PI3K gene variants are associated with elevated IL-6 levels and COVID-19 severe outcomes in a multicenter study

Bruna Ramos Tosta, João Victor Andrade Cruz, Ingrid Marins de Almeida, Laryssa Cardoso Calmon, Laiane da Cruz Pena, Hatilla dos Santos Silva, Dyjaene de Oliveira Barbosa, Isa Rita Brito de Morais, Fabiane S. Reis-Goes, Nívia N. Silva, Gabriella Oliveira, Sara Nunes Vaz, Iris Montaño-Castellón, Daniele Santana, Ricardo Gassmann Figueiredo, Fabyan Esberard de Lima Beltrão, Valdirene Leão Carneiro, Gubio Soares Campos, Carlos Brites, Vitor Fortuna, Alex José Leite Torres, Camila Alexandrina Figueiredo, Soraya Castro Trindade, Helton Estrela Ramos, Ryan dos Santos Costa

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DOI: 10.1038/s41598-026-57773-y
Published: 2026-07-17
Container: Scientific Reports
Publisher: Springer Science and Business Media LLC
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1038/s41598-026-57773-y,
  title = {PI3K gene variants are associated with elevated IL-6 levels and COVID-19 severe outcomes in a multicenter study},
  author = {Bruna Ramos Tosta and João Victor Andrade Cruz and Ingrid Marins de Almeida and Laryssa Cardoso Calmon and Laiane da Cruz Pena and Hatilla dos Santos Silva and Dyjaene de Oliveira Barbosa and Isa Rita Brito de Morais and Fabiane S. Reis-Goes and Nívia N. Silva and Gabriella Oliveira and Sara Nunes Vaz and Iris Montaño-Castellón and Daniele Santana and Ricardo Gassmann Figueiredo and Fabyan Esberard de Lima Beltrão and Valdirene Leão Carneiro and Gubio Soares Campos and Carlos Brites and Vitor Fortuna and Alex José Leite Torres and Camila Alexandrina Figueiredo and Soraya Castro Trindade and Helton Estrela Ramos and Ryan dos Santos Costa},
  year = {2026},
  journal = {Scientific Reports},
  doi = {10.1038/s41598-026-57773-y},
  url = {https://doi.org/10.1038/s41598-026-57773-y}
}

RIS

TY  - JOUR
TI  - PI3K gene variants are associated with elevated IL-6 levels and COVID-19 severe outcomes in a multicenter study
AU  - Bruna Ramos Tosta
AU  - João Victor Andrade Cruz
AU  - Ingrid Marins de Almeida
AU  - Laryssa Cardoso Calmon
AU  - Laiane da Cruz Pena
AU  - Hatilla dos Santos Silva
AU  - Dyjaene de Oliveira Barbosa
AU  - Isa Rita Brito de Morais
AU  - Fabiane S. Reis-Goes
AU  - Nívia N. Silva
AU  - Gabriella Oliveira
AU  - Sara Nunes Vaz
AU  - Iris Montaño-Castellón
AU  - Daniele Santana
AU  - Ricardo Gassmann Figueiredo
AU  - Fabyan Esberard de Lima Beltrão
AU  - Valdirene Leão Carneiro
AU  - Gubio Soares Campos
AU  - Carlos Brites
AU  - Vitor Fortuna
AU  - Alex José Leite Torres
AU  - Camila Alexandrina Figueiredo
AU  - Soraya Castro Trindade
AU  - Helton Estrela Ramos
AU  - Ryan dos Santos Costa
PY  - 2026
JO  - Scientific Reports
DO  - 10.1038/s41598-026-57773-y
UR  - https://doi.org/10.1038/s41598-026-57773-y
ER  -

APA

Tosta, B. R., Cruz, J. V. A., Almeida, I. M. D., Calmon, L. C., Pena, L. D. C., Silva, H. D. S., Barbosa, D. D. O., Morais, I. R. B. D., Reis-Goes, F. S., Silva, N. N., Oliveira, G., Vaz, S. N., Montaño-Castellón, I., Santana, D., Figueiredo, R. G., Beltrão, F. E. D. L., Carneiro, V. L., Campos, G. S., Brites, C., Fortuna, V., Torres, A. J. L., Figueiredo, C. A., Trindade, S. C., Ramos, H. E., & Costa, R. D. S. (2026). PI3K gene variants are associated with elevated IL-6 levels and COVID-19 severe outcomes in a multicenter study. Scientific Reports. https://doi.org/10.1038/s41598-026-57773-y

Source records

crossref · retrieved 2026-09-26T09:52:01.845Z