Succinate dehydrogenase loss suppresses pyrimidine biosynthesis via succinate-mediated inhibition of aspartate transcarbamylase

Madeleine L. Hart, David Sokolov, Serwah Danquah, Eric Zheng, Alex D. Doan, Kristian Davidsen, David MacPherson, Lucas B. Sullivan

Open source

DOI
10.1038/s42255-026-01524-w
Published
2026-05-04
Container
Nature Metabolism
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s42255-026-01524-w,
  title = {Succinate dehydrogenase loss suppresses pyrimidine biosynthesis via succinate-mediated inhibition of aspartate transcarbamylase},
  author = {Madeleine L. Hart and David Sokolov and Serwah Danquah and Eric Zheng and Alex D. Doan and Kristian Davidsen and David MacPherson and Lucas B. Sullivan},
  year = {2026},
  journal = {Nature Metabolism},
  doi = {10.1038/s42255-026-01524-w},
  url = {https://doi.org/10.1038/s42255-026-01524-w}
}

RIS

TY  - JOUR
TI  - Succinate dehydrogenase loss suppresses pyrimidine biosynthesis via succinate-mediated inhibition of aspartate transcarbamylase
AU  - Madeleine L. Hart
AU  - David Sokolov
AU  - Serwah Danquah
AU  - Eric Zheng
AU  - Alex D. Doan
AU  - Kristian Davidsen
AU  - David MacPherson
AU  - Lucas B. Sullivan
PY  - 2026
JO  - Nature Metabolism
DO  - 10.1038/s42255-026-01524-w
UR  - https://doi.org/10.1038/s42255-026-01524-w
ER  - 

APA

Hart, M. L., Sokolov, D., Danquah, S., Zheng, E., Doan, A. D., Davidsen, K., MacPherson, D., & Sullivan, L. B. (2026). Succinate dehydrogenase loss suppresses pyrimidine biosynthesis via succinate-mediated inhibition of aspartate transcarbamylase. Nature Metabolism. https://doi.org/10.1038/s42255-026-01524-w

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