The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.

Cole AR, Buj R, Uboveja A, Levasseur E, Tom A, Wang H, Kedziora KM, Chatoff A, Huacachino AA, Marcinkiewicz MM, Amalric A, Yang B, Tangudu NK, Noonan E, Danielson J, Naruse M, Elhaw AT, White S, Li D, Wallace CT, Keeney F, Lazure F, Elishaev E, Borho L, Townsend HA, Dowell RD, Clauset A, Jazwinska DE, Laird MS, Atiya H, Dangaj D, Coffman LG, Tseng G, Oesterreich S, Kossenkov A, Liu Q, Gomes AP, Gurkar AU, Schopfer FJ, Modugno F, Watkins SC, Zervantonakis IK, Bitler BG, Stallaert W, Hempel N, Snyder NW, Aird KM

Open source

DOI
10.1038/s43587-026-01172-5
Published
2026 Aug
Container
Nature aging
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s43587-026-01172-5,
  title = {The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.},
  author = {Cole AR and Buj R and Uboveja A and Levasseur E and Tom A and Wang H and Kedziora KM and Chatoff A and Huacachino AA and Marcinkiewicz MM and Amalric A and Yang B and Tangudu NK and Noonan E and Danielson J and Naruse M and Elhaw AT and White S and Li D and Wallace CT and Keeney F and Lazure F and Elishaev E and Borho L and Townsend HA and Dowell RD and Clauset A and Jazwinska DE and Laird MS and Atiya H and Dangaj D and Coffman LG and Tseng G and Oesterreich S and Kossenkov A and Liu Q and Gomes AP and Gurkar AU and Schopfer FJ and Modugno F and Watkins SC and Zervantonakis IK and Bitler BG and Stallaert W and Hempel N and Snyder NW and Aird KM},
  year = {2026},
  journal = {Nature aging},
  doi = {10.1038/s43587-026-01172-5},
  url = {https://doi.org/10.1038/s43587-026-01172-5}
}

RIS

TY  - JOUR
TI  - The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.
AU  - Cole AR
AU  - Buj R
AU  - Uboveja A
AU  - Levasseur E
AU  - Tom A
AU  - Wang H
AU  - Kedziora KM
AU  - Chatoff A
AU  - Huacachino AA
AU  - Marcinkiewicz MM
AU  - Amalric A
AU  - Yang B
AU  - Tangudu NK
AU  - Noonan E
AU  - Danielson J
AU  - Naruse M
AU  - Elhaw AT
AU  - White S
AU  - Li D
AU  - Wallace CT
AU  - Keeney F
AU  - Lazure F
AU  - Elishaev E
AU  - Borho L
AU  - Townsend HA
AU  - Dowell RD
AU  - Clauset A
AU  - Jazwinska DE
AU  - Laird MS
AU  - Atiya H
AU  - Dangaj D
AU  - Coffman LG
AU  - Tseng G
AU  - Oesterreich S
AU  - Kossenkov A
AU  - Liu Q
AU  - Gomes AP
AU  - Gurkar AU
AU  - Schopfer FJ
AU  - Modugno F
AU  - Watkins SC
AU  - Zervantonakis IK
AU  - Bitler BG
AU  - Stallaert W
AU  - Hempel N
AU  - Snyder NW
AU  - Aird KM
PY  - 2026
JO  - Nature aging
DO  - 10.1038/s43587-026-01172-5
UR  - https://doi.org/10.1038/s43587-026-01172-5
ER  -

APA

AR, C., R, B., A, U., E, L., A, T., H, W., KM, K., A, C., AA, H., MM, M., A, A., B, Y., NK, T., E, N., J, D., M, N., AT, E., S, W., D, L., CT, W., F, K., F, L., E, E., L, B., HA, T., RD, D., A, C., DE, J., MS, L., H, A., D, D., LG, C., G, T., S, O., A, K., Q, L., AP, G., AU, G., FJ, S., F, M., SC, W., IK, Z., BG, B., W, S., N, H., NW, S., & KM, A. (2026). The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.. Nature aging. https://doi.org/10.1038/s43587-026-01172-5

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