takano, Takashi Nishida, Yoichi Kobayashi, Yotaro Takaku, Noboru Takayanagi, Soichiro Ueda, Ai Tada, Masayoshi Miyawaki, Masaomi Yamamoto, Eriko Yoshida, Reina Hayashi, Tomoki Nagasaka, Sawako Arai, Yutaro Kaneko, Kana Sasaki, Etsuko Tagaya, Masatoshi Kawana, Ken Arimura, Kunihiko Takahashi, Tatsuhiko Anzai, Satoshi Ito, Akifumi Endo, Yuji Uchimura, Yasunari Miyazaki, Takayuki Honda, Tomoya Tateishi, Shuji Tohda, Naoya Ichimura, Kazunari Sonobe, Chihiro Tani Sassa, Jun Nakajima, Yasushi Nakano, Yukiko Nakajima, Ryusuke Anan, Ryosuke Arai, Yuko Kurihara, Yuko Harada, Kazumi Nishio, Tetsuya Ueda, Masanori Azuma, Ryuichi Saito, Toshikatsu Sado, Yoshimune Miyazaki, Ryuichi Sato, Yuki Haruta, Tadao Nagasaki, Yoshinori Yasui, Yoshinori Hasegawa, Yoshikazu Mutoh, Tomoki Kimura, Tomonori Sato, Reoto Takei, Satoshi Hagimoto, Yoichiro Noguchi, Yasuhiko Yamano, Hajime Sasano, Sho Ota, Yasushi Nakamori, Kazuhisa Yoshiya, Fukuki Saito, Tomoyuki Yoshihara, Daiki Wada, Hiromu Iwamura, Syuji Kanayama, Shuhei Maruyama, Takashi Yoshiyama, Ken Ohta, Hiroyuki Kokuto, Hideo Ogata, Yoshiaki Tanaka, Kenichi Arakawa, Masafumi Shimoda, Takeshi Osawa, Hiroki Tateno, Isano Hase, Shuichi Yoshida, Shoji Suzuki, Miki Kawada, Hirohisa Horinouchi, Fumitake Saito, Keiko Mitamura, Masao Hagihara, Junichi Ochi, Tomoyuki Uchida, Rie Baba, Daisuke Arai, Takayuki Ogura, Hidenori Takahashi, Shigehiro Hagiwara, Genta Nagao, Shunichiro Konishi, Ichiro Nakachi, Koji Murakami, Mitsuhiro Yamada, Hisatoshi Sugiura, Hirohito Sano, Shuichiro Matsumoto, Nozomu Kimura, Yoshinao Ono, Hiroaki Baba, Yusuke Suzuki, Sohei Nakayama, Keita Masuzawa, Shinichi Namba, Ken Suzuki, Yoko Naito, Yu-Chen Liu, Ayako Takuwa, Fuminori Sugihara, James B. Wing, Shuhei Sakakibara, Nobuyuki Hizawa, Takayuki Shiroyama, Satoru Miyawaki, Yusuke Kawamura, Akiyoshi Nakayama, Hirotaka Matsuo, Yuichi Maeda, Takuro Nii, Yoshimi Noda, Takayuki Niitsu, Yuichi Adachi, Takatoshi Enomoto, Saori Amiya, Reina Hara, Yuta Yamaguchi, Teruaki Murakami, Tomoki Kuge, Kinnosuke Matsumoto, Yuji Yamamoto, Makoto Yamamoto, Midori Yoneda, Toshihiro Kishikawa, Shuhei Yamada, Shuhei Kawabata, Noriyuki Kijima, Masatoshi Takagaki, Noah Sasa, Yuya Ueno, Motoyuki Suzuki, Norihiko Takemoto, Hirotaka Eguchi, Takahito Fukusumi, Takao Imai, Munehisa Fukushima, Haruhiko Kishima, Hidenori Inohara, Kazunori Tomono, Kazuto Kato, Meiko Takahashi, Fumihiko Matsuda, Haruhiko Hirata, Yoshito Takeda, Hidefumi Koh, Tadashi Manabe, Yohei Funatsu, Fumimaro Ito, Takahiro Fukui, Keisuke Shinozuka, Sumiko Kohashi, Masatoshi Miyazaki, Tomohisa Shoko, Mitsuaki Kojima, Tomohiro Adachi, Motonao Ishikawa, Kenichiro Takahashi, Takashi Inoue, Toshiyuki Hirano, Keigo Kobayashi, Hatsuyo Takaoka, Kazuyoshi Watanabe, Naoki Miyazawa, Yasuhiro Kimura, Reiko Sado, Hideyasu Sugimoto, Akane Kamiya, Naota Kuwahara, Akiko Fujiwara, Tomohiro Matsunaga, Yoko Sato, Takenori Okada, Yoshihiro Hirai, Hidetoshi Kawashima, Atsuya Narita, Kazuki Niwa, Yoshiyuki Sekikawa, Koichi Nishi, Masaru Nishitsuji, Mayuko Tani, Junya Suzuki, Hiroki Nakatsumi, Takashi Ogura, Hideya Kitamura, Eri Hagiwara, Kota Murohashi, Hiroko Okabayashi, Takao Mochimaru, Shigenari Nukaga, Ryosuke Satomi, Yoshitaka Oyamada, Nobuaki Mori, Tomoya Baba, Yasutaka Fukui, Mitsuru Odate, Shuko Mashimo, Yasushi Makino, Kazuma Yagi, Mizuha Hashiguchi, Junko Kagyo, Tetsuya Shiomi, Satoshi Fuke, Hiroshi Saito, Tomoya Tsuchida, Shigeki Fujitani, Mumon Takita, Daiki Morikawa, Toru Yoshida, Takehiro Izumo, Minoru Inomata, Naoyuki Kuse, Nobuyasu Awano, Mari Tone, Akihiro Ito, Yoshihiko Nakamura, Kota Hoshino, Junichi Maruyama, Hiroyasu Ishikura, Tohru Takata, Toshio Odani, Masaru Amishima, Takeshi Hattori, Yasuo Shichinohe, Takashi Kagaya, Toshiyuki Kita, Kazuhide Ohta, Satoru Sakagami, Kiyoshi Koshida, Kentaro Hayashi, Tetsuo Shimizu, Yutaka Kozu, Hisato Hiranuma, Yasuhiro Gon, Namiki Izumi, Kaoru Nagata, Ken Ueda, Reiko Taki, Satoko Hanada, Kodai Kawamura, Kazuya Ichikado, Kenta Nishiyama, Hiroyuki Muranaka, Kazunori Nakamura, Naozumi Hashimoto, Keiko Wakahara, Sakamoto Koji, Norihito Omote, Akira Ando, Nobuhiro Kodama, Yasunari Kaneyama, Shunsuke Maeda, Takashige Kuraki, Takemasa Matsumoto, Koutaro Yokote, Taka-Aki Nakada, Ryuzo Abe, Taku Oshima, Tadanaga Shimada, Masahiro Harada, Takeshi Takahashi, Hiroshi Ono, Toshihiro Sakurai, Takayuki Shibusawa, Yoshifumi Kimizuka, Akihiko Kawana, Tomoya Sano, Chie Watanabe, Ryohei Suematsu, Hisako Sageshima, Ayumi Yoshifuji, Kazuto Ito, Saeko Takahashi, Kota Ishioka, Morio Nakamura, Makoto Masuda, Aya Wakabayashi, Hiroki Watanabe, Suguru Ueda, Masanori Nishikawa, Yusuke Chihara, Mayumi Takeuchi, Keisuke Onoi, Jun Shinozuka, Atsushi Sueyoshi, Yoji Nagasaki, Masaki Okamoto, Sayoko Ishihara, Masatoshi Shimo, Yoshihisa Tokunaga, Yu Kusaka, Takehiko Ohba, Susumu Isogai, Aki Ogawa, Takuya Inoue, Satoru Fukuyama, Yoshihiro Eriguchi, Akiko Yonekawa, Keiko Kan-o, Koichiro Matsumoto, Kensuke Kanaoka, Shoichi Ihara, Kiyoshi Komuta, Yoshiaki Inoue, Shigeru Chiba, Kunihiro Yamagata, Yuji Hiramatsu, Hirayasu Kai, Koichiro Asano, Tsuyoshi Oguma, Yoko Ito, Satoru Hashimoto, Masaki Yamasaki, Yu Kasamatsu, Yuko Komase, Naoya Hida, Takahiro Tsuburai, Baku Oyama, Minoru Takada, Hidenori Kanda, Yuichiro Kitagawa, Tetsuya Fukuta, Takahito Miyake, Shozo Yoshida, Shinji Ogura, Shinji Abe, Yuta Kono, Yuki Togashi, Hiroyuki Takoi, Ryota Kikuchi, Shinichi Ogawa, Tomouki Ogata, Shoichiro Ishihara, Arihiko Kanehiro, Shinji Ozaki, Yasuko Fuchimoto, Sae Wada, Nobukazu Fujimoto, Kei Nishiyama, Mariko Terashima, Satoru Beppu, Kosuke Yoshida, Osamu Narumoto, Hideaki Nagai, Nobuharu Ooshima, Mitsuru Motegi, Akira Umeda, Kazuya Miyagawa, Hisato Shimada, Mayu Endo, Yoshiyuki Ohira, Masafumi Watanabe, Sumito Inoue, Akira Igarashi, Masamichi Sato, Hironori Sagara, Akihiko Tanaka, Shin Ohta, Tomoyuki Kimura, Yoko Shibata, Yoshinori Tanino, Takefumi Nikaido, Hiroyuki Minemura, Yuki Sato, Yuichiro Yamada, Takuya Hashino, Masato Shinoki, Hajime Iwagoe, Hiroshi Takahashi, Kazuhiko Fujii, Hiroto Kishi, Masayuki Kanai, Tomonori Imamura, Tatsuya Yamashita, Masakiyo Yatomi, Toshitaka Maeno, Shinichi Hayashi, Mai Takahashi, Mizuki Kuramochi, Isamu Kamimaki, Yoshiteru Tominaga, Tomoo Ishii, Mitsuyoshi Utsugi, Akihiro Ono, Toru Tanaka, Takeru Kashiwada, Kazue Fujita, Yoshinobu Saito, Masahiro Seike, Hiroko Watanabe, Hiroto Matsuse, Norio Kodaka, Chihiro Nakano, Takeshi Oshio, Takatomo Hirouchi, Shohei Makino, Moritoki Egi, Yosuke Omae, Yasuhito Nannya, Takafumi Ueno, Kazuhiko Katayama, Masumi Ai, Yoshinori Fukui, Atsushi Kumanogoh, Toshiro Sato, Naoki Hasegawa, Katsushi Tokunaga, Makoto Ishii, Ryuji Koike, Yuko Kitagawa, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada, Akinori Kanai, Yutaka Suzuki, Yoshiya Oda, Yoichiro Kamatani, Ho Namkoong, Ryunosuke Saiki, Akinori Kimura, Ryuji Koike, Seishi Ogawa, Satoru Miyano, Seiya Imoto, Takanori Kanai, Koichi Fukunaga, Yukinori Okada, Anders Mälarstig, Albert Tenesa

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DOI: 10.1038/s41598-025-10031-z
Published: 2025-08-28
Container: Scientific Reports
Publisher: Springer Science and Business Media LLC
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Cite this work

BibTeX

@article{allodium:10.1038/s41598-025-10031-z,
  title = {Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases},
  author = {Youngjune Bhak and Vasilis Raptis and Yunye He and Tomoko Nakanishi and Erin Macdonald-Dunlop and Yoji Sagiya and Takayuki Morisaki and Koichi Matsuda and Unknown and Unknown and Ho Namkoong and Ryuya Edahiro and Tomomi Takano and Hiroshi Nishihara and Yuya Shirai and Kyuto Sonehara and Hiromu Tanaka and Shuhei Azekawa and Yohei Mikami and Ho Lee and Takanori Hasegawa and Koji Okudela and Daisuke Okuzaki and Daisuke Motooka and Masahiro Kanai and Tatsuhiko Naito and Kenichi Yamamoto and Qingbo S. Wang and Ryunosuke Saiki and Rino Ishihara and Yuta Matsubara and Junko Hamamoto and Hiroyuki Hayashi and Yukihiro Yoshimura and Natsuo Tachikawa and Emmy Yanagita and Takayoshi Hyugaji and Eigo Shimizu and Kotoe Katayama and Yasuhiro Kato and Takayoshi Morita and Kazuhisa Takahashi and Norihiro Harada and Toshio Naito and Makoto Hiki and Yasushi Matsushita and Haruhi Takagi and Ryousuke Aoki and Ai Nakamura and Sonoko Harada and Hitoshi Sasano and Hiroki Kabata and Katsunori Masaki and Hirofumi Kamata and Shinnosuke Ikemura and Shotaro Chubachi and Satoshi Okamori and Hideki Terai and Atsuho Morita and Takanori Asakura and Junichi Sasaki and Hiroshi Morisaki and Yoshifumi Uwamino and Kosaku Nanki and Sho Uchida and Shunsuke Uno and Tomoyasu Nishimura and Takashi Ishiguro and Taisuke Isono and Shun Shibata and Yuma Matsui and Chiaki Hosoda and Kenji Takano and Takashi Nishida and Yoichi Kobayashi and Yotaro Takaku and Noboru Takayanagi and Soichiro Ueda and Ai Tada and Masayoshi Miyawaki and Masaomi Yamamoto and Eriko Yoshida and Reina Hayashi and Tomoki Nagasaka and Sawako Arai and Yutaro Kaneko and Kana Sasaki and Etsuko Tagaya and Masatoshi Kawana and Ken Arimura and Kunihiko Takahashi and Tatsuhiko Anzai and Satoshi Ito and Akifumi Endo and Yuji Uchimura and Yasunari Miyazaki and Takayuki Honda and Tomoya Tateishi and Shuji Tohda and Naoya Ichimura and Kazunari Sonobe and Chihiro Tani Sassa and Jun Nakajima and Yasushi Nakano and Yukiko Nakajima and Ryusuke Anan and Ryosuke Arai and Yuko Kurihara and Yuko Harada and Kazumi Nishio and Tetsuya Ueda and Masanori Azuma and Ryuichi Saito and Toshikatsu Sado and Yoshimune Miyazaki and Ryuichi Sato and Yuki Haruta and Tadao Nagasaki and Yoshinori Yasui and Yoshinori Hasegawa and Yoshikazu Mutoh and Tomoki Kimura and Tomonori Sato and Reoto Takei and Satoshi Hagimoto and Yoichiro Noguchi and Yasuhiko Yamano and Hajime Sasano and Sho Ota and Yasushi Nakamori and Kazuhisa Yoshiya and Fukuki Saito and Tomoyuki Yoshihara and Daiki Wada and Hiromu Iwamura and Syuji Kanayama and Shuhei Maruyama and Takashi Yoshiyama and Ken Ohta and Hiroyuki Kokuto and Hideo Ogata and Yoshiaki Tanaka and Kenichi Arakawa and Masafumi Shimoda and Takeshi Osawa and Hiroki Tateno and Isano Hase and Shuichi Yoshida and Shoji Suzuki and Miki Kawada and Hirohisa Horinouchi and Fumitake Saito and Keiko Mitamura and Masao Hagihara and Junichi Ochi and Tomoyuki Uchida and Rie Baba and Daisuke Arai and Takayuki Ogura and Hidenori Takahashi and Shigehiro Hagiwara and Genta Nagao and Shunichiro Konishi and Ichiro Nakachi and Koji Murakami and Mitsuhiro Yamada and Hisatoshi Sugiura and Hirohito Sano and Shuichiro Matsumoto and Nozomu Kimura and Yoshinao Ono and Hiroaki Baba and Yusuke Suzuki and Sohei Nakayama and Keita Masuzawa and Shinichi Namba and Ken Suzuki and Yoko Naito and Yu-Chen Liu and Ayako Takuwa and Fuminori Sugihara and James B. Wing and Shuhei Sakakibara and Nobuyuki Hizawa and Takayuki Shiroyama and Satoru Miyawaki and Yusuke Kawamura and Akiyoshi Nakayama and Hirotaka Matsuo and Yuichi Maeda and Takuro Nii and Yoshimi Noda and Takayuki Niitsu and Yuichi Adachi and Takatoshi Enomoto and Saori Amiya and Reina Hara and Yuta Yamaguchi and Teruaki Murakami and Tomoki Kuge and Kinnosuke Matsumoto and Yuji Yamamoto and Makoto Yamamoto and Midori Yoneda and Toshihiro Kishikawa and Shuhei Yamada and Shuhei Kawabata and Noriyuki Kijima and Masatoshi Takagaki and Noah Sasa and Yuya Ueno and Motoyuki Suzuki and Norihiko Takemoto and Hirotaka Eguchi and Takahito Fukusumi and Takao Imai and Munehisa Fukushima and Haruhiko Kishima and Hidenori Inohara and Kazunori Tomono and Kazuto Kato and Meiko Takahashi and Fumihiko Matsuda and Haruhiko Hirata and Yoshito Takeda and Hidefumi Koh and Tadashi Manabe and Yohei Funatsu and Fumimaro Ito and Takahiro Fukui and Keisuke Shinozuka and Sumiko Kohashi and Masatoshi Miyazaki and Tomohisa Shoko and Mitsuaki Kojima and Tomohiro Adachi and Motonao Ishikawa and Kenichiro Takahashi and Takashi Inoue and Toshiyuki Hirano and Keigo Kobayashi and Hatsuyo Takaoka and Kazuyoshi Watanabe and Naoki Miyazawa and Yasuhiro Kimura and Reiko Sado and Hideyasu Sugimoto and Akane Kamiya and Naota Kuwahara and Akiko Fujiwara and Tomohiro Matsunaga and Yoko Sato and Takenori Okada and Yoshihiro Hirai and Hidetoshi Kawashima and Atsuya Narita and Kazuki Niwa and Yoshiyuki Sekikawa and Koichi Nishi and Masaru Nishitsuji and Mayuko Tani and Junya Suzuki and Hiroki Nakatsumi and Takashi Ogura and Hideya Kitamura and Eri Hagiwara and Kota Murohashi and Hiroko Okabayashi and Takao Mochimaru and Shigenari Nukaga and Ryosuke Satomi and Yoshitaka Oyamada and Nobuaki Mori and Tomoya Baba and Yasutaka Fukui and Mitsuru Odate and Shuko Mashimo and Yasushi Makino and Kazuma Yagi and Mizuha Hashiguchi and Junko Kagyo and Tetsuya Shiomi and Satoshi Fuke and Hiroshi Saito and Tomoya Tsuchida and Shigeki Fujitani and Mumon Takita and Daiki Morikawa and Toru Yoshida and Takehiro Izumo and Minoru Inomata and Naoyuki Kuse and Nobuyasu Awano and Mari Tone and Akihiro Ito and Yoshihiko Nakamura and Kota Hoshino and Junichi Maruyama and Hiroyasu Ishikura and Tohru Takata and Toshio Odani and Masaru Amishima and Takeshi Hattori and Yasuo Shichinohe and Takashi Kagaya and Toshiyuki Kita and Kazuhide Ohta and Satoru Sakagami and Kiyoshi Koshida and Kentaro Hayashi and Tetsuo Shimizu and Yutaka Kozu and Hisato Hiranuma and Yasuhiro Gon and Namiki Izumi and Kaoru Nagata and Ken Ueda and Reiko Taki and Satoko Hanada and Kodai Kawamura and Kazuya Ichikado and Kenta Nishiyama and Hiroyuki Muranaka and Kazunori Nakamura and Naozumi Hashimoto and Keiko Wakahara and Sakamoto Koji and Norihito Omote and Akira Ando and Nobuhiro Kodama and Yasunari Kaneyama and Shunsuke Maeda and Takashige Kuraki and Takemasa Matsumoto and Koutaro Yokote and Taka-Aki Nakada and Ryuzo Abe and Taku Oshima and Tadanaga Shimada and Masahiro Harada and Takeshi Takahashi and Hiroshi Ono and Toshihiro Sakurai and Takayuki Shibusawa and Yoshifumi Kimizuka and Akihiko Kawana and Tomoya Sano and Chie Watanabe and Ryohei Suematsu and Hisako Sageshima and Ayumi Yoshifuji and Kazuto Ito and Saeko Takahashi and Kota Ishioka and Morio Nakamura and Makoto Masuda and Aya Wakabayashi and Hiroki Watanabe and Suguru Ueda and Masanori Nishikawa and Yusuke Chihara and Mayumi Takeuchi and Keisuke Onoi and Jun Shinozuka and Atsushi Sueyoshi and Yoji Nagasaki and Masaki Okamoto and Sayoko Ishihara and Masatoshi Shimo and Yoshihisa Tokunaga and Yu Kusaka and Takehiko Ohba and Susumu Isogai and Aki Ogawa and Takuya Inoue and Satoru Fukuyama and Yoshihiro Eriguchi and Akiko Yonekawa and Keiko Kan-o and Koichiro Matsumoto and Kensuke Kanaoka and Shoichi Ihara and Kiyoshi Komuta and Yoshiaki Inoue and Shigeru Chiba and Kunihiro Yamagata and Yuji Hiramatsu and Hirayasu Kai and Koichiro Asano and Tsuyoshi Oguma and Yoko Ito and Satoru Hashimoto and Masaki Yamasaki and Yu Kasamatsu and Yuko Komase and Naoya Hida and Takahiro Tsuburai and Baku Oyama and Minoru Takada and Hidenori Kanda and Yuichiro Kitagawa and Tetsuya Fukuta and Takahito Miyake and Shozo Yoshida and Shinji Ogura and Shinji Abe and Yuta Kono and Yuki Togashi and Hiroyuki Takoi and Ryota Kikuchi and Shinichi Ogawa and Tomouki Ogata and Shoichiro Ishihara and Arihiko Kanehiro and Shinji Ozaki and Yasuko Fuchimoto and Sae Wada and Nobukazu Fujimoto and Kei Nishiyama and Mariko Terashima and Satoru Beppu and Kosuke Yoshida and Osamu Narumoto and Hideaki Nagai and Nobuharu Ooshima and Mitsuru Motegi and Akira Umeda and Kazuya Miyagawa and Hisato Shimada and Mayu Endo and Yoshiyuki Ohira and Masafumi Watanabe and Sumito Inoue and Akira Igarashi and Masamichi Sato and Hironori Sagara and Akihiko Tanaka and Shin Ohta and Tomoyuki Kimura and Yoko Shibata and Yoshinori Tanino and Takefumi Nikaido and Hiroyuki Minemura and Yuki Sato and Yuichiro Yamada and Takuya Hashino and Masato Shinoki and Hajime Iwagoe and Hiroshi Takahashi and Kazuhiko Fujii and Hiroto Kishi and Masayuki Kanai and Tomonori Imamura and Tatsuya Yamashita and Masakiyo Yatomi and Toshitaka Maeno and Shinichi Hayashi and Mai Takahashi and Mizuki Kuramochi and Isamu Kamimaki and Yoshiteru Tominaga and Tomoo Ishii and Mitsuyoshi Utsugi and Akihiro Ono and Toru Tanaka and Takeru Kashiwada and Kazue Fujita and Yoshinobu Saito and Masahiro Seike and Hiroko Watanabe and Hiroto Matsuse and Norio Kodaka and Chihiro Nakano and Takeshi Oshio and Takatomo Hirouchi and Shohei Makino and Moritoki Egi and Yosuke Omae and Yasuhito Nannya and Takafumi Ueno and Kazuhiko Katayama and Masumi Ai and Yoshinori Fukui and Atsushi Kumanogoh and Toshiro Sato and Naoki Hasegawa and Katsushi Tokunaga and Makoto Ishii and Ryuji Koike and Yuko Kitagawa and Akinori Kimura and Seiya Imoto and Satoru Miyano and Seishi Ogawa and Takanori Kanai and Koichi Fukunaga and Yukinori Okada and Akinori Kanai and Yutaka Suzuki and Yoshiya Oda and Yoichiro Kamatani and Ho Namkoong and Ryunosuke Saiki and Akinori Kimura and Ryuji Koike and Seishi Ogawa and Satoru Miyano and Seiya Imoto and Takanori Kanai and Koichi Fukunaga and Yukinori Okada and Anders Mälarstig and Albert Tenesa},
  year = {2025},
  journal = {Scientific Reports},
  doi = {10.1038/s41598-025-10031-z},
  url = {https://doi.org/10.1038/s41598-025-10031-z}
}

RIS

TY  - JOUR
TI  - Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases
AU  - Youngjune Bhak
AU  - Vasilis Raptis
AU  - Yunye He
AU  - Tomoko Nakanishi
AU  - Erin Macdonald-Dunlop
AU  - Yoji Sagiya
AU  - Takayuki Morisaki
AU  - Koichi Matsuda
AU  - Unknown
AU  - Unknown
AU  - Ho Namkoong
AU  - Ryuya Edahiro
AU  - Tomomi Takano
AU  - Hiroshi Nishihara
AU  - Yuya Shirai
AU  - Kyuto Sonehara
AU  - Hiromu Tanaka
AU  - Shuhei Azekawa
AU  - Yohei Mikami
AU  - Ho Lee
AU  - Takanori Hasegawa
AU  - Koji Okudela
AU  - Daisuke Okuzaki
AU  - Daisuke Motooka
AU  - Masahiro Kanai
AU  - Tatsuhiko Naito
AU  - Kenichi Yamamoto
AU  - Qingbo S. Wang
AU  - Ryunosuke Saiki
AU  - Rino Ishihara
AU  - Yuta Matsubara
AU  - Junko Hamamoto
AU  - Hiroyuki Hayashi
AU  - Yukihiro Yoshimura
AU  - Natsuo Tachikawa
AU  - Emmy Yanagita
AU  - Takayoshi Hyugaji
AU  - Eigo Shimizu
AU  - Kotoe Katayama
AU  - Yasuhiro Kato
AU  - Takayoshi Morita
AU  - Kazuhisa Takahashi
AU  - Norihiro Harada
AU  - Toshio Naito
AU  - Makoto Hiki
AU  - Yasushi Matsushita
AU  - Haruhi Takagi
AU  - Ryousuke Aoki
AU  - Ai Nakamura
AU  - Sonoko Harada
AU  - Hitoshi Sasano
AU  - Hiroki Kabata
AU  - Katsunori Masaki
AU  - Hirofumi Kamata
AU  - Shinnosuke Ikemura
AU  - Shotaro Chubachi
AU  - Satoshi Okamori
AU  - Hideki Terai
AU  - Atsuho Morita
AU  - Takanori Asakura
AU  - Junichi Sasaki
AU  - Hiroshi Morisaki
AU  - Yoshifumi Uwamino
AU  - Kosaku Nanki
AU  - Sho Uchida
AU  - Shunsuke Uno
AU  - Tomoyasu Nishimura
AU  - Takashi Ishiguro
AU  - Taisuke Isono
AU  - Shun Shibata
AU  - Yuma Matsui
AU  - Chiaki Hosoda
AU  - Kenji Takano
AU  - Takashi Nishida
AU  - Yoichi Kobayashi
AU  - Yotaro Takaku
AU  - Noboru Takayanagi
AU  - Soichiro Ueda
AU  - Ai Tada
AU  - Masayoshi Miyawaki
AU  - Masaomi Yamamoto
AU  - Eriko Yoshida
AU  - Reina Hayashi
AU  - Tomoki Nagasaka
AU  - Sawako Arai
AU  - Yutaro Kaneko
AU  - Kana Sasaki
AU  - Etsuko Tagaya
AU  - Masatoshi Kawana
AU  - Ken Arimura
AU  - Kunihiko Takahashi
AU  - Tatsuhiko Anzai
AU  - Satoshi Ito
AU  - Akifumi Endo
AU  - Yuji Uchimura
AU  - Yasunari Miyazaki
AU  - Takayuki Honda
AU  - Tomoya Tateishi
AU  - Shuji Tohda
AU  - Naoya Ichimura
AU  - Kazunari Sonobe
AU  - Chihiro Tani Sassa
AU  - Jun Nakajima
AU  - Yasushi Nakano
AU  - Yukiko Nakajima
AU  - Ryusuke Anan
AU  - Ryosuke Arai
AU  - Yuko Kurihara
AU  - Yuko Harada
AU  - Kazumi Nishio
AU  - Tetsuya Ueda
AU  - Masanori Azuma
AU  - Ryuichi Saito
AU  - Toshikatsu Sado
AU  - Yoshimune Miyazaki
AU  - Ryuichi Sato
AU  - Yuki Haruta
AU  - Tadao Nagasaki
AU  - Yoshinori Yasui
AU  - Yoshinori Hasegawa
AU  - Yoshikazu Mutoh
AU  - Tomoki Kimura
AU  - Tomonori Sato
AU  - Reoto Takei
AU  - Satoshi Hagimoto
AU  - Yoichiro Noguchi
AU  - Yasuhiko Yamano
AU  - Hajime Sasano
AU  - Sho Ota
AU  - Yasushi Nakamori
AU  - Kazuhisa Yoshiya
AU  - Fukuki Saito
AU  - Tomoyuki Yoshihara
AU  - Daiki Wada
AU  - Hiromu Iwamura
AU  - Syuji Kanayama
AU  - Shuhei Maruyama
AU  - Takashi Yoshiyama
AU  - Ken Ohta
AU  - Hiroyuki Kokuto
AU  - Hideo Ogata
AU  - Yoshiaki Tanaka
AU  - Kenichi Arakawa
AU  - Masafumi Shimoda
AU  - Takeshi Osawa
AU  - Hiroki Tateno
AU  - Isano Hase
AU  - Shuichi Yoshida
AU  - Shoji Suzuki
AU  - Miki Kawada
AU  - Hirohisa Horinouchi
AU  - Fumitake Saito
AU  - Keiko Mitamura
AU  - Masao Hagihara
AU  - Junichi Ochi
AU  - Tomoyuki Uchida
AU  - Rie Baba
AU  - Daisuke Arai
AU  - Takayuki Ogura
AU  - Hidenori Takahashi
AU  - Shigehiro Hagiwara
AU  - Genta Nagao
AU  - Shunichiro Konishi
AU  - Ichiro Nakachi
AU  - Koji Murakami
AU  - Mitsuhiro Yamada
AU  - Hisatoshi Sugiura
AU  - Hirohito Sano
AU  - Shuichiro Matsumoto
AU  - Nozomu Kimura
AU  - Yoshinao Ono
AU  - Hiroaki Baba
AU  - Yusuke Suzuki
AU  - Sohei Nakayama
AU  - Keita Masuzawa
AU  - Shinichi Namba
AU  - Ken Suzuki
AU  - Yoko Naito
AU  - Yu-Chen Liu
AU  - Ayako Takuwa
AU  - Fuminori Sugihara
AU  - James B. Wing
AU  - Shuhei Sakakibara
AU  - Nobuyuki Hizawa
AU  - Takayuki Shiroyama
AU  - Satoru Miyawaki
AU  - Yusuke Kawamura
AU  - Akiyoshi Nakayama
AU  - Hirotaka Matsuo
AU  - Yuichi Maeda
AU  - Takuro Nii
AU  - Yoshimi Noda
AU  - Takayuki Niitsu
AU  - Yuichi Adachi
AU  - Takatoshi Enomoto
AU  - Saori Amiya
AU  - Reina Hara
AU  - Yuta Yamaguchi
AU  - Teruaki Murakami
AU  - Tomoki Kuge
AU  - Kinnosuke Matsumoto
AU  - Yuji Yamamoto
AU  - Makoto Yamamoto
AU  - Midori Yoneda
AU  - Toshihiro Kishikawa
AU  - Shuhei Yamada
AU  - Shuhei Kawabata
AU  - Noriyuki Kijima
AU  - Masatoshi Takagaki
AU  - Noah Sasa
AU  - Yuya Ueno
AU  - Motoyuki Suzuki
AU  - Norihiko Takemoto
AU  - Hirotaka Eguchi
AU  - Takahito Fukusumi
AU  - Takao Imai
AU  - Munehisa Fukushima
AU  - Haruhiko Kishima
AU  - Hidenori Inohara
AU  - Kazunori Tomono
AU  - Kazuto Kato
AU  - Meiko Takahashi
AU  - Fumihiko Matsuda
AU  - Haruhiko Hirata
AU  - Yoshito Takeda
AU  - Hidefumi Koh
AU  - Tadashi Manabe
AU  - Yohei Funatsu
AU  - Fumimaro Ito
AU  - Takahiro Fukui
AU  - Keisuke Shinozuka
AU  - Sumiko Kohashi
AU  - Masatoshi Miyazaki
AU  - Tomohisa Shoko
AU  - Mitsuaki Kojima
AU  - Tomohiro Adachi
AU  - Motonao Ishikawa
AU  - Kenichiro Takahashi
AU  - Takashi Inoue
AU  - Toshiyuki Hirano
AU  - Keigo Kobayashi
AU  - Hatsuyo Takaoka
AU  - Kazuyoshi Watanabe
AU  - Naoki Miyazawa
AU  - Yasuhiro Kimura
AU  - Reiko Sado
AU  - Hideyasu Sugimoto
AU  - Akane Kamiya
AU  - Naota Kuwahara
AU  - Akiko Fujiwara
AU  - Tomohiro Matsunaga
AU  - Yoko Sato
AU  - Takenori Okada
AU  - Yoshihiro Hirai
AU  - Hidetoshi Kawashima
AU  - Atsuya Narita
AU  - Kazuki Niwa
AU  - Yoshiyuki Sekikawa
AU  - Koichi Nishi
AU  - Masaru Nishitsuji
AU  - Mayuko Tani
AU  - Junya Suzuki
AU  - Hiroki Nakatsumi
AU  - Takashi Ogura
AU  - Hideya Kitamura
AU  - Eri Hagiwara
AU  - Kota Murohashi
AU  - Hiroko Okabayashi
AU  - Takao Mochimaru
AU  - Shigenari Nukaga
AU  - Ryosuke Satomi
AU  - Yoshitaka Oyamada
AU  - Nobuaki Mori
AU  - Tomoya Baba
AU  - Yasutaka Fukui
AU  - Mitsuru Odate
AU  - Shuko Mashimo
AU  - Yasushi Makino
AU  - Kazuma Yagi
AU  - Mizuha Hashiguchi
AU  - Junko Kagyo
AU  - Tetsuya Shiomi
AU  - Satoshi Fuke
AU  - Hiroshi Saito
AU  - Tomoya Tsuchida
AU  - Shigeki Fujitani
AU  - Mumon Takita
AU  - Daiki Morikawa
AU  - Toru Yoshida
AU  - Takehiro Izumo
AU  - Minoru Inomata
AU  - Naoyuki Kuse
AU  - Nobuyasu Awano
AU  - Mari Tone
AU  - Akihiro Ito
AU  - Yoshihiko Nakamura
AU  - Kota Hoshino
AU  - Junichi Maruyama
AU  - Hiroyasu Ishikura
AU  - Tohru Takata
AU  - Toshio Odani
AU  - Masaru Amishima
AU  - Takeshi Hattori
AU  - Yasuo Shichinohe
AU  - Takashi Kagaya
AU  - Toshiyuki Kita
AU  - Kazuhide Ohta
AU  - Satoru Sakagami
AU  - Kiyoshi Koshida
AU  - Kentaro Hayashi
AU  - Tetsuo Shimizu
AU  - Yutaka Kozu
AU  - Hisato Hiranuma
AU  - Yasuhiro Gon
AU  - Namiki Izumi
AU  - Kaoru Nagata
AU  - Ken Ueda
AU  - Reiko Taki
AU  - Satoko Hanada
AU  - Kodai Kawamura
AU  - Kazuya Ichikado
AU  - Kenta Nishiyama
AU  - Hiroyuki Muranaka
AU  - Kazunori Nakamura
AU  - Naozumi Hashimoto
AU  - Keiko Wakahara
AU  - Sakamoto Koji
AU  - Norihito Omote
AU  - Akira Ando
AU  - Nobuhiro Kodama
AU  - Yasunari Kaneyama
AU  - Shunsuke Maeda
AU  - Takashige Kuraki
AU  - Takemasa Matsumoto
AU  - Koutaro Yokote
AU  - Taka-Aki Nakada
AU  - Ryuzo Abe
AU  - Taku Oshima
AU  - Tadanaga Shimada
AU  - Masahiro Harada
AU  - Takeshi Takahashi
AU  - Hiroshi Ono
AU  - Toshihiro Sakurai
AU  - Takayuki Shibusawa
AU  - Yoshifumi Kimizuka
AU  - Akihiko Kawana
AU  - Tomoya Sano
AU  - Chie Watanabe
AU  - Ryohei Suematsu
AU  - Hisako Sageshima
AU  - Ayumi Yoshifuji
AU  - Kazuto Ito
AU  - Saeko Takahashi
AU  - Kota Ishioka
AU  - Morio Nakamura
AU  - Makoto Masuda
AU  - Aya Wakabayashi
AU  - Hiroki Watanabe
AU  - Suguru Ueda
AU  - Masanori Nishikawa
AU  - Yusuke Chihara
AU  - Mayumi Takeuchi
AU  - Keisuke Onoi
AU  - Jun Shinozuka
AU  - Atsushi Sueyoshi
AU  - Yoji Nagasaki
AU  - Masaki Okamoto
AU  - Sayoko Ishihara
AU  - Masatoshi Shimo
AU  - Yoshihisa Tokunaga
AU  - Yu Kusaka
AU  - Takehiko Ohba
AU  - Susumu Isogai
AU  - Aki Ogawa
AU  - Takuya Inoue
AU  - Satoru Fukuyama
AU  - Yoshihiro Eriguchi
AU  - Akiko Yonekawa
AU  - Keiko Kan-o
AU  - Koichiro Matsumoto
AU  - Kensuke Kanaoka
AU  - Shoichi Ihara
AU  - Kiyoshi Komuta
AU  - Yoshiaki Inoue
AU  - Shigeru Chiba
AU  - Kunihiro Yamagata
AU  - Yuji Hiramatsu
AU  - Hirayasu Kai
AU  - Koichiro Asano
AU  - Tsuyoshi Oguma
AU  - Yoko Ito
AU  - Satoru Hashimoto
AU  - Masaki Yamasaki
AU  - Yu Kasamatsu
AU  - Yuko Komase
AU  - Naoya Hida
AU  - Takahiro Tsuburai
AU  - Baku Oyama
AU  - Minoru Takada
AU  - Hidenori Kanda
AU  - Yuichiro Kitagawa
AU  - Tetsuya Fukuta
AU  - Takahito Miyake
AU  - Shozo Yoshida
AU  - Shinji Ogura
AU  - Shinji Abe
AU  - Yuta Kono
AU  - Yuki Togashi
AU  - Hiroyuki Takoi
AU  - Ryota Kikuchi
AU  - Shinichi Ogawa
AU  - Tomouki Ogata
AU  - Shoichiro Ishihara
AU  - Arihiko Kanehiro
AU  - Shinji Ozaki
AU  - Yasuko Fuchimoto
AU  - Sae Wada
AU  - Nobukazu Fujimoto
AU  - Kei Nishiyama
AU  - Mariko Terashima
AU  - Satoru Beppu
AU  - Kosuke Yoshida
AU  - Osamu Narumoto
AU  - Hideaki Nagai
AU  - Nobuharu Ooshima
AU  - Mitsuru Motegi
AU  - Akira Umeda
AU  - Kazuya Miyagawa
AU  - Hisato Shimada
AU  - Mayu Endo
AU  - Yoshiyuki Ohira
AU  - Masafumi Watanabe
AU  - Sumito Inoue
AU  - Akira Igarashi
AU  - Masamichi Sato
AU  - Hironori Sagara
AU  - Akihiko Tanaka
AU  - Shin Ohta
AU  - Tomoyuki Kimura
AU  - Yoko Shibata
AU  - Yoshinori Tanino
AU  - Takefumi Nikaido
AU  - Hiroyuki Minemura
AU  - Yuki Sato
AU  - Yuichiro Yamada
AU  - Takuya Hashino
AU  - Masato Shinoki
AU  - Hajime Iwagoe
AU  - Hiroshi Takahashi
AU  - Kazuhiko Fujii
AU  - Hiroto Kishi
AU  - Masayuki Kanai
AU  - Tomonori Imamura
AU  - Tatsuya Yamashita
AU  - Masakiyo Yatomi
AU  - Toshitaka Maeno
AU  - Shinichi Hayashi
AU  - Mai Takahashi
AU  - Mizuki Kuramochi
AU  - Isamu Kamimaki
AU  - Yoshiteru Tominaga
AU  - Tomoo Ishii
AU  - Mitsuyoshi Utsugi
AU  - Akihiro Ono
AU  - Toru Tanaka
AU  - Takeru Kashiwada
AU  - Kazue Fujita
AU  - Yoshinobu Saito
AU  - Masahiro Seike
AU  - Hiroko Watanabe
AU  - Hiroto Matsuse
AU  - Norio Kodaka
AU  - Chihiro Nakano
AU  - Takeshi Oshio
AU  - Takatomo Hirouchi
AU  - Shohei Makino
AU  - Moritoki Egi
AU  - Yosuke Omae
AU  - Yasuhito Nannya
AU  - Takafumi Ueno
AU  - Kazuhiko Katayama
AU  - Masumi Ai
AU  - Yoshinori Fukui
AU  - Atsushi Kumanogoh
AU  - Toshiro Sato
AU  - Naoki Hasegawa
AU  - Katsushi Tokunaga
AU  - Makoto Ishii
AU  - Ryuji Koike
AU  - Yuko Kitagawa
AU  - Akinori Kimura
AU  - Seiya Imoto
AU  - Satoru Miyano
AU  - Seishi Ogawa
AU  - Takanori Kanai
AU  - Koichi Fukunaga
AU  - Yukinori Okada
AU  - Akinori Kanai
AU  - Yutaka Suzuki
AU  - Yoshiya Oda
AU  - Yoichiro Kamatani
AU  - Ho Namkoong
AU  - Ryunosuke Saiki
AU  - Akinori Kimura
AU  - Ryuji Koike
AU  - Seishi Ogawa
AU  - Satoru Miyano
AU  - Seiya Imoto
AU  - Takanori Kanai
AU  - Koichi Fukunaga
AU  - Yukinori Okada
AU  - Anders Mälarstig
AU  - Albert Tenesa
PY  - 2025
JO  - Scientific Reports
DO  - 10.1038/s41598-025-10031-z
UR  - https://doi.org/10.1038/s41598-025-10031-z
ER  -

APA

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(2025). Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases. Scientific Reports. https://doi.org/10.1038/s41598-025-10031-z

Source records

crossref · retrieved 2026-09-26T08:56:34.565Z