Targeting NLRP3 with GDC-2394 ameliorates airway inflammation and smooth muscle hyperplasia in experimental asthma by suppressing the IL-6/JAK2/STAT3 axis

Zhiyuan Wang, Zhenzhen Guo, Yanan Wang, Qianqian Dai, Muhammad Imran Arif, Aizetiguli Maiming, Menghua Li, Aliya Maimaitiniyazi, Xueli Wang, Jianjiang Cui, Shengmeng Qu, Wen Zhao, Liang Ru

Open source

DOI
10.1038/s41598-026-63715-5
Published
2026-07-27
Container
Scientific Reports
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s41598-026-63715-5,
  title = {Targeting NLRP3 with GDC-2394 ameliorates airway inflammation and smooth muscle hyperplasia in experimental asthma by suppressing the IL-6/JAK2/STAT3 axis},
  author = {Zhiyuan Wang and Zhenzhen Guo and Yanan Wang and Qianqian Dai and Muhammad Imran Arif and Aizetiguli Maiming and Menghua Li and Aliya Maimaitiniyazi and Xueli Wang and Jianjiang Cui and Shengmeng Qu and Wen Zhao and Liang Ru},
  year = {2026},
  journal = {Scientific Reports},
  doi = {10.1038/s41598-026-63715-5},
  url = {https://doi.org/10.1038/s41598-026-63715-5}
}

RIS

TY  - JOUR
TI  - Targeting NLRP3 with GDC-2394 ameliorates airway inflammation and smooth muscle hyperplasia in experimental asthma by suppressing the IL-6/JAK2/STAT3 axis
AU  - Zhiyuan Wang
AU  - Zhenzhen Guo
AU  - Yanan Wang
AU  - Qianqian Dai
AU  - Muhammad Imran Arif
AU  - Aizetiguli Maiming
AU  - Menghua Li
AU  - Aliya Maimaitiniyazi
AU  - Xueli Wang
AU  - Jianjiang Cui
AU  - Shengmeng Qu
AU  - Wen Zhao
AU  - Liang Ru
PY  - 2026
JO  - Scientific Reports
DO  - 10.1038/s41598-026-63715-5
UR  - https://doi.org/10.1038/s41598-026-63715-5
ER  - 

APA

Wang, Z., Guo, Z., Wang, Y., Dai, Q., Arif, M. I., Maiming, A., Li, M., Maimaitiniyazi, A., Wang, X., Cui, J., Qu, S., Zhao, W., & Ru, L. (2026). Targeting NLRP3 with GDC-2394 ameliorates airway inflammation and smooth muscle hyperplasia in experimental asthma by suppressing the IL-6/JAK2/STAT3 axis. Scientific Reports. https://doi.org/10.1038/s41598-026-63715-5

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