Microsecond simulations to investigate the structural mechanism of super-resistant double mutations in BTK to the covalent inhibitor ibrutinib in multiple leukemia

Abbas Khan, Syed Shujait Ali, Muhammad Ammar Zahid, Fahad M. Alshabrmi, Raed M. Al-Zoubi, Mohanad Shkoor, Anwar Mohammmad, Dong-Qing Wei, Abdelali Agouni

Open source

DOI
10.1038/s41598-025-24745-7
Published
2025-11-20
Container
Scientific Reports
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s41598-025-24745-7,
  title = {Microsecond simulations to investigate the structural mechanism of super-resistant double mutations in BTK to the covalent inhibitor ibrutinib in multiple leukemia},
  author = {Abbas Khan and Syed Shujait Ali and Muhammad Ammar Zahid and Fahad M. Alshabrmi and Raed M. Al-Zoubi and Mohanad Shkoor and Anwar Mohammmad and Dong-Qing Wei and Abdelali Agouni},
  year = {2025},
  journal = {Scientific Reports},
  doi = {10.1038/s41598-025-24745-7},
  url = {https://doi.org/10.1038/s41598-025-24745-7}
}

RIS

TY  - JOUR
TI  - Microsecond simulations to investigate the structural mechanism of super-resistant double mutations in BTK to the covalent inhibitor ibrutinib in multiple leukemia
AU  - Abbas Khan
AU  - Syed Shujait Ali
AU  - Muhammad Ammar Zahid
AU  - Fahad M. Alshabrmi
AU  - Raed M. Al-Zoubi
AU  - Mohanad Shkoor
AU  - Anwar Mohammmad
AU  - Dong-Qing Wei
AU  - Abdelali Agouni
PY  - 2025
JO  - Scientific Reports
DO  - 10.1038/s41598-025-24745-7
UR  - https://doi.org/10.1038/s41598-025-24745-7
ER  - 

APA

Khan, A., Ali, S. S., Zahid, M. A., Alshabrmi, F. M., Al-Zoubi, R. M., Shkoor, M., Mohammmad, A., Wei, D., & Agouni, A. (2025). Microsecond simulations to investigate the structural mechanism of super-resistant double mutations in BTK to the covalent inhibitor ibrutinib in multiple leukemia. Scientific Reports. https://doi.org/10.1038/s41598-025-24745-7

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