Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.

de Vries PS, Conomos MP, Singh K, Nicholson CJ, Jain D, Hasbani NR, Jiang W, Lee S, Lino Cardenas CL, Lutz SM, Wong D, Guo X, Yao J, Young EP, Tcheandjieu C, Hilliard AT, Bis JC, Bielak LF, Brown MR, Musharoff S, Clarke SL, Terry JG, Palmer ND, Yanek LR, Xu H, Heard-Costa N, Wessel J, Selvaraj MS, Li RH, Sun X, Turner AW, Stilp AM, Khan A, Newman AB, Rasheed A, Freedman BI, Kral BG, McHugh CP, Hodonsky C, Saleheen D, Herrington DM, Jacobs DR Jr, Nickerson DA, Boerwinkle E, Wang FF, Heiss G, Jun G, Kinney GL, Sigurslid HH, Doddapaneni H, Hall IM, Bensenor IM, Broome J, Crapo JD, Wilson JG, Smith JA, Blangero J, Vargas JD, Mosquera JV, Smith JD, Viaud-Martinez KA, Ryan KA, Young KA, Taylor KD, Lange LA, Emery LS, Bittencourt MS, Budoff MJ, Montasser ME, Yu M, Mahaney MC, Mahamdeh MS, Fornage M, Franceschini N, Lotufo PA, Natarajan P, Wong Q, Mathias RA, Gibbs RA, Do R, Mehran R, Tracy RP, Kim RW, Nelson SC, Damrauer SM, Kardia SLR, Rich SS, Fuster V, Napolioni V, Zhao W, Tian W, Yin X, Min YI, Manning AK, Peloso G, Kelly TN, O'Donnell CJ, Morrison AC, Curran JE, Zapol WM, Bowden DW, Becker LC, Correa A, Mitchell BD, Psaty BM, Carr JJ, Pereira AC, Assimes TL, Stitziel NO, Hokanson JE, Laurie CA, Rotter JI, Vasan RS, Post WS, Peyser PA, Miller CL, Malhotra R

Open source

DOI: 10.1038/s44161-023-00375-y
Published: 2023 Dec
Container: Nature cardiovascular research
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s44161-023-00375-y,
  title = {Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.},
  author = {de Vries PS and Conomos MP and Singh K and Nicholson CJ and Jain D and Hasbani NR and Jiang W and Lee S and Lino Cardenas CL and Lutz SM and Wong D and Guo X and Yao J and Young EP and Tcheandjieu C and Hilliard AT and Bis JC and Bielak LF and Brown MR and Musharoff S and Clarke SL and Terry JG and Palmer ND and Yanek LR and Xu H and Heard-Costa N and Wessel J and Selvaraj MS and Li RH and Sun X and Turner AW and Stilp AM and Khan A and Newman AB and Rasheed A and Freedman BI and Kral BG and McHugh CP and Hodonsky C and Saleheen D and Herrington DM and Jacobs DR Jr and Nickerson DA and Boerwinkle E and Wang FF and Heiss G and Jun G and Kinney GL and Sigurslid HH and Doddapaneni H and Hall IM and Bensenor IM and Broome J and Crapo JD and Wilson JG and Smith JA and Blangero J and Vargas JD and Mosquera JV and Smith JD and Viaud-Martinez KA and Ryan KA and Young KA and Taylor KD and Lange LA and Emery LS and Bittencourt MS and Budoff MJ and Montasser ME and Yu M and Mahaney MC and Mahamdeh MS and Fornage M and Franceschini N and Lotufo PA and Natarajan P and Wong Q and Mathias RA and Gibbs RA and Do R and Mehran R and Tracy RP and Kim RW and Nelson SC and Damrauer SM and Kardia SLR and Rich SS and Fuster V and Napolioni V and Zhao W and Tian W and Yin X and Min YI and Manning AK and Peloso G and Kelly TN and O'Donnell CJ and Morrison AC and Curran JE and Zapol WM and Bowden DW and Becker LC and Correa A and Mitchell BD and Psaty BM and Carr JJ and Pereira AC and Assimes TL and Stitziel NO and Hokanson JE and Laurie CA and Rotter JI and Vasan RS and Post WS and Peyser PA and Miller CL and Malhotra R},
  year = {2023},
  journal = {Nature cardiovascular research},
  doi = {10.1038/s44161-023-00375-y},
  url = {https://doi.org/10.1038/s44161-023-00375-y}
}

RIS

TY  - JOUR
TI  - Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.
AU  - de Vries PS
AU  - Conomos MP
AU  - Singh K
AU  - Nicholson CJ
AU  - Jain D
AU  - Hasbani NR
AU  - Jiang W
AU  - Lee S
AU  - Lino Cardenas CL
AU  - Lutz SM
AU  - Wong D
AU  - Guo X
AU  - Yao J
AU  - Young EP
AU  - Tcheandjieu C
AU  - Hilliard AT
AU  - Bis JC
AU  - Bielak LF
AU  - Brown MR
AU  - Musharoff S
AU  - Clarke SL
AU  - Terry JG
AU  - Palmer ND
AU  - Yanek LR
AU  - Xu H
AU  - Heard-Costa N
AU  - Wessel J
AU  - Selvaraj MS
AU  - Li RH
AU  - Sun X
AU  - Turner AW
AU  - Stilp AM
AU  - Khan A
AU  - Newman AB
AU  - Rasheed A
AU  - Freedman BI
AU  - Kral BG
AU  - McHugh CP
AU  - Hodonsky C
AU  - Saleheen D
AU  - Herrington DM
AU  - Jacobs DR Jr
AU  - Nickerson DA
AU  - Boerwinkle E
AU  - Wang FF
AU  - Heiss G
AU  - Jun G
AU  - Kinney GL
AU  - Sigurslid HH
AU  - Doddapaneni H
AU  - Hall IM
AU  - Bensenor IM
AU  - Broome J
AU  - Crapo JD
AU  - Wilson JG
AU  - Smith JA
AU  - Blangero J
AU  - Vargas JD
AU  - Mosquera JV
AU  - Smith JD
AU  - Viaud-Martinez KA
AU  - Ryan KA
AU  - Young KA
AU  - Taylor KD
AU  - Lange LA
AU  - Emery LS
AU  - Bittencourt MS
AU  - Budoff MJ
AU  - Montasser ME
AU  - Yu M
AU  - Mahaney MC
AU  - Mahamdeh MS
AU  - Fornage M
AU  - Franceschini N
AU  - Lotufo PA
AU  - Natarajan P
AU  - Wong Q
AU  - Mathias RA
AU  - Gibbs RA
AU  - Do R
AU  - Mehran R
AU  - Tracy RP
AU  - Kim RW
AU  - Nelson SC
AU  - Damrauer SM
AU  - Kardia SLR
AU  - Rich SS
AU  - Fuster V
AU  - Napolioni V
AU  - Zhao W
AU  - Tian W
AU  - Yin X
AU  - Min YI
AU  - Manning AK
AU  - Peloso G
AU  - Kelly TN
AU  - O'Donnell CJ
AU  - Morrison AC
AU  - Curran JE
AU  - Zapol WM
AU  - Bowden DW
AU  - Becker LC
AU  - Correa A
AU  - Mitchell BD
AU  - Psaty BM
AU  - Carr JJ
AU  - Pereira AC
AU  - Assimes TL
AU  - Stitziel NO
AU  - Hokanson JE
AU  - Laurie CA
AU  - Rotter JI
AU  - Vasan RS
AU  - Post WS
AU  - Peyser PA
AU  - Miller CL
AU  - Malhotra R
PY  - 2023
JO  - Nature cardiovascular research
DO  - 10.1038/s44161-023-00375-y
UR  - https://doi.org/10.1038/s44161-023-00375-y
ER  -

APA

PS, D. V., MP, C., K, S., CJ, N., D, J., NR, H., W, J., S, L., CL, L. C., SM, L., D, W., X, G., J, Y., EP, Y., C, T., AT, H., JC, B., LF, B., MR, B., S, M., SL, C., JG, T., ND, P., LR, Y., H, X., N, H., J, W., MS, S., RH, L., X, S., AW, T., AM, S., A, K., AB, N., A, R., BI, F., BG, K., CP, M., C, H., D, S., DM, H., Jr, J. D., DA, N., E, B., FF, W., G, H., G, J., GL, K., HH, S., H, D., IM, H., IM, B., J, B., JD, C., JG, W., JA, S., J, B., JD, V., JV, M., JD, S., KA, V., KA, R., KA, Y., KD, T., LA, L., LS, E., MS, B., MJ, B., ME, M., M, Y., MC, M., MS, M., M, F., N, F., PA, L., P, N., Q, W., RA, M., RA, G., R, D., R, M., RP, T., RW, K., SC, N., SM, D., SLR, K., SS, R., V, F., V, N., W, Z., W, T., X, Y., YI, M., AK, M., G, P., TN, K., CJ, O., AC, M., JE, C., WM, Z., DW, B., LC, B., A, C., BD, M., BM, P., JJ, C., AC, P., TL, A., NO, S., JE, H., CA, L., JI, R., RS, V., WS, P., PA, P., CL, M., & R, M. (2023). Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.. Nature cardiovascular research. https://doi.org/10.1038/s44161-023-00375-y

Source records

pubmed · retrieved 2026-09-26T14:59:11.023Z