Discovery of a pyrazolopyridine alkaloid that mitigates neuronal ER stress and age-related decline.

Jantrapirom S, Sangphukieo A, U-On N, Poonsawas P, Wongkumool W, Yeewa R, Panto C, Poound P, Zito E, Marrazza A, Lo Piccolo L

Open source

DOI: 10.1038/s42003-026-10226-8
Published: 2026 May 8
Container: Communications biology
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s42003-026-10226-8,
  title = {Discovery of a pyrazolopyridine alkaloid that mitigates neuronal ER stress and age-related decline.},
  author = {Jantrapirom S and Sangphukieo A and U-On N and Poonsawas P and Wongkumool W and Yeewa R and Panto C and Poound P and Zito E and Marrazza A and Lo Piccolo L},
  year = {2026},
  journal = {Communications biology},
  doi = {10.1038/s42003-026-10226-8},
  url = {https://doi.org/10.1038/s42003-026-10226-8}
}

RIS

TY  - JOUR
TI  - Discovery of a pyrazolopyridine alkaloid that mitigates neuronal ER stress and age-related decline.
AU  - Jantrapirom S
AU  - Sangphukieo A
AU  - U-On N
AU  - Poonsawas P
AU  - Wongkumool W
AU  - Yeewa R
AU  - Panto C
AU  - Poound P
AU  - Zito E
AU  - Marrazza A
AU  - Lo Piccolo L
PY  - 2026
JO  - Communications biology
DO  - 10.1038/s42003-026-10226-8
UR  - https://doi.org/10.1038/s42003-026-10226-8
ER  -

APA

S, J., A, S., N, U., P, P., W, W., R, Y., C, P., P, P., E, Z., A, M., & L, L. P. (2026). Discovery of a pyrazolopyridine alkaloid that mitigates neuronal ER stress and age-related decline.. Communications biology. https://doi.org/10.1038/s42003-026-10226-8

Source records

pubmed · retrieved 2026-09-25T12:33:41.496Z