Mitochondrial metabolism determines chemotherapy sensitivity in colorectal cancer

Deborah Y. Moss, Connor N. Brown, Andrew M. Shaw, Christopher McCann, Nikita Lewis, Matilda Downs, Rebecca Wurelly, Ciara Cunningham, Aaron Philips, Niamh Doherty, Sarah Gallagher, William J. McDaid, Andrew Roe, Aisling Y. Coughlan, Brenton Cavanagh, Callum Ormsby, Fiammetta Falcone, Rachel McCole, Scott Monteith, Emily Rogan, Sudhir B. Malla, Alexandra J. Emerson, Letitia Mohammed-Smith, Shaun Sharkey, Aoife Leonard, Peter F. Gallagher, Arindam Banerjee, Sandra Van Schaeybroeck, Sufyan Pandor, Brian Quinn, Brett Greer, Christopher Elliott, Sarah Maguire, Aideen E. Ryan, Philip D. Dunne, Mary Mallon, Stephanie Craig, Omar Aftab, Laura C. Greaves, Bryan P. Marzullo, Daniel A. Tennant, Vicky Coyle, Ian G. Mills, Owen Sansom, Tríona Ní Chonghaile, Daniel B. Longley, Simon S. McDade, Melissa J. LaBonte, Emma M. Kerr

Open source

DOI: 10.1038/s42255-026-01578-w
Published: 2026-07-23
Container: Nature Metabolism
Publisher: Springer Science and Business Media LLC
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s42255-026-01578-w,
  title = {Mitochondrial metabolism determines chemotherapy sensitivity in colorectal cancer},
  author = {Deborah Y. Moss and Connor N. Brown and Andrew M. Shaw and Christopher McCann and Nikita Lewis and Matilda Downs and Rebecca Wurelly and Ciara Cunningham and Aaron Philips and Niamh Doherty and Sarah Gallagher and William J. McDaid and Andrew Roe and Aisling Y. Coughlan and Brenton Cavanagh and Callum Ormsby and Fiammetta Falcone and Rachel McCole and Scott Monteith and Emily Rogan and Sudhir B. Malla and Alexandra J. Emerson and Letitia Mohammed-Smith and Shaun Sharkey and Aoife Leonard and Peter F. Gallagher and Arindam Banerjee and Sandra Van Schaeybroeck and Sufyan Pandor and Brian Quinn and Brett Greer and Christopher Elliott and Sarah Maguire and Aideen E. Ryan and Philip D. Dunne and Mary Mallon and Stephanie Craig and Omar Aftab and Laura C. Greaves and Bryan P. Marzullo and Daniel A. Tennant and Vicky Coyle and Ian G. Mills and Owen Sansom and Tríona Ní Chonghaile and Daniel B. Longley and Simon S. McDade and Melissa J. LaBonte and Emma M. Kerr},
  year = {2026},
  journal = {Nature Metabolism},
  doi = {10.1038/s42255-026-01578-w},
  url = {https://doi.org/10.1038/s42255-026-01578-w}
}

RIS

TY  - JOUR
TI  - Mitochondrial metabolism determines chemotherapy sensitivity in colorectal cancer
AU  - Deborah Y. Moss
AU  - Connor N. Brown
AU  - Andrew M. Shaw
AU  - Christopher McCann
AU  - Nikita Lewis
AU  - Matilda Downs
AU  - Rebecca Wurelly
AU  - Ciara Cunningham
AU  - Aaron Philips
AU  - Niamh Doherty
AU  - Sarah Gallagher
AU  - William J. McDaid
AU  - Andrew Roe
AU  - Aisling Y. Coughlan
AU  - Brenton Cavanagh
AU  - Callum Ormsby
AU  - Fiammetta Falcone
AU  - Rachel McCole
AU  - Scott Monteith
AU  - Emily Rogan
AU  - Sudhir B. Malla
AU  - Alexandra J. Emerson
AU  - Letitia Mohammed-Smith
AU  - Shaun Sharkey
AU  - Aoife Leonard
AU  - Peter F. Gallagher
AU  - Arindam Banerjee
AU  - Sandra Van Schaeybroeck
AU  - Sufyan Pandor
AU  - Brian Quinn
AU  - Brett Greer
AU  - Christopher Elliott
AU  - Sarah Maguire
AU  - Aideen E. Ryan
AU  - Philip D. Dunne
AU  - Mary Mallon
AU  - Stephanie Craig
AU  - Omar Aftab
AU  - Laura C. Greaves
AU  - Bryan P. Marzullo
AU  - Daniel A. Tennant
AU  - Vicky Coyle
AU  - Ian G. Mills
AU  - Owen Sansom
AU  - Tríona Ní Chonghaile
AU  - Daniel B. Longley
AU  - Simon S. McDade
AU  - Melissa J. LaBonte
AU  - Emma M. Kerr
PY  - 2026
JO  - Nature Metabolism
DO  - 10.1038/s42255-026-01578-w
UR  - https://doi.org/10.1038/s42255-026-01578-w
ER  -

APA

Moss, D. Y., Brown, C. N., Shaw, A. M., McCann, C., Lewis, N., Downs, M., Wurelly, R., Cunningham, C., Philips, A., Doherty, N., Gallagher, S., McDaid, W. J., Roe, A., Coughlan, A. Y., Cavanagh, B., Ormsby, C., Falcone, F., McCole, R., Monteith, S., Rogan, E., Malla, S. B., Emerson, A. J., Mohammed-Smith, L., Sharkey, S., Leonard, A., Gallagher, P. F., Banerjee, A., Schaeybroeck, S. V., Pandor, S., Quinn, B., Greer, B., Elliott, C., Maguire, S., Ryan, A. E., Dunne, P. D., Mallon, M., Craig, S., Aftab, O., Greaves, L. C., Marzullo, B. P., Tennant, D. A., Coyle, V., Mills, I. G., Sansom, O., Chonghaile, T. N., Longley, D. B., McDade, S. S., LaBonte, M. J., & Kerr, E. M. (2026). Mitochondrial metabolism determines chemotherapy sensitivity in colorectal cancer. Nature Metabolism. https://doi.org/10.1038/s42255-026-01578-w

Source records

crossref · retrieved 2026-09-26T21:04:22.123Z